Ikzf2 (IKAROS family zinc finger 2) - Rat Genome Database

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Gene: Ikzf2 (IKAROS family zinc finger 2) Ictidomys tridecemlineatus
Analyze
Symbol: Ikzf2
Name: IKAROS family zinc finger 2
RGD ID: 12554874
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH acute lymphoblastic leukemia (ortholog); adult T-cell leukemia/lymphoma (ortholog); COVID-19 (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: IKAROS family zinc finger 2, transcript variant X1; IKAROS family zinc finger 2, transcript variant X2; IKAROS family zinc finger 2, transcript variant X3; IKAROS family zinc finger 2, transcript variant X4; zinc finger protein Helios
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303168,945,604 - 169,100,732 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365863,525,933 - 3,674,061 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365863,522,614 - 3,676,070 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (ISO)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ikzf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303168,945,604 - 169,100,732 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365863,525,933 - 3,674,061 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365863,522,614 - 3,676,070 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IKZF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382212,999,698 - 213,152,456 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2212,999,691 - 213,152,427 (-)EnsemblGRCh38hg38GRCh38
GRCh372213,864,422 - 214,017,180 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362213,572,653 - 213,724,578 (-)NCBINCBI36Build 36hg18NCBI36
Build 342213,696,849 - 213,840,564NCBI
Celera2207,628,331 - 207,780,208 (-)NCBICelera
Cytogenetic Map2q34NCBI
HuRef2205,713,880 - 205,865,875 (-)NCBIHuRef
CHM1_12213,870,566 - 214,022,519 (-)NCBICHM1_1
T2T-CHM13v2.02213,416,757 - 213,633,302 (-)NCBIT2T-CHM13v2.0
Ikzf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39169,570,382 - 69,726,510 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl169,570,373 - 69,726,404 (-)EnsemblGRCm39 Ensembl
GRCm38169,531,207 - 69,687,351 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl169,531,214 - 69,687,245 (-)EnsemblGRCm38mm10GRCm38
MGSCv37169,577,781 - 69,732,534 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36169,470,598 - 69,619,029 (-)NCBIMGSCv36mm8
Celera170,088,227 - 70,243,344 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map134.9NCBI
Ikzf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8978,495,670 - 78,640,896 (-)NCBIGRCr8
mRatBN7.2971,046,038 - 71,191,296 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl971,042,440 - 71,190,867 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx979,540,029 - 79,684,499 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0984,668,896 - 84,813,364 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0983,057,327 - 83,201,968 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0976,621,230 - 76,771,017 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl976,621,230 - 76,768,806 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0976,401,302 - 76,550,479 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4968,436,877 - 68,585,545 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1968,594,207 - 68,732,574 (-)NCBI
Celera968,498,043 - 68,644,480 (-)NCBICelera
Cytogenetic Map9q33NCBI
Ikzf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554572,608,894 - 2,755,455 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554572,608,892 - 2,763,036 (+)NCBIChiLan1.0ChiLan1.0
IKZF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213115,622,820 - 115,773,953 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B115,639,394 - 115,790,868 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B100,255,430 - 100,407,395 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B218,731,828 - 218,882,087 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B218,737,506 - 218,882,087 (-)Ensemblpanpan1.1panPan2
IKZF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13720,508,647 - 20,662,549 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3720,516,239 - 20,661,298 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3721,387,600 - 21,542,297 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03720,500,779 - 20,655,655 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3720,504,445 - 20,653,695 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13720,407,319 - 20,561,909 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03720,355,896 - 20,510,382 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03720,373,416 - 20,528,153 (-)NCBIUU_Cfam_GSD_1.0
IKZF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15115,512,179 - 115,677,374 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115115,512,160 - 115,677,503 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215127,875,632 - 127,901,288 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IKZF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11098,750,782 - 98,909,061 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1098,759,037 - 98,909,007 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040100,492,927 - 100,649,376 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ikzf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247653,017,571 - 3,164,136 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247653,016,569 - 3,171,443 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000011684   ⟹   ENSSTOP00000010485
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365863,525,933 - 3,672,666 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000033699   ⟹   ENSSTOP00000028505
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365863,529,019 - 3,672,666 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000037142   ⟹   ENSSTOP00000025068
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365863,525,933 - 3,674,061 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000038277   ⟹   ENSSTOP00000023991
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365863,529,019 - 3,672,666 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000038954   ⟹   ENSSTOP00000032274
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365863,529,019 - 3,672,666 (+)Ensembl
RefSeq Acc Id: XM_005331859   ⟹   XP_005331916
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303168,945,604 - 169,099,948 (-)NCBI
SpeTri2.0NW_0049365863,525,943 - 3,676,070 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005331860   ⟹   XP_005331917
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303168,945,604 - 169,099,948 (-)NCBI
SpeTri2.0NW_0049365863,525,943 - 3,672,849 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021730737   ⟹   XP_021586412
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303168,945,604 - 169,099,948 (-)NCBI
SpeTri2.0NW_0049365863,525,943 - 3,676,070 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021730738   ⟹   XP_021586413
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303168,945,604 - 169,100,732 (-)NCBI
SpeTri2.0NW_0049365863,522,614 - 3,676,070 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040294872   ⟹   XP_040150806
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303168,945,604 - 169,099,948 (-)NCBI
RefSeq Acc Id: XM_040294873   ⟹   XP_040150807
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303168,945,604 - 169,099,617 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005331917   ⟸   XM_005331860
- Peptide Label: isoform X4
- UniProtKB: A0A287CRT4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005331916   ⟸   XM_005331859
- Peptide Label: isoform X2
- UniProtKB: I3MHT9 (UniProtKB/TrEMBL),   A0A287D4R6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021586413   ⟸   XM_021730738
- Peptide Label: isoform X2
- UniProtKB: I3MHT9 (UniProtKB/TrEMBL),   A0A287D4R6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021586412   ⟸   XM_021730737
- Peptide Label: isoform X2
- UniProtKB: I3MHT9 (UniProtKB/TrEMBL),   A0A287D4R6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040150806   ⟸   XM_040294872
- Peptide Label: isoform X1
- UniProtKB: A0A287D4R6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040150807   ⟸   XM_040294873
- Peptide Label: isoform X3
- UniProtKB: A0A287CRT4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000010485   ⟸   ENSSTOT00000011684
RefSeq Acc Id: ENSSTOP00000025068   ⟸   ENSSTOT00000037142
RefSeq Acc Id: ENSSTOP00000023991   ⟸   ENSSTOT00000038277
RefSeq Acc Id: ENSSTOP00000028505   ⟸   ENSSTOT00000033699
RefSeq Acc Id: ENSSTOP00000032274   ⟸   ENSSTOT00000038954
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011683 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011684.3 UniProtKB/TrEMBL
  ENSSTOT00000033699.1 UniProtKB/TrEMBL
  ENSSTOT00000037142.1 UniProtKB/TrEMBL
  ENSSTOT00000038277.1 UniProtKB/TrEMBL
  ENSSTOT00000038954.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene Ikzf2 ENTREZGENE
PANTHER ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN HELIOS UniProtKB/TrEMBL
  ZINC FINGER PROTEIN PEGASUS UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A287CRT4 ENTREZGENE, UniProtKB/TrEMBL
  A0A287D4R6 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DFF2_ICTTR UniProtKB/TrEMBL
  I3MHT9 ENTREZGENE, UniProtKB/TrEMBL