Mmp8 (matrix metallopeptidase 8) - Rat Genome Database

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Gene: Mmp8 (matrix metallopeptidase 8) Ictidomys tridecemlineatus
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Symbol: Mmp8
Name: matrix metallopeptidase 8
RGD ID: 12552500
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); endopeptidase activity (ortholog); metallopeptidase activity (ortholog); INVOLVED IN endodermal cell differentiation (ortholog); negative regulation of gene expression (ortholog); negative regulation of interleukin-10 production (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); breast cancer (ortholog); carotid artery disease (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: matrix metallopeptidase 8 (neutrophil collagenase); neutrophil collagenase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494786,297,496 - 86,305,565 (-)NCBI
SpeTri2.0NW_0049365515,228,950 - 5,238,948 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
Mmp8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494786,297,496 - 86,305,565 (-)NCBI
SpeTri2.0NW_0049365515,228,950 - 5,238,948 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11102,711,796 - 102,727,050 (-)EnsemblGRCh38hg38GRCh38
GRCh3811102,711,796 - 102,724,967 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711102,582,527 - 102,595,685 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611102,088,540 - 102,100,868 (-)NCBINCBI36hg18NCBI36
Build 3411102,088,539 - 102,100,868NCBI
Celera1199,743,725 - 99,756,878 (-)NCBI
Cytogenetic Map11q22.2NCBI
HuRef1198,509,472 - 98,522,626 (-)NCBIHuRef
CHM1_111102,465,498 - 102,478,648 (-)NCBICHM1_1
Mmp8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3997,558,430 - 7,568,487 (+)NCBIGRCm39mm39
GRCm39 Ensembl97,558,457 - 7,568,486 (+)Ensembl
GRCm3897,558,429 - 7,568,486 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl97,558,456 - 7,568,485 (+)EnsemblGRCm38mm10GRCm38
MGSCv3797,558,429 - 7,568,486 (+)NCBIGRCm37mm9NCBIm37
MGSCv3697,558,460 - 7,568,485 (+)NCBImm8
Celera94,948,941 - 4,958,998 (+)NCBICelera
Cytogenetic Map9A1NCBI
Mmp8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.284,724,009 - 4,732,956 (+)NCBI
Rnor_6.0 Ensembl85,768,811 - 5,778,702 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.085,768,808 - 5,777,741 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.085,771,659 - 5,780,576 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.484,402,124 - 4,410,976 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.184,402,123 - 4,410,976 (+)NCBI
Celera86,283,716 - 6,292,568 (+)NCBICelera
Cytogenetic Map8q11NCBI
Mmp8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554125,928,997 - 5,939,012 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554125,928,997 - 5,939,012 (-)NCBIChiLan1.0ChiLan1.0
MMP8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111101,143,372 - 101,156,695 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11101,143,268 - 101,156,736 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01197,650,408 - 97,663,731 (-)NCBIMhudiblu_PPA_v0panPan3
MMP8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1529,036,381 - 29,047,180 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl529,035,820 - 29,046,808 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha528,984,875 - 28,995,648 (+)NCBI
ROS_Cfam_1.0529,087,831 - 29,098,581 (+)NCBI
UMICH_Zoey_3.1529,122,825 - 29,133,583 (+)NCBI
UNSW_CanFamBas_1.0529,002,064 - 29,012,820 (+)NCBI
UU_Cfam_GSD_1.0529,177,264 - 29,188,014 (+)NCBI
MMP8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl933,384,028 - 33,396,947 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1933,384,034 - 33,397,637 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2937,330,738 - 37,343,699 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MMP8
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,097,620 - 94,110,114 (-)NCBI
ChlSab1.1 Ensembl194,097,896 - 94,109,432 (-)Ensembl
Vero_WHO_p1.0NW_02366604331,764,839 - 31,777,953 (+)NCBI
Mmp8
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624878124,396 - 174,584 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005329120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005329120   ⟹   XP_005329177
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494786,297,496 - 86,305,565 (-)NCBI
SpeTri2.0NW_0049365515,228,950 - 5,238,948 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005329177 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005329177   ⟸   XM_005329120
- Sequence:
Protein Domains
ZnMc


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008539 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000007654 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008539 UniProtKB/TrEMBL
Gene3D-CATH 2.110.10.10 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro Hemopexin-like_dom UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/TrEMBL
  Hemopexin_CS UniProtKB/TrEMBL
  M10A_MMP UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  MMP8 UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/TrEMBL
  Pept_M10A UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/TrEMBL
NCBI Gene Mmp8 ENTREZGENE
PANTHER PTHR10201:SF137 UniProtKB/TrEMBL
Pfam Hemopexin UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/TrEMBL
PIRSF Peptidase_M10A_matrix UniProtKB/TrEMBL
PRINTS MATRIXIN UniProtKB/TrEMBL
PROSITE HEMOPEXIN UniProtKB/TrEMBL
  HEMOPEXIN_2 UniProtKB/TrEMBL
SMART SM00120 UniProtKB/TrEMBL
  ZnMc UniProtKB/TrEMBL
Superfamily-SCOP SSF50923 UniProtKB/TrEMBL
UniProt I3MBT4_ICTTR UniProtKB/TrEMBL