Atp1b4 (ATPase Na+/K+ transporting family member beta 4) - Rat Genome Database

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Gene: Atp1b4 (ATPase Na+/K+ transporting family member beta 4) Ictidomys tridecemlineatus
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Symbol: Atp1b4
Name: ATPase Na+/K+ transporting family member beta 4
RGD ID: 12542689
Description: INVOLVED IN inorganic cation transmembrane transport (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); Danon disease (ortholog); FOUND IN chromatin (ortholog); nuclear envelope (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X91,263,951 - 91,338,728 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364799,650,598 - 9,666,782 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364799,648,315 - 9,666,782 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
alfentanil pharmacodynamics pathway  (ISO)
amiloride pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
bendroflumethiazide pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bumetanide pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
chlorothiazide pharmacodynamics pathway  (ISO)
chlorthalidone pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
cystinuria pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
eplerenone pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
etacrynic acid pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
furosemide pharmacodynamics pathway  (ISO)
Hartnup disease pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrochlorothiazide pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydroflumethiazide pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
iminoglycinuria pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
lactose degradation pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
lysinuric protein intolerance pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
metolazone pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
spironolactone pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
torasemide pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)
trehalose degradation pathway  (ISO)
triamterene pharmacodynamics pathway  (ISO)
trichlormethiazide pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Atp1b4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X91,263,951 - 91,338,728 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364799,650,598 - 9,666,782 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364799,648,315 - 9,666,782 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP1B4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X120,362,089 - 120,383,237 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX120,362,085 - 120,383,249 (+)EnsemblGRCh38hg38GRCh38
GRCh37X119,495,944 - 119,517,092 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X119,379,995 - 119,400,254 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X119,277,848 - 119,298,104NCBI
CeleraX119,961,554 - 119,982,718 (+)NCBICelera
Cytogenetic MapXq24NCBI
HuRefX108,947,429 - 108,968,212 (+)NCBIHuRef
CHM1_1X119,407,371 - 119,428,792 (+)NCBICHM1_1
T2T-CHM13v2.0X118,737,159 - 118,758,401 (+)NCBIT2T-CHM13v2.0
Atp1b4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X37,404,999 - 37,425,661 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX37,405,061 - 37,425,646 (+)EnsemblGRCm39 Ensembl
GRCm38X38,316,122 - 38,336,784 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX38,316,184 - 38,336,769 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X35,669,444 - 35,689,890 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X34,560,894 - 34,581,340 (+)NCBIMGSCv36mm8
CeleraX25,962,988 - 25,983,444 (+)NCBICelera
Cytogenetic MapXA3.3NCBI
cM MapX22.58NCBI
Atp1b4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X121,952,923 - 121,974,146 (+)NCBIGRCr8
mRatBN7.2X117,087,284 - 117,108,023 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX117,057,423 - 117,108,020 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX119,186,440 - 119,207,156 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X122,755,585 - 122,776,301 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X120,301,410 - 120,322,134 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X124,631,544 - 124,652,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX124,631,881 - 124,652,975 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X124,717,191 - 124,738,098 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X7,025,531 - 7,046,207 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X7,031,086 - 7,051,763 (-)NCBI
CeleraX116,305,018 - 116,325,839 (+)NCBICelera
Cytogenetic MapXq35NCBI
Atp1b4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555721,507,290 - 1,524,422 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555721,507,290 - 1,524,359 (-)NCBIChiLan1.0ChiLan1.0
ATP1B4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X119,908,970 - 119,929,862 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X119,912,574 - 119,933,466 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X109,633,770 - 109,654,662 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X119,820,695 - 119,841,598 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX119,820,695 - 119,841,598 (+)Ensemblpanpan1.1panPan2
ATP1B4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X92,347,443 - 92,368,206 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX92,347,684 - 92,365,341 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX78,379,094 - 78,399,754 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X94,088,087 - 94,108,743 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX94,088,217 - 94,105,868 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X91,543,107 - 91,563,771 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X93,299,931 - 93,320,587 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X93,081,031 - 93,101,689 (+)NCBIUU_Cfam_GSD_1.0
ATP1B4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX98,514,305 - 98,535,149 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X98,514,286 - 98,535,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X112,773,772 - 112,794,615 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ATP1B4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606533,077,794 - 33,098,919 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp1b4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624931234,103 - 255,189 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624931234,184 - 255,154 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000002312   ⟹   ENSSTOP00000002067
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364799,650,598 - 9,666,782 (-)Ensembl
RefSeq Acc Id: XM_005319355   ⟹   XP_005319412
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X91,320,649 - 91,338,728 (+)NCBI
SpeTri2.0NW_0049364799,648,315 - 9,666,782 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040284933   ⟹   XP_040140867
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X91,320,648 - 91,338,728 (+)NCBI
RefSeq Acc Id: XM_040284936   ⟹   XP_040140870
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X91,263,951 - 91,338,728 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005319412 (Get FASTA)   NCBI Sequence Viewer  
  XP_040140867 (Get FASTA)   NCBI Sequence Viewer  
  XP_040140870 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000002067.3
GenBank Protein KAG3272836 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005319412   ⟸   XM_005319355
- Peptide Label: isoform X2
- UniProtKB: I3M065 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040140870   ⟸   XM_040284936
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040140867   ⟸   XM_040284933
- Peptide Label: isoform X1
Ensembl Acc Id: ENSSTOP00000002067   ⟸   ENSSTOT00000002312


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002312 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000002312.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1660 UniProtKB/TrEMBL
InterPro Na/K_ATPase_sub_beta UniProtKB/TrEMBL
  Na/K_ATPase_sub_beta_sf UniProtKB/TrEMBL
NCBI Gene Atp1b4 ENTREZGENE
PANTHER PROTEIN ATP1B4 UniProtKB/TrEMBL
  PTHR11523 UniProtKB/TrEMBL
Pfam Na_K-ATPase UniProtKB/TrEMBL
PROSITE ATPASE_NA_K_BETA_1 UniProtKB/TrEMBL
  ATPASE_NA_K_BETA_2 UniProtKB/TrEMBL
UniProt I3M065 ENTREZGENE, UniProtKB/TrEMBL