Fbxl19 (F-box and leucine rich repeat protein 19) - Rat Genome Database

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Gene: Fbxl19 (F-box and leucine rich repeat protein 19) Ictidomys tridecemlineatus
Analyze
Symbol: Fbxl19
Name: F-box and leucine rich repeat protein 19
RGD ID: 12558906
Description: ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (ortholog); unmethylated CpG binding (ortholog); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); ASSOCIATED WITH branched-chain keto acid dehydrogenase kinase deficiency (ortholog); generalized epilepsy with febrile seizures plus 9 (ortholog); genetic disease (ortholog); FOUND IN SCF ubiquitin ligase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: F-box/LRR-repeat protein 19
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344125,212,854 - 125,234,738 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650113,312,304 - 13,332,644 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650113,312,311 - 13,332,599 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Fbxl19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344125,212,854 - 125,234,738 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650113,312,304 - 13,332,644 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650113,312,311 - 13,332,599 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXL19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,922,851 - 30,948,783 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,923,055 - 30,948,783 (+)EnsemblGRCh38hg38GRCh38
GRCh371630,934,172 - 30,960,104 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,843,397 - 30,867,605 (+)NCBINCBI36Build 36hg18NCBI36
Build 341630,844,713 - 30,867,605NCBI
Celera1629,337,602 - 29,361,786 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1628,497,051 - 28,522,774 (+)NCBIHuRef
CHM1_11632,251,400 - 32,277,114 (+)NCBICHM1_1
T2T-CHM13v2.01631,310,313 - 31,336,246 (+)NCBIT2T-CHM13v2.0
Fbxl19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397127,343,059 - 127,368,655 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7127,343,715 - 127,368,655 (+)EnsemblGRCm39 Ensembl
GRCm387127,743,887 - 127,769,483 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,744,543 - 127,769,483 (+)EnsemblGRCm38mm10GRCm38
MGSCv377134,890,289 - 134,912,442 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367127,537,923 - 127,560,076 (+)NCBIMGSCv36mm8
Celera7127,583,121 - 127,604,416 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.71NCBI
Fbxl19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,786,981 - 191,811,314 (+)NCBIGRCr8
mRatBN7.21182,356,899 - 182,380,839 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,360,830 - 182,380,083 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,711,371 - 190,730,624 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01197,897,465 - 197,916,719 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01190,567,926 - 190,587,189 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01199,196,126 - 199,217,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,196,059 - 199,216,391 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,218,078 - 206,238,886 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,034,148 - 187,053,401 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11187,182,647 - 187,203,486 (+)NCBI
Celera1180,011,949 - 180,031,204 (+)NCBICelera
Cytogenetic Map1q37NCBI
Fbxl19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554937,768,802 - 7,798,546 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554937,768,802 - 7,798,546 (+)NCBIChiLan1.0ChiLan1.0
FBXL19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21834,129,364 - 34,159,283 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11638,927,660 - 38,960,696 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01624,020,365 - 24,046,217 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11631,290,476 - 31,315,169 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1631,290,476 - 31,315,169 (+)Ensemblpanpan1.1panPan2
FBXL19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,254,595 - 17,274,103 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,248,884 - 17,274,850 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha618,830,218 - 18,851,149 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,385,488 - 17,406,421 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,384,743 - 17,403,568 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,185,843 - 17,206,774 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,104,981 - 17,125,912 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,417,538 - 17,438,469 (-)NCBIUU_Cfam_GSD_1.0
FBXL19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl317,497,488 - 17,521,445 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1317,497,486 - 17,521,759 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2317,782,771 - 17,807,043 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FBXL19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1527,612,889 - 27,638,403 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl527,614,479 - 27,638,636 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660681,832,968 - 1,858,985 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxl19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478214,000,230 - 14,026,749 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000005343   ⟹   ENSSTOP00000004788
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493650113,312,304 - 13,332,644 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000031369   ⟹   ENSSTOP00000026709
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493650113,313,154 - 13,332,644 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000034617   ⟹   ENSSTOP00000030256
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493650113,313,674 - 13,331,018 (+)Ensembl
RefSeq Acc Id: XM_013357982   ⟹   XP_013213436
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344125,214,450 - 125,234,738 (+)NCBI
SpeTri2.0NW_00493650113,312,311 - 13,332,599 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040278753   ⟹   XP_040134687
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344125,214,536 - 125,234,738 (+)NCBI
RefSeq Acc Id: XM_040278754   ⟹   XP_040134688
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344125,214,535 - 125,234,738 (+)NCBI
RefSeq Acc Id: XM_040278755   ⟹   XP_040134689
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344125,212,884 - 125,234,738 (+)NCBI
RefSeq Acc Id: XM_040278757   ⟹   XP_040134691
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024409344125,212,854 - 125,234,738 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013213436   ⟸   XM_013357982
- Peptide Label: isoform X4
- UniProtKB: I3M5X3 (UniProtKB/TrEMBL),   A0A287D9S8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040134691   ⟸   XM_040278757
- Peptide Label: isoform X5
- UniProtKB: A0A287D9S8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134689   ⟸   XM_040278755
- Peptide Label: isoform X3
- UniProtKB: A0A287D9S8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134688   ⟸   XM_040278754
- Peptide Label: isoform X2
- UniProtKB: A0A287D9S8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040134687   ⟸   XM_040278753
- Peptide Label: isoform X1
- UniProtKB: A0A287D9S8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000026709   ⟸   ENSSTOT00000031369
RefSeq Acc Id: ENSSTOP00000030256   ⟸   ENSSTOT00000034617
RefSeq Acc Id: ENSSTOP00000004788   ⟸   ENSSTOT00000005343
Protein Domains
CXXC-type   PHD-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000005331 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000005343.3 UniProtKB/TrEMBL
  ENSSTOT00000031369.1 UniProtKB/TrEMBL
  ENSSTOT00000034617.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro F-box_dom UniProtKB/TrEMBL
  Leu-rich_rpt_Cys-con_subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_CXXC UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Fbxl19 ENTREZGENE
PANTHER F-BOX/LRR-REPEAT PROTEIN 19 UniProtKB/TrEMBL
  PHD/F-BOX CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam F-box-like UniProtKB/TrEMBL
  PHD_4 UniProtKB/TrEMBL
  zf-CXXC UniProtKB/TrEMBL
PROSITE ZF_CXXC UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
SMART FBOX UniProtKB/TrEMBL
  LRR_CC UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A287D9S8 ENTREZGENE, UniProtKB/TrEMBL
  I3M5X3 ENTREZGENE, UniProtKB/TrEMBL