Elac2 (elaC ribonuclease Z 2) - Rat Genome Database

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Gene: Elac2 (elaC ribonuclease Z 2) Ictidomys tridecemlineatus
Analyze
Symbol: Elac2
Name: elaC ribonuclease Z 2
RGD ID: 12551222
Description: ENCODES a protein that exhibits tRNA-specific ribonuclease activity (ortholog); INVOLVED IN mitochondrial tRNA 3'-end processing (inferred); tRNA processing (inferred); PARTICIPATES IN tRNA maturation pathway; ASSOCIATED WITH combined oxidative phosphorylation deficiency 17 (ortholog); dilated cardiomyopathy (ortholog); genetic disease (ortholog); FOUND IN mitochondrial nucleoid (inferred); mitochondrion (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc phosphodiesterase ELAC protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560252,069,288 - 52,090,855 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365955,543,221 - 5,565,200 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365955,543,476 - 5,565,075 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Elac2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560252,069,288 - 52,090,855 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365955,543,221 - 5,565,200 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365955,543,476 - 5,565,075 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELAC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381712,991,612 - 13,018,027 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1712,991,612 - 13,018,065 (-)EnsemblGRCh38hg38GRCh38
GRCh371712,894,929 - 12,921,344 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361712,836,427 - 12,862,084 (-)NCBINCBI36Build 36hg18NCBI36
Build 341712,836,434 - 12,862,049NCBI
Celera1712,920,244 - 12,946,689 (-)NCBICelera
Cytogenetic Map17p12NCBI
HuRef1712,790,637 - 12,816,700 (-)NCBIHuRef
CHM1_11712,903,688 - 12,930,141 (-)NCBICHM1_1
T2T-CHM13v2.01712,899,079 - 12,925,488 (-)NCBIT2T-CHM13v2.0
Elac2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391164,869,856 - 64,892,906 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1164,869,864 - 64,892,895 (+)EnsemblGRCm39 Ensembl
GRCm381164,979,030 - 65,002,080 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1164,979,038 - 65,002,069 (+)EnsemblGRCm38mm10GRCm38
MGSCv371164,792,537 - 64,815,578 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361164,795,292 - 64,818,264 (+)NCBIMGSCv36mm8
Celera1171,914,934 - 71,938,052 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.42NCBI
Elac2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81050,131,449 - 50,154,755 (+)NCBIGRCr8
mRatBN7.21049,632,308 - 49,655,614 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1049,632,378 - 49,655,614 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1054,301,055 - 54,324,291 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01053,791,048 - 53,814,284 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01049,305,762 - 49,328,995 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01051,478,378 - 51,501,167 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1051,478,378 - 51,501,165 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01051,236,364 - 51,259,153 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41051,290,317 - 51,313,106 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11051,303,939 - 51,326,727 (+)NCBI
Celera1048,848,362 - 48,871,152 (+)NCBICelera
Cytogenetic Map10q24NCBI
Elac2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554674,406,824 - 4,427,780 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554674,406,947 - 4,428,769 (+)NCBIChiLan1.0ChiLan1.0
ELAC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21960,728,652 - 60,756,737 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11765,535,242 - 65,564,092 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01738,631,454 - 38,657,855 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11743,331,453 - 43,357,469 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1743,331,453 - 43,357,241 (+)Ensemblpanpan1.1panPan2
ELAC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1536,957,901 - 36,978,646 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl536,958,264 - 36,978,606 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha537,101,388 - 37,122,087 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0537,066,393 - 37,087,109 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl537,066,082 - 37,087,245 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1537,039,350 - 37,060,058 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0536,986,550 - 37,007,239 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0537,176,497 - 37,197,209 (-)NCBIUU_Cfam_GSD_1.0
ELAC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1257,206,600 - 57,238,444 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11257,206,596 - 57,238,438 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21260,096,837 - 60,116,251 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ELAC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11612,328,864 - 12,353,916 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1612,329,300 - 12,353,872 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660598,884,933 - 8,910,095 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elac2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624877850,726 - 874,831 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624877852,422 - 874,736 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000025346   ⟹   ENSSTOP00000019574
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365955,543,221 - 5,565,200 (-)Ensembl
RefSeq Acc Id: XM_013361767   ⟹   XP_013217221
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560252,069,288 - 52,090,855 (-)NCBI
SpeTri2.0NW_0049365955,543,476 - 5,565,075 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040269465   ⟹   XP_040125399
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560252,069,288 - 52,080,171 (-)NCBI
Protein Sequences
Protein RefSeqs XP_013217221 (Get FASTA)   NCBI Sequence Viewer  
  XP_040125399 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019574.1
GenBank Protein KAG3270016 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013217221   ⟸   XM_013361767
- Peptide Label: isoform X1
- UniProtKB: I3N5C8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040125399   ⟸   XM_040269465
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000019574   ⟸   ENSSTOT00000025346
Protein Domains
Metallo-beta-lactamase   tRNase Z endonuclease


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000006680 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000025346.2 UniProtKB/TrEMBL
Gene3D-CATH 3.60.15.10 UniProtKB/TrEMBL
InterPro Metallo-B-lactamas UniProtKB/TrEMBL
  RibonucZ/Hydroxyglut_hydro UniProtKB/TrEMBL
  RNZ2-like UniProtKB/TrEMBL
  tRNase_Z_dom UniProtKB/TrEMBL
NCBI Gene Elac2 ENTREZGENE
PANTHER ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 UniProtKB/TrEMBL
  ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 UniProtKB/TrEMBL
Pfam Lactamase_B_2 UniProtKB/TrEMBL
  Lactamase_B_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF56281 UniProtKB/TrEMBL
UniProt I3N5C8 ENTREZGENE, UniProtKB/TrEMBL