Arfgap1 (ADP ribosylation factor GTPase activating protein 1) - Rat Genome Database

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Pathways
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Gene: Arfgap1 (ADP ribosylation factor GTPase activating protein 1) Ictidomys tridecemlineatus
Analyze
Symbol: Arfgap1
Name: ADP ribosylation factor GTPase activating protein 1
RGD ID: 12558290
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of endocytosis (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; ASSOCIATED WITH autosomal dominant nocturnal frontal lobe epilepsy (ortholog); benign familial infantile seizures 6 (ortholog); developmental and epileptic encephalopathy (ortholog); FOUND IN Golgi membrane (ortholog); postsynaptic density (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ADP ribosylation factor GTPase activating protein 1, transcript variant X1; ADP ribosylation factor GTPase activating protein 1, transcript variant X2; ADP ribosylation factor GTPase activating protein 1, transcript variant X3; ADP ribosylation factor GTPase activating protein 1, transcript variant X4; ADP ribosylation factor GTPase activating protein 1, transcript variant X5; ADP-ribosylation factor GTPase-activating protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,174,022 - 195,187,226 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651410,627,639 - 10,640,869 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651410,627,700 - 10,641,157 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Golgi membrane  (IEA,ISO)
postsynaptic density  (ISO)
synapse  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Arfgap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,174,022 - 195,187,226 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651410,627,639 - 10,640,869 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651410,627,700 - 10,641,157 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARFGAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382063,272,813 - 63,289,790 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2063,272,785 - 63,289,790 (+)EnsemblGRCh38hg38GRCh38
GRCh372061,904,165 - 61,921,142 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362061,374,610 - 61,391,587 (+)NCBINCBI36Build 36hg18NCBI36
Build 342061,374,609 - 61,391,587NCBI
Celera2058,581,641 - 58,598,618 (+)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2058,629,588 - 58,646,600 (+)NCBIHuRef
CHM1_12061,805,186 - 61,822,225 (+)NCBICHM1_1
T2T-CHM13v2.02065,078,685 - 65,095,673 (+)NCBIT2T-CHM13v2.0
Arfgap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392180,608,290 - 180,624,319 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2180,609,018 - 180,624,319 (+)EnsemblGRCm39 Ensembl
GRCm382180,967,225 - 180,982,526 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2180,967,225 - 180,982,526 (+)EnsemblGRCm38mm10GRCm38
MGSCv372180,701,930 - 180,717,229 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362180,896,677 - 180,911,850 (+)NCBIMGSCv36mm8
Celera2185,053,714 - 185,069,012 (+)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2103.53NCBI
Arfgap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83188,462,125 - 188,477,515 (+)NCBIGRCr8
mRatBN7.23168,084,560 - 168,099,948 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,084,614 - 168,099,933 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3172,464,963 - 172,479,000 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03181,424,054 - 181,438,091 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,085,603 - 178,099,635 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03176,475,847 - 176,490,642 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3176,475,893 - 176,489,925 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03180,185,674 - 180,201,025 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,075,313 - 170,100,744 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13169,981,348 - 170,006,780 (+)NCBI
Celera3164,486,283 - 164,500,316 (-)NCBICelera
Cytogenetic Map3q43NCBI
Arfgap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955528877,073 - 893,484 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955528878,837 - 893,427 (-)NCBIChiLan1.0ChiLan1.0
ARFGAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22169,061,683 - 69,082,400 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12069,053,689 - 69,071,614 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02059,656,731 - 59,674,802 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12061,197,583 - 61,214,635 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2061,197,583 - 61,214,635 (+)Ensemblpanpan1.1panPan2
ARFGAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12446,983,944 - 46,995,552 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2446,983,939 - 46,995,548 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2446,167,782 - 46,179,384 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02447,937,705 - 47,949,300 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2447,937,684 - 47,949,305 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12446,952,991 - 46,964,587 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02447,077,281 - 47,088,873 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,833,394 - 47,844,998 (+)NCBIUU_Cfam_GSD_1.0
ARFGAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,380,091 - 62,391,856 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11762,380,060 - 62,391,836 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ARFGAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12918,508 - 936,175 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2917,479 - 936,138 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605048,561,151 - 48,579,371 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arfgap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474128,971,239 - 28,986,717 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474128,971,320 - 28,986,699 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000025868   ⟹   ENSSTOP00000021356
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493651410,627,716 - 10,640,869 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000033561   ⟹   ENSSTOP00000024650
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493651410,627,639 - 10,640,759 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000036548   ⟹   ENSSTOP00000026471
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493651410,627,639 - 10,640,869 (+)Ensembl
RefSeq Acc Id: XM_005325320   ⟹   XP_005325377
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640195,178,094 - 195,187,226 (+)NCBI
SpeTri2.0NW_00493651410,631,737 - 10,641,157 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013358658   ⟹   XP_013214112
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640195,174,022 - 195,187,226 (+)NCBI
SpeTri2.0NW_00493651410,627,700 - 10,640,870 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013358659   ⟹   XP_013214113
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640195,174,022 - 195,187,226 (+)NCBI
SpeTri2.0NW_00493651410,627,700 - 10,640,870 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021726386   ⟹   XP_021582061
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640195,174,022 - 195,187,226 (+)NCBI
SpeTri2.0NW_00493651410,627,700 - 10,640,870 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021726387   ⟹   XP_021582062
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640195,174,022 - 195,187,226 (+)NCBI
SpeTri2.0NW_00493651410,627,700 - 10,640,870 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040275718   ⟹   XP_040131652
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640195,174,022 - 195,187,226 (+)NCBI
RefSeq Acc Id: XM_040275719   ⟹   XP_040131653
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640195,174,022 - 195,187,226 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013214112   ⟸   XM_013358658
- Peptide Label: isoform X1
- UniProtKB: A0A287CYX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013214113   ⟸   XM_013358659
- Peptide Label: isoform X2
- UniProtKB: I3NAF9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005325377   ⟸   XM_005325320
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_021582061   ⟸   XM_021726386
- Peptide Label: isoform X4
- UniProtKB: A0A287CTJ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021582062   ⟸   XM_021726387
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_040131652   ⟸   XM_040275718
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040131653   ⟸   XM_040275719
- Peptide Label: isoform X5
RefSeq Acc Id: ENSSTOP00000024650   ⟸   ENSSTOT00000033561
RefSeq Acc Id: ENSSTOP00000021356   ⟸   ENSSTOT00000025868
RefSeq Acc Id: ENSSTOP00000026471   ⟸   ENSSTOT00000036548
Protein Domains
Arf-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000022151 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000025868.2 UniProtKB/TrEMBL
  ENSSTOT00000033561.1 UniProtKB/TrEMBL
  ENSSTOT00000036548.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.150 UniProtKB/TrEMBL
InterPro ARFGAP/RecO UniProtKB/TrEMBL
  ArfGAP_dom UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/TrEMBL
NCBI Gene Arfgap1 ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 UniProtKB/TrEMBL
  ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 UniProtKB/TrEMBL
Pfam ArfGap UniProtKB/TrEMBL
PRINTS REVINTRACTNG UniProtKB/TrEMBL
PROSITE ARFGAP UniProtKB/TrEMBL
SMART ArfGap UniProtKB/TrEMBL
Superfamily-SCOP SSF57863 UniProtKB/TrEMBL
UniProt A0A287CTJ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A287CYX5 ENTREZGENE, UniProtKB/TrEMBL
  I3NAF9 ENTREZGENE, UniProtKB/TrEMBL