Fam3b (FAM3 metabolism regulating signaling molecule B) - Rat Genome Database

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Gene: Fam3b (FAM3 metabolism regulating signaling molecule B) Ictidomys tridecemlineatus
Analyze
Symbol: Fam3b
Name: FAM3 metabolism regulating signaling molecule B
RGD ID: 12565353
Description: ENCODES a protein that exhibits carbohydrate binding (inferred); INVOLVED IN insulin secretion (inferred); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: family with sequence similarity 3 member B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497135,149,735 - 35,178,093 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365002,289,687 - 2,318,977 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365002,289,795 - 2,317,616 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Fam3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497135,149,735 - 35,178,093 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365002,289,687 - 2,318,977 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365002,289,795 - 2,317,616 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382141,304,242 - 41,357,727 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2141,304,212 - 41,357,727 (+)EnsemblGRCh38hg38GRCh38
GRCh372142,688,728 - 42,729,654 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362141,610,531 - 41,651,524 (+)NCBINCBI36Build 36hg18NCBI36
Celera2127,886,894 - 27,927,901 (+)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2128,157,559 - 28,198,557 (+)NCBIHuRef
CHM1_12142,249,456 - 42,290,457 (+)NCBICHM1_1
T2T-CHM13v2.02139,692,606 - 39,746,338 (+)NCBIT2T-CHM13v2.0
Fam3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391697,272,165 - 97,306,136 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1697,272,165 - 97,316,016 (-)EnsemblGRCm39 Ensembl
GRCm381697,470,965 - 97,504,936 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1697,470,965 - 97,514,816 (-)EnsemblGRCm38mm10GRCm38
MGSCv371697,692,693 - 97,726,543 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361697,575,996 - 97,659,852 (-)NCBIMGSCv36mm8
Celera1698,531,405 - 98,565,114 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1657.47NCBI
Fam3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,300,926 - 50,333,296 (-)NCBIGRCr8
mRatBN7.21136,831,532 - 36,863,902 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1136,831,532 - 36,869,713 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1145,480,008 - 45,512,453 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01138,151,386 - 38,183,828 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01137,311,313 - 37,343,761 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01137,922,308 - 37,993,279 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1137,922,292 - 37,993,207 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,429,763 - 41,503,454 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,470,404 - 37,505,705 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11137,528,141 - 37,558,745 (-)NCBI
Celera1136,718,301 - 36,749,239 (-)NCBICelera
Cytogenetic Map11q12NCBI
Fam3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540740,914,239 - 40,932,177 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540740,914,408 - 40,939,850 (-)NCBIChiLan1.0ChiLan1.0
FAM3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22237,396,847 - 37,438,869 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12132,251,107 - 32,293,169 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02127,650,185 - 27,692,249 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12140,979,149 - 41,020,089 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2140,979,149 - 41,020,089 (+)Ensemblpanpan1.1panPan2
FAM3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13135,805,981 - 35,844,258 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3135,806,217 - 35,844,263 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3134,961,227 - 34,999,135 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03135,323,709 - 35,361,728 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3135,323,758 - 35,361,733 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13135,219,538 - 35,257,553 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03135,197,593 - 35,235,594 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03135,691,726 - 35,729,740 (+)NCBIUU_Cfam_GSD_1.0
FAM3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13204,752,196 - 204,796,777 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113204,746,338 - 204,796,792 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213215,061,989 - 215,072,431 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FAM3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1285,211,126 - 85,277,034 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl285,223,553 - 85,277,839 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605413,075,832 - 13,129,760 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fam3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474528,639,087 - 28,659,627 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474528,638,914 - 28,658,930 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005323470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000006378   ⟹   ENSSTOP00000005702
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365002,289,687 - 2,318,977 (+)Ensembl
RefSeq Acc Id: XM_005323470   ⟹   XP_005323527
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440497135,149,735 - 35,178,093 (-)NCBI
SpeTri2.0NW_0049365002,289,795 - 2,317,616 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005323527 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000005702.3
GenBank Protein KAG3284013 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005323527   ⟸   XM_005323470
- UniProtKB: I3M7T4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000005702   ⟸   ENSSTOT00000006378
Protein Domains
ILEI/PANDER


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000006382 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000006378.3 UniProtKB/TrEMBL
InterPro FAM3 UniProtKB/TrEMBL
  ILEI/PANDER_dom UniProtKB/TrEMBL
NCBI Gene Fam3b ENTREZGENE
PANTHER PTHR14592 UniProtKB/TrEMBL
  PTHR14592:SF2 UniProtKB/TrEMBL
Pfam ILEI UniProtKB/TrEMBL
UniProt I3M7T4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-24 Fam3b  FAM3 metabolism regulating signaling molecule B  Fam3b  family with sequence similarity 3 member B  Symbol and/or name change 5135510 APPROVED