Spr (sepiapterin reductase) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Spr (sepiapterin reductase) Ictidomys tridecemlineatus
Analyze
Symbol: Spr
Name: sepiapterin reductase
RGD ID: 12552012
Description: ENCODES a protein that exhibits protein homodimerization activity (ortholog); sepiapterin reductase activity (ortholog); INVOLVED IN cell morphogenesis involved in neuron differentiation (ortholog); dopamine metabolic process (ortholog); L-phenylalanine metabolic process (ortholog); PARTICIPATES IN dopa responsive dystonia pathway; Segawa syndrome pathway; ASSOCIATED WITH Alstrom syndrome (ortholog); COVID-19 (ortholog); dystonia (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629211,872,315 - 11,877,409 (-)NCBI
SpeTri2.0NW_00493649116,693,940 - 16,699,040 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Spr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629211,872,315 - 11,877,409 (-)NCBI
SpeTri2.0NW_00493649116,693,940 - 16,699,040 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl272,887,382 - 72,892,158 (+)EnsemblGRCh38hg38GRCh38
GRCh38272,887,408 - 72,892,158 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37273,114,537 - 73,119,287 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36272,968,056 - 72,972,794 (+)NCBINCBI36hg18NCBI36
Build 34273,026,202 - 73,030,941NCBI
Celera272,965,357 - 72,970,134 (+)NCBI
Cytogenetic Map2p13.2NCBI
HuRef272,850,110 - 72,854,887 (+)NCBIHuRef
CHM1_1273,044,688 - 73,049,465 (+)NCBICHM1_1
Spr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39685,110,662 - 85,114,746 (-)NCBIGRCm39mm39
GRCm39 Ensembl685,107,158 - 85,114,748 (-)Ensembl
GRCm38685,133,680 - 85,137,764 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl685,130,176 - 85,137,766 (-)EnsemblGRCm38mm10GRCm38
MGSCv37685,083,674 - 85,087,758 (-)NCBIGRCm37mm9NCBIm37
MGSCv36685,099,343 - 85,103,476 (-)NCBImm8
Celera687,104,831 - 87,108,907 (-)NCBICelera
Cytogenetic Map6C3NCBI
cM Map637.15NCBI
Spr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24117,671,948 - 117,676,292 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl4117,671,949 - 117,675,678 (-)Ensembl
Rnor_6.04116,912,343 - 116,916,073 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4116,912,351 - 116,916,236 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04181,492,882 - 181,496,612 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44119,365,578 - 119,369,308 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14119,610,075 - 119,613,765 (-)NCBI
Celera4106,655,853 - 106,659,586 (-)NCBICelera
Cytogenetic Map4q34NCBI
Spr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542412,711,064 - 12,716,000 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542412,711,064 - 12,716,000 (-)NCBIChiLan1.0ChiLan1.0
SPR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A74,433,056 - 74,438,105 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A74,433,056 - 74,438,105 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A72,939,621 - 72,944,669 (+)NCBIMhudiblu_PPA_v0panPan3
SPR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11749,950,192 - 49,957,455 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1749,950,800 - 49,957,417 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1749,596,415 - 49,603,643 (-)NCBI
ROS_Cfam_1.01750,816,547 - 50,823,891 (-)NCBI
UMICH_Zoey_3.11749,832,663 - 49,840,008 (-)NCBI
UNSW_CanFamBas_1.01749,898,076 - 49,905,297 (-)NCBI
UU_Cfam_GSD_1.01750,458,363 - 50,465,721 (-)NCBI
SPR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl369,887,386 - 69,894,758 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1369,889,448 - 69,894,747 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2373,090,291 - 73,095,590 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11434,275,292 - 34,280,579 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1434,275,289 - 34,280,786 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604577,800,011 - 77,804,968 (+)NCBIVero_WHO_p1.0
Spr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624762729,294 - 734,761 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005322152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010001352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005322152   ⟹   XP_005322209
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629211,872,315 - 11,877,409 (-)NCBI
SpeTri2.0NW_00493649116,693,940 - 16,699,040 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005322209 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3267106 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005322209   ⟸   XM_005322152
- UniProtKB: I3MPM7 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015385 ENTREZGENE
Ensembl Protein ENSSTOP00000013776 ENTREZGENE
NCBI Gene Spr ENTREZGENE
UniProt I3MPM7 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-08 Spr  sepiapterin reductase    sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)  Symbol and/or name change 5135510 APPROVED