Tnfsf18 (TNF superfamily member 18) - Rat Genome Database

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Gene: Tnfsf18 (TNF superfamily member 18) Ictidomys tridecemlineatus
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Symbol: Tnfsf18
Name: TNF superfamily member 18
RGD ID: 12550985
Description: ENCODES a protein that exhibits identical protein binding (inferred); tumor necrosis factor receptor superfamily binding (inferred); INVOLVED IN activated CD4-positive, alpha-beta T cell proliferation (ortholog); positive regulation of interleukin-10 production (ortholog); positive regulation of interleukin-12 production (ortholog); ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); antithrombin III deficiency (ortholog); autoimmune lymphoproliferative syndrome (ortholog); FOUND IN cell surface (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tumor necrosis factor ligand superfamily member 18; tumor necrosis factor superfamily member 18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934496,652,746 - 96,661,551 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648114,499,577 - 14,508,017 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648114,499,495 - 14,508,074 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell surface  (IEA)
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Tnfsf18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934496,652,746 - 96,661,551 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648114,499,577 - 14,508,017 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648114,499,495 - 14,508,074 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFSF18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381173,039,202 - 173,050,941 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1173,039,202 - 173,050,941 (-)EnsemblGRCh38hg38GRCh38
GRCh371173,008,342 - 173,020,081 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,276,983 - 171,286,726 (-)NCBINCBI36Build 36hg18NCBI36
Build 341169,742,107 - 169,751,713NCBI
Celera1146,119,822 - 146,129,565 (-)NCBICelera
Cytogenetic Map1q25.1NCBI
HuRef1144,235,111 - 144,244,854 (-)NCBIHuRef
CHM1_11174,432,835 - 174,442,578 (-)NCBICHM1_1
T2T-CHM13v2.01172,397,315 - 172,409,046 (-)NCBIT2T-CHM13v2.0
Tnfsf18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391161,322,221 - 161,333,903 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1161,322,224 - 161,332,859 (+)EnsemblGRCm39 Ensembl
GRCm381161,494,657 - 161,505,290 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1161,494,655 - 161,505,290 (+)EnsemblGRCm38mm10GRCm38
MGSCv371163,424,788 - 163,435,421 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361163,331,332 - 163,341,967 (+)NCBIMGSCv36mm8
Celera1163,943,104 - 163,953,733 (+)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map169.75NCBI
Tnfsf18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81376,366,790 - 76,440,673 (+)NCBIGRCr8
mRatBN7.21373,833,478 - 73,907,249 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1373,831,252 - 73,843,169 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1376,412,930 - 76,422,686 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01377,710,263 - 77,720,018 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01374,970,140 - 74,979,895 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01379,378,412 - 79,388,687 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1379,378,733 - 79,388,498 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01384,270,937 - 84,282,548 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41377,137,045 - 77,145,251 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11377,151,151 - 77,159,439 (+)NCBI
Celera1373,609,947 - 73,620,222 (+)NCBICelera
Cytogenetic Map13q22NCBI
Tnfsf18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540613,391,162 - 13,402,479 (-)NCBIChiLan1.0ChiLan1.0
TNFSF18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2176,687,163 - 76,700,053 (+)NCBINHGRI_mPanPan1-v2
TNFSF18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1725,983,064 - 25,994,605 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl725,963,719 - 25,992,801 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha725,514,906 - 25,526,500 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0725,734,171 - 25,745,767 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl725,734,080 - 25,744,296 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1725,652,719 - 25,664,301 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0725,725,623 - 25,737,220 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0725,879,459 - 25,891,051 (+)NCBIUU_Cfam_GSD_1.0
TNFSF18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9115,448,973 - 115,460,950 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19115,447,438 - 115,460,649 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29127,140,943 - 127,151,861 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNFSF18
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12556,105,757 - 56,118,249 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2556,106,584 - 56,118,758 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605557,711,144 - 57,721,390 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnfsf18
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247718,711,017 - 8,722,539 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247718,711,093 - 8,722,518 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSSTOT00000010201   ⟹   ENSSTOP00000009153
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648114,499,577 - 14,508,017 (+)Ensembl
RefSeq Acc Id: XM_040277908   ⟹   XP_040133842
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934496,652,746 - 96,661,551 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040133842 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000009153.3
RefSeq Acc Id: XP_040133842   ⟸   XM_040277908
- UniProtKB: I3MF12 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000009153   ⟸   ENSSTOT00000010201


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010210 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010201.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.40 UniProtKB/TrEMBL
InterPro TNF_CS UniProtKB/TrEMBL
  TNFSF18 UniProtKB/TrEMBL
  Tumour_necrosis_fac-like_dom UniProtKB/TrEMBL
NCBI Gene Tnfsf18 ENTREZGENE
PANTHER PTHR15267 UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 18 UniProtKB/TrEMBL
PROSITE TNF_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF49842 UniProtKB/TrEMBL
UniProt I3MF12 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-08 Tnfsf18  TNF superfamily member 18    tumor necrosis factor superfamily member 18  Symbol and/or name change 5135510 APPROVED