Plekhh1 (pleckstrin homology, MyTH4 and FERM domain containing H1) - Rat Genome Database

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Gene: Plekhh1 (pleckstrin homology, MyTH4 and FERM domain containing H1) Ictidomys tridecemlineatus
Analyze
Symbol: Plekhh1
Name: pleckstrin homology, MyTH4 and FERM domain containing H1
RGD ID: 12544230
Description: ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); Leber congenital amaurosis 13 (ortholog); FOUND IN cytoskeleton (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology domain-containing family H member 1; pleckstrin homology, MyTH4 and FERM domain containing H1, transcript variant X1; pleckstrin homology, MyTH4 and FERM domain containing H1, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864063,220,352 - 63,270,563 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649510,929,656 - 10,969,350 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649510,921,136 - 10,971,349 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoskeleton  (IEA)

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Plekhh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864063,220,352 - 63,270,563 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649510,929,656 - 10,969,350 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649510,921,136 - 10,971,349 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381467,533,290 - 67,589,612 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1467,533,290 - 67,589,612 (+)EnsemblGRCh38hg38GRCh38
GRCh371468,000,007 - 68,056,329 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361467,069,761 - 67,126,008 (+)NCBINCBI36Build 36hg18NCBI36
Celera1448,059,079 - 48,115,320 (+)NCBICelera
Cytogenetic Map14q24.1NCBI
HuRef1448,169,751 - 48,225,996 (+)NCBIHuRef
CHM1_11467,938,650 - 67,994,902 (+)NCBICHM1_1
T2T-CHM13v2.01461,740,406 - 61,796,732 (+)NCBIT2T-CHM13v2.0
Plekhh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391279,075,937 - 79,128,429 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1279,075,937 - 79,128,429 (+)EnsemblGRCm39 Ensembl
GRCm381279,029,163 - 79,081,655 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1279,029,163 - 79,081,655 (+)EnsemblGRCm38mm10GRCm38
MGSCv371280,130,150 - 80,182,642 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361279,922,250 - 80,001,220 (+)NCBIMGSCv36mm8
Celera1280,493,584 - 80,546,131 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1235.51NCBI
Plekhh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86103,572,304 - 103,621,729 (+)NCBIGRCr8
mRatBN7.2697,839,288 - 97,888,712 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl697,839,288 - 97,888,709 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx698,268,836 - 98,318,136 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0698,567,990 - 98,617,288 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0697,954,925 - 98,003,962 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06102,215,424 - 102,264,345 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6102,215,603 - 102,262,417 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06111,585,028 - 111,633,995 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46101,664,129 - 101,714,245 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16101,621,814 - 101,743,779 (+)NCBI
Celera696,226,252 - 96,275,106 (+)NCBICelera
Cytogenetic Map6q24NCBI
Plekhh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554662,618,585 - 2,653,771 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554662,616,627 - 2,653,804 (-)NCBIChiLan1.0ChiLan1.0
PLEKHH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21568,641,414 - 68,697,820 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11467,857,929 - 67,914,332 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01448,111,017 - 48,167,541 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11466,989,464 - 67,045,677 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1466,989,471 - 67,045,677 (+)Ensemblpanpan1.1panPan2
PLEKHH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1841,508,866 - 41,560,054 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl841,508,740 - 41,559,932 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha841,201,689 - 41,253,144 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0841,737,162 - 41,788,663 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl841,744,542 - 41,785,651 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1841,355,953 - 41,407,440 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0841,429,613 - 41,481,066 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0841,789,019 - 41,840,536 (+)NCBIUU_Cfam_GSD_1.0
PLEKHH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12444,781,699 - 44,835,802 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2444,790,362 - 44,835,351 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605333,011,773 - 33,067,736 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekhh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473433,413,087 - 33,449,932 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473433,411,271 - 33,456,003 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000000247   ⟹   ENSSTOP00000000219
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493649510,929,656 - 10,969,350 (+)Ensembl
RefSeq Acc Id: XM_005322813   ⟹   XP_005322870
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864063,220,352 - 63,270,563 (-)NCBI
SpeTri2.0NW_00493649510,921,136 - 10,971,349 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021724827   ⟹   XP_021580502
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864063,220,352 - 63,270,563 (-)NCBI
SpeTri2.0NW_00493649510,921,136 - 10,971,349 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005322870 (Get FASTA)   NCBI Sequence Viewer  
  XP_021580502 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000000219.3
GenBank Protein KAG3261252 (Get FASTA)   NCBI Sequence Viewer  
  KAG3261253 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005322870   ⟸   XM_005322813
- Peptide Label: isoform X1
- UniProtKB: I3LW84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021580502   ⟸   XM_021724827
- Peptide Label: isoform X2
- UniProtKB: I3LW84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000000219   ⟸   ENSSTOT00000000247
Protein Domains
FERM   MyTH4   PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000245 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000247.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  1.25.40.530 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  MyTH4_dom UniProtKB/TrEMBL
  MyTH4_dom_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene Plekhh1 ENTREZGENE
PANTHER PLEKHH PROTEIN UniProtKB/TrEMBL
  PTHR22903:SF4 UniProtKB/TrEMBL
Pfam FERM_M UniProtKB/TrEMBL
  MyTH4 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
PROSITE FERM_3 UniProtKB/TrEMBL
  MYTH4 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
SMART B41 UniProtKB/TrEMBL
  MyTH4 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47031 UniProtKB/TrEMBL
UniProt I3LW84 ENTREZGENE, UniProtKB/TrEMBL