Pxn (paxillin) - Rat Genome Database

Name: Pxn
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Pxn (paxillin) Ictidomys tridecemlineatus

Analyze

Symbol:

Pxn

Name:

paxillin

RGD ID:

12542767

Description:

ENCODES a protein that exhibits beta-catenin binding (ortholog); BH4 domain binding (ortholog); integrin binding (ortholog); INVOLVED IN branching morphogenesis of an epithelial tube (ortholog); cell migration (ortholog); cellular response to reactive oxygen species (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; insulin-like growth factor signaling pathway; integrin mediated signaling pathway; ASSOCIATED WITH Experimental Melanoma (ortholog); genetic disease (ortholog); lung non-small cell carcinoma (ortholog); FOUND IN cell leading edge (ortholog); cell-cell junction (ortholog); cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC110599274; paxillin, transcript variant X1; paxillin, transcript variant X2; paxillin, transcript variant X3; paxillin, transcript variant X4; uncharacterized LOC110599274; uncharacterized protein LOC110599274

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PXN (paxillin)	NCBI	Ortholog
Mus musculus (house mouse):	Pxn (paxillin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Pxn (paxillin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pxn (paxillin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PXN (paxillin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PXN (paxillin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PXN (paxillin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PXN (paxillin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pxn (paxillin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	146,161,497 - 146,210,393 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936668	660,415 - 709,282 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Melanoma (ISO)

genetic disease (ISO)

lung non-small cell carcinoma (ISO)

Neoplasm Metastasis (ISO)

Neoplastic Cell Transformation (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

branching morphogenesis of an epithelial tube (ISO)

cell migration (ISO)

cellular response to reactive oxygen species (ISO)

cytoskeleton organization (ISO)

endothelial cell migration (IEA)

focal adhesion assembly (ISO)

growth hormone receptor signaling pathway (ISO)

integrin-mediated signaling pathway (ISO)

lamellipodium assembly (ISO)

positive regulation of angiogenesis (ISO)

positive regulation of stress fiber assembly (ISO)

regulation of cell shape (ISO)

response to peptide (ISO)

substrate adhesion-dependent cell spreading (IEA,ISO)

transforming growth factor beta receptor signaling pathway (IEA)

Cellular Component

anchoring junction (IEA)

cell leading edge (ISO)

cell-cell junction (ISO)

cytoplasm (IEA)

cytoskeleton (IEA)

cytosol (ISO)

focal adhesion (IEA,ISO)

lamellipodium (ISO)

plasma membrane (ISO)

stress fiber (ISO)

Molecular Function

beta-catenin binding (ISO)

BH4 domain binding (ISO)

integrin binding (ISO)

MAP-kinase scaffold activity (ISO)

metal ion binding (IEA)

neuropilin binding (ISO)

protein binding (ISO)

protein kinase binding (ISO)

protein phosphatase binding (ISO)

protein-containing complex binding (ISO)

vinculin binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

ephrin - ephrin receptor bidirectional signaling axis (ISO)

insulin-like growth factor signaling pathway (ISO)

integrin mediated signaling pathway (ISO)

mTOR signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Pxn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	146,161,497 - 146,210,393 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936668	660,415 - 709,282 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PXN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	120,210,447 - 120,265,730 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	120,210,439 - 120,265,771 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	120,648,250 - 120,703,533 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	119,132,640 - 119,187,892 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	119,110,976 - 119,166,229	NCBI
Celera	12	120,281,352 - 120,336,672 (-)	NCBI		Celera
Cytogenetic Map	12	q24.23	NCBI
HuRef	12	117,656,442 - 117,711,723 (-)	NCBI		HuRef
CHM1_1	12	120,616,253 - 120,671,571 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	120,197,626 - 120,252,894 (-)	NCBI		T2T-CHM13v2.0

Pxn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	115,630,035 - 115,694,046 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	115,644,735 - 115,694,046 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	115,491,970 - 115,555,987 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	115,506,676 - 115,555,987 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	115,956,711 - 116,005,995 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	115,767,751 - 115,815,656 (+)	NCBI		MGSCv36	mm8
Celera	5	112,606,134 - 112,661,101 (+)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	56.1	NCBI

Pxn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	46,721,546 - 46,768,706 (-)	NCBI		GRCr8
mRatBN7.2	12	41,060,791 - 41,107,952 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	41,060,791 - 41,107,931 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	42,228,092 - 42,275,199 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	42,841,747 - 42,888,851 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	41,902,292 - 41,949,397 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	46,797,953 - 46,845,107 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	46,797,954 - 46,845,080 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	48,595,399 - 48,642,177 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	42,322,193 - 42,370,507 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	42,185,581 - 42,233,895 (-)	NCBI
Celera	12	42,684,240 - 42,731,375 (-)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

Pxn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	11,388,378 - 11,403,082 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955455	11,387,140 - 11,401,178 (+)	NCBI	ChiLan1.0	ChiLan1.0

PXN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	128,272,300 - 128,327,525 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	128,268,677 - 128,323,899 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	117,785,614 - 117,840,816 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	121,160,295 - 121,200,695 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	121,160,295 - 121,176,667 (-)	Ensembl	panpan1.1		panPan2

PXN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	16,157,231 - 16,224,028 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	16,159,025 - 16,184,820 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	16,161,797 - 16,210,046 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	16,424,969 - 16,473,447 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	16,424,971 - 16,473,427 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	16,385,989 - 16,434,224 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	16,463,118 - 16,511,352 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	16,504,096 - 16,552,543 (-)	NCBI		UU_Cfam_GSD_1.0

PXN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	40,227,895 - 40,278,734 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	40,227,894 - 40,278,785 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

PXN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	115,560,859 - 115,619,093 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	115,560,662 - 115,619,029 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	129,487,668 - 129,546,391 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pxn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	13,370,243 - 13,435,714 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	13,371,128 - 13,435,619 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005336815	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005336816	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013363564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040289398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040289399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040289400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040289401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040289402	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040289403	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040289404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040289405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005336816 ⟹ XP_005336873

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	146,161,504 - 146,210,393 (+)	NCBI
SpeTri2.0	NW_004936668	660,415 - 709,282 (+)	NCBI

Sequence:

show sequence

GCGCGTTCCGTTCCGGGCCAACGCTGGCGGCGGAAAAGTTGCCGGGCGGAGAGGAGCAGCCCCG
GGACGGGCAGAGAGCGCGACGCGGAGCCGGCTCCCGGCCCTGGCTGCCCCGCCATGGACGACCT
CGACGCCCTGCTGGCAGACTTGGAGTCCACCACCTCCCACATCTCCAAGCGGCCTGTGTTTTTG
TCCGAGGAGCCCCCCTACTCCTACCCAACTGGAAACCACACCTACCAGGAGATTGCAGTGCCAC
CCCCTGTCCCTCCACCCCCATCAAGCGAGGCCCTCAATGGCACAGTCCTTGACCCCTTAGACCA
GTGGCAGTCCAGTGGCTCCCGACTCATTCACCAGCAGCCTCCATCCCCATCACCTGTGTACGGC
TCCAGTGCCAAAACTTCCGGTGCCTCCAACCCCCAGGACGGTGTTGGTTCTCCGTGCTCACGAG
CAAGTGAGGAGGAGCACGTCTACAGCTTCCCCAACAAGCAGAAGTCAGCCGAGCCTTCACCCAC
CGTAATGAGCTCCTCCCTGGGCAGCAACCTTTCTGAACTTGACCGTCTGCTGCTAGAACTGAAT
GCTGTGCAGCATAATTCTCCAGGCTTCCCTGCAGAGGAGACCAACACAAGCCCTCCACTCCCGG
GGGCCCTGAGCCCTCACTATGGCATCCCAGAGAACAACAGTCCCGTGGGAGTCAAAGCTGGGCC
CCTGACAAAAGAGAAGCCCAAGCGGAACGGGAGCCGGGGCCTGGAGGACGTTCGGCCTAGTGTG
GAGAGTCTCTTGGATGAACTGGAGAGCTCTGTGCCTAGCCCTGTCCCGGCCATCACTGTGAACC
AGGGCGAGATGAGCAGCCCACAGAGAGTCACCTCCAGCCAGCAGCAGACGCGCATCTCGGCCTC
CTCTGCCACCAGGGAGCTGGACGAGCTGATGGCCTCGCTGTCAGATTTTAAGTTCATGGCTCAG
GGGAAGACTGGGAGCAGCTCACCCCCCGGGGGACCCCCAAAGCCTGGGAGCCAGCTGGACAGCA
TGCTGGGGAGCCTACAGTCTGACCTGAACAAGTTGGGGGTCGCCACGGTTGCCAAAGGAGTCTG
CGGGGCCTGCAAGAAGCCCATCGCCGGGCAGGTTGTGACTGCCATGGGGAAGACTTGGCACCCT
GAACACTTTGTCTGCACCCACTGCCAGGAAGAGATCGGATCCCGGAACTTCTTCGAGCGGGATG
GACAGCCCTACTGTGAAAAGGACTATCACAACCTCTTCTCCCCACGCTGCTACTACTGCAACGG
TCCCATCCTGGATAAAGTGGTGACGGCCCTTGACCGGACTTGGCATCCTGAGCACTTCTTTTGT
GCCCAATGTGGAGCCTTCTTTGGTCCTGAAGGGTTCCATGAGAAGGATGGCAAGGCCTATTGCC
GAAAGGATTATTTTGACATGTTTGCGCCCAAGTGTGGTGGCTGTGCCCGGGCCATCCTGGAGAA
CTACATCTCAGCCCTCAACACCCTTTGGCATCCTGAGTGCTTTGTGTGCCGGGAATGCTTCACA
CCTTTCATCAACGGCAGCTTCTTTGAGCATGACGGGCAGCCGTACTGCGAGGTGCACTACCATG
AGCGGCGCGGCTCGCTGTGCTCTGGCTGCCAGAAGCCCATCACGGGGCGCTGCATCACCGCCAT
GGCCAAGAAGTTCCACCCGGAGCACTTTGTCTGTGCCTTCTGCCTCAAGCAGCTGAACAAGGGC
ACCTTCAAGGAGCAAAATGACAAGCCTTACTGCCAGAACTGCTTCCTCAAGCTCTTCTGCTAGG
CGTCCCTTCCCCAGCCCCGCCGCCCTGACTGCTACTGTGACCCAGAGACGTGGAAACTGGAACC
CTCATCCTCAGCTGGCACAGGATGGGACAAGGGGCATGGGGGTCCTGTGTGCTTCTCTAGCCCC
CACCAAAGCCTTGGGCCTCCCTTCTCTTCCTACAGCTCTCCCCAGGCTGCCCACTCCTCATCCT
CCTGGAGGTGGAGGCTGGGGGCTCCATCCCACCTGACATGTGTCCCCATGAACCTGCCCGGCCT
GGCCAGCAACCCACACTGGAGCCATCTTGTACTCCGATTTCAGCAGCAGAGCTTGGGAGGGAAG
GGCCGGCAGGGTTACATGGAGTCTCTTTTTATCCTTATCCCCTCAAACCACAGTCTAACTGTCC
TGAGAGAATTGGGGGGTTCCCTGCTCCCTCCAAACAATGCCAGCATAAACCCATCCATCCAAGG
GTGGAAGTGCTCAAGGGACTGCAGGTTTCTTGGGCTCTCGCCTTCCAGTCTCCCCAGGCCTGGG
TGACTGTCCCCTTTCCCAACTGCCTCTTTTATAACTGCTCCAGTTCTACTGAGAAAGGCCTCTC
CAGCAATAATGTTTTATAGCCACTTCCTCCATCTCCCAGGACAGCACCCATGGGGAGTGTCGCC
TGGGCCTGGACACTGTACCGACTTTGATAGATTTCTACACTGAGGTTTGAATTATGTCACCCAA
GTTGCTTTTATTTCTCGATACAAGATGATTTTGAAGAGATTTTAAAGACGTTCCCTTTTATATT
CTCCTCCTCCTCATCCACTGCTGCTGGTCCTGTCAGTGACCATGGCTTTGGCTTGGAGTTTGCT
TTGTACCGGGTCGGGGAGCAATTTGTATTTTATTTTTTTCTTGGCGTAAGCAGGTGAACTGGGA
GCAGCTCTGTGACTCTTCTTCTGTAACTTCATGGCTCACCAGGACTGTTTTATAAACTGCTGTA
TTTTGAAACCCCTTCCTTTCTGCCCAGGCCAGCAGCTCTTAATTCAAACTGGCCTGAGTGTGTC
TGACCCTTTGGGACCTGGAATTCTGAACCTCATCTGTCCTGTTCCTAAGGGAGGAGAAGGGGAA
AGTATACTTGGGGGGCTGCTTCCTGTCTGAGTAGGAGCTTTTTGGCAACAAAGAACCCACTGAA
CATTCTCGGCCTCCTCACTACTTCTCCAGGGCTTTCTCCTGTCTTCTCAGGAAAAATTGGTTTC
TGATTTTGACCATGAAGACCATAAATGTCTCTTTGGTCTTATTGATTCCACTGGGCATATTCCT
TCCTCAAATTTCCTGCCCTCCCTGGAGACTGGCACAGGTTCCTCCCCCTTTACAGGGGTGATTG
GCACTTCAATTTGGGAAGAAGGCCCCAGGTTGGTGCAAGGGAGCCTGAGAGGATTTGGGGCAGA
GGGACAGGGTCCTGCTGAAGCGACAGGAAGCCCCAGAGCTCTTTCCCAGGATAAAGCAGGAGCA
GGCAGGCCTGGGTTTCCTGGTCAAGGGCAAGGGACCCCAGAGTGGTCTACTGGGAGGGATTCAG
ACCGGTCCACAGGCCTCCCAGCACAGGCTGAGTATGCTGCGGTCCCAGAAGAGGATCTTTTCCT
CTGGGCTGGCCTGGGAGCTGCCTAGGTCTGGGAGGTCCTCCAAAGGTCTGACATCTCCACGCCC
ACCACAGGCCTTACTGCTCTGTTTACAATGACCCACTCCAGGTCCCTCCCCAAGAGGGACTGGG
GTTTCTGGGAGTCAACCCTCTGGGTCAATGGTTATTTGATCATTTGATTTTTTTTTTTCTCTAT
AAACTTCTAACCTGGCCTTTTCCATTTCAATTCCTGTGATTCATGCCAATAAAGTGTGCCATTA
TTTTCA

hide sequence

RefSeq Acc Id:

XM_040289398 ⟹ XP_040145332

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	146,197,072 - 146,210,393 (+)	NCBI

RefSeq Acc Id:

XM_040289399 ⟹ XP_040145333

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	146,161,497 - 146,210,393 (+)	NCBI

RefSeq Acc Id:

XM_040289400 ⟹ XP_040145334

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	146,197,072 - 146,210,393 (+)	NCBI

RefSeq Acc Id:

XM_040289401 ⟹ XP_040145335

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	146,197,072 - 146,210,393 (+)	NCBI

RefSeq Acc Id:

XM_040289402 ⟹ XP_040145336

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	146,196,694 - 146,210,393 (+)	NCBI

RefSeq Acc Id:

XM_040289403 ⟹ XP_040145337

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	146,196,694 - 146,210,393 (+)	NCBI

RefSeq Acc Id:

XM_040289404 ⟹ XP_040145338

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	146,182,587 - 146,210,393 (+)	NCBI

RefSeq Acc Id:

XM_040289405 ⟹ XP_040145339

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	146,162,430 - 146,210,393 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005336873	(Get FASTA)	NCBI Sequence Viewer
	XP_040145332	(Get FASTA)	NCBI Sequence Viewer
	XP_040145333	(Get FASTA)	NCBI Sequence Viewer
	XP_040145334	(Get FASTA)	NCBI Sequence Viewer
	XP_040145335	(Get FASTA)	NCBI Sequence Viewer
	XP_040145336	(Get FASTA)	NCBI Sequence Viewer
	XP_040145337	(Get FASTA)	NCBI Sequence Viewer
	XP_040145338	(Get FASTA)	NCBI Sequence Viewer
	XP_040145339	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000012629.3
GenBank Protein	KAG3278911	(Get FASTA)	NCBI Sequence Viewer
	KAG3278912	(Get FASTA)	NCBI Sequence Viewer
	KAG3278913	(Get FASTA)	NCBI Sequence Viewer
	KAG3278914	(Get FASTA)	NCBI Sequence Viewer
	KAG3278915	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005336873 ⟸ XM_005336816

- Peptide Label:

isoform X7

- Sequence:

show sequence

MDDLDALLADLESTTSHISKRPVFLSEEPPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTVLD
PLDQWQSSGSRLIHQQPPSPSPVYGSSAKTSGASNPQDGVGSPCSRASEEEHVYSFPNKQKSAE
PSPTVMSSSLGSNLSELDRLLLELNAVQHNSPGFPAEETNTSPPLPGALSPHYGIPENNSPVGV
KAGPLTKEKPKRNGSRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSSQQQTR
ISASSATRELDELMASLSDFKFMAQGKTGSSSPPGGPPKPGSQLDSMLGSLQSDLNKLGVATVA
KGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCY
YCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARA
ILENYISALNTLWHPECFVCRECFTPFINGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRC
ITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC

hide sequence

RefSeq Acc Id:	XP_040145333 ⟸ XM_040289399
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_040145339 ⟸ XM_040289405
- Peptide Label:	isoform X8
- UniProtKB:	I3MM96 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040145338 ⟸ XM_040289404
- Peptide Label:	isoform X8
- UniProtKB:	I3MM96 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040145336 ⟸ XM_040289402
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_040145337 ⟸ XM_040289403
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_040145332 ⟸ XM_040289398
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_040145334 ⟸ XM_040289400
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_040145335 ⟸ XM_040289401
- Peptide Label:	isoform X4

Protein Domains

LIM zinc-binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000014093	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000014096.3	UniProtKB/TrEMBL
Gene3D-CATH	Cysteine Rich Protein	UniProtKB/TrEMBL
InterPro	Paxillin_TGFB1I1_LIM_dom1	UniProtKB/TrEMBL
	Tgfb1i1/Leupaxin/TGFB1I1	UniProtKB/TrEMBL
	Znf_LIM	UniProtKB/TrEMBL
NCBI Gene	Pxn	ENTREZGENE
PANTHER	PAXILLIN-RELATED	UniProtKB/TrEMBL
	PTHR24216:SF11	UniProtKB/TrEMBL
Pfam	LIM	UniProtKB/TrEMBL
	Paxillin	UniProtKB/TrEMBL
PIRSF	Leupaxin	UniProtKB/TrEMBL
PRINTS	PAXILLIN	UniProtKB/TrEMBL
PROSITE	LIM_DOMAIN_1	UniProtKB/TrEMBL
	LIM_DOMAIN_2	UniProtKB/TrEMBL
SMART	LIM	UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/TrEMBL
UniProt	I3MM96	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-25	Pxn	paxillin	LOC110599274	uncharacterized LOC110599274	Data merged from RGD:13098025	737654	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)