Nudt6 (nudix hydrolase 6) - Rat Genome Database

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Gene: Nudt6 (nudix hydrolase 6) Ictidomys tridecemlineatus
Analyze
Symbol: Nudt6
Name: nudix hydrolase 6
RGD ID: 12549512
Description: ENCODES a protein that exhibits ADP-ribose diphosphatase activity (inferred); hydrolase activity (inferred); NAD binding (inferred); INVOLVED IN negative regulation of cell cycle (inferred); negative regulation of cell population proliferation (inferred); ASSOCIATED WITH genetic disease (ortholog); neurodevelopmental disorder with hearing loss, seizures, and brain abnormalities (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (inferred); mitochondrion (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nucleoside diphosphate-linked moiety X motif 6; nudix hydrolase 6, transcript variant X1; nudix hydrolase 6, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530165,164,147 - 65,191,211 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366621,928,656 - 1,953,692 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366621,929,104 - 1,939,297 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
mitochondrion  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Nudt6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530165,164,147 - 65,191,211 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366621,928,656 - 1,953,692 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366621,929,104 - 1,939,297 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUDT6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384122,892,577 - 122,922,968 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4122,888,697 - 122,922,968 (-)EnsemblGRCh38hg38GRCh38
GRCh374123,813,732 - 123,844,123 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364124,033,249 - 124,063,573 (-)NCBINCBI36Build 36hg18NCBI36
Build 344124,171,404 - 124,201,728NCBI
Celera4121,196,643 - 121,226,966 (-)NCBICelera
Cytogenetic Map4q28.1NCBI
HuRef4119,540,226 - 119,570,607 (-)NCBIHuRef
CHM1_14123,790,305 - 123,820,699 (-)NCBICHM1_1
T2T-CHM13v2.04126,196,685 - 126,227,087 (-)NCBIT2T-CHM13v2.0
Nudt6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39337,459,126 - 37,474,391 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl337,459,059 - 37,474,360 (-)EnsemblGRCm39 Ensembl
GRCm38337,404,982 - 37,420,242 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl337,404,910 - 37,420,211 (-)EnsemblGRCm38mm10GRCm38
MGSCv37337,303,906 - 37,318,512 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36337,596,533 - 37,611,139 (-)NCBIMGSCv36mm8
Celera337,279,832 - 37,294,433 (-)NCBICelera
Cytogenetic Map3BNCBI
cM Map318.46NCBI
Nudt6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82122,218,031 - 122,234,488 (-)NCBIGRCr8
mRatBN7.22120,289,908 - 120,306,197 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2120,290,847 - 120,306,230 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2126,853,694 - 126,869,041 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02124,966,200 - 124,981,547 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02119,595,156 - 119,610,504 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02124,134,301 - 124,149,824 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2124,134,307 - 124,149,636 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02143,741,978 - 143,757,855 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42123,947,307 - 123,962,639 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12123,897,078 - 123,912,401 (-)NCBI
Celera2115,237,481 - 115,252,817 (-)NCBICelera
Cytogenetic Map2q25NCBI
Nudt6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542817,823,642 - 17,843,558 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542817,823,994 - 17,840,380 (+)NCBIChiLan1.0ChiLan1.0
NUDT6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23120,669,730 - 120,699,792 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14120,935,554 - 120,965,604 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04115,070,782 - 115,100,841 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14126,215,190 - 126,245,586 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4126,215,197 - 126,245,060 (-)Ensemblpanpan1.1panPan2
NUDT6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11917,371,589 - 17,403,182 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1917,371,841 - 17,402,911 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1917,584,739 - 17,617,483 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01917,484,708 - 17,516,416 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1917,484,992 - 17,521,362 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11917,440,801 - 17,473,321 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01917,719,306 - 17,752,032 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01918,191,160 - 18,223,766 (+)NCBIUU_Cfam_GSD_1.0
NUDT6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8101,241,589 - 101,284,486 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18101,241,155 - 101,302,760 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28108,446,198 - 108,489,298 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NUDT6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1770,157,573 - 70,188,200 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl770,157,757 - 70,188,154 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603749,127,460 - 49,158,101 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nudt6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247773,321,376 - 3,342,089 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000026399   ⟹   ENSSTOP00000017957
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366621,928,656 - 1,953,692 (-)Ensembl
RefSeq Acc Id: XM_005336518   ⟹   XP_005336575
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530165,180,587 - 65,191,211 (+)NCBI
SpeTri2.0NW_0049366621,929,104 - 1,937,045 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021734061   ⟹   XP_021589736
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530165,180,038 - 65,191,211 (+)NCBI
SpeTri2.0NW_0049366621,929,104 - 1,939,297 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040293323   ⟹   XP_040149257
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530165,164,147 - 65,191,211 (+)NCBI
RefSeq Acc Id: XM_040293324   ⟹   XP_040149258
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530165,169,514 - 65,191,211 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005336575 (Get FASTA)   NCBI Sequence Viewer  
  XP_021589736 (Get FASTA)   NCBI Sequence Viewer  
  XP_040149257 (Get FASTA)   NCBI Sequence Viewer  
  XP_040149258 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000017957.2
GenBank Protein KAG3276219 (Get FASTA)   NCBI Sequence Viewer  
  KAG3276220 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005336575   ⟸   XM_005336518
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021589736   ⟸   XM_021734061
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040149257   ⟸   XM_040293323
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040149258   ⟸   XM_040293324
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000017957   ⟸   ENSSTOT00000026399
Protein Domains
Nudix hydrolase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020437 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000026399.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.630.30 UniProtKB/TrEMBL
  4.10.80.100 UniProtKB/TrEMBL
  Nucleoside Triphosphate Pyrophosphohydrolase UniProtKB/TrEMBL
InterPro Nudix_hydrolase UniProtKB/TrEMBL
  NUDIX_hydrolase-like_dom_sf UniProtKB/TrEMBL
  Nudix_hydrolase6-like UniProtKB/TrEMBL
  NUDIX_hydrolase_CS UniProtKB/TrEMBL
  NUDIX_hydrolase_dom UniProtKB/TrEMBL
  Pre-Nudix UniProtKB/TrEMBL
NCBI Gene Nudt6 ENTREZGENE
PANTHER NUCLEOSIDE DIPHOSPHATE-LINKED MOIETY X MOTIF 6 UniProtKB/TrEMBL
  PTHR13994 UniProtKB/TrEMBL
Pfam NUDIX UniProtKB/TrEMBL
  Nudix_hydro UniProtKB/TrEMBL
PRINTS GFGPROTEIN UniProtKB/TrEMBL
  NUDIXFAMILY UniProtKB/TrEMBL
PROSITE NUDIX UniProtKB/TrEMBL
  NUDIX_BOX UniProtKB/TrEMBL
Superfamily-SCOP SSF55811 UniProtKB/TrEMBL
UniProt I3N0R1_ICTTR UniProtKB/TrEMBL