Ilrun (inflammation and lipid regulator with UBA-like and NBR1-like domains) - Rat Genome Database

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Gene: Ilrun (inflammation and lipid regulator with UBA-like and NBR1-like domains) Ictidomys tridecemlineatus
Analyze
Symbol: Ilrun
Name: inflammation and lipid regulator with UBA-like and NBR1-like domains
RGD ID: 12541098
Description: ENCODES a protein that exhibits ubiquitin binding (inferred); INVOLVED IN macroautophagy (inferred); negative regulation of defense response to virus (inferred); negative regulation of protein localization to nucleus (inferred); ASSOCIATED WITH proteasome-associated autoinflammatory syndrome 1 (ortholog); FOUND IN centrosome (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chromosome unknown C6orf106 homolog; chromosome unknown open reading frame, human C6orf106; CUNH6orf106; LOC101970985; uncharacterized protein C6orf106 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494639,424,067 - 39,511,774 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647624,448,350 - 24,536,196 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647624,448,402 - 24,536,163 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ilrun
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494639,424,067 - 39,511,774 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647624,448,350 - 24,536,196 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647624,448,402 - 24,536,163 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ILRUN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38634,587,288 - 34,696,767 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl634,587,288 - 34,696,859 (-)EnsemblGRCh38hg38GRCh38
GRCh37634,555,065 - 34,664,544 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36634,663,043 - 34,772,603 (-)NCBINCBI36Build 36hg18NCBI36
Celera636,109,394 - 36,219,085 (-)NCBICelera
Cytogenetic Map6p21.31NCBI
HuRef634,277,695 - 34,387,079 (-)NCBIHuRef
CHM1_1634,558,029 - 34,667,828 (-)NCBICHM1_1
T2T-CHM13v2.0634,411,143 - 34,520,743 (-)NCBIT2T-CHM13v2.0
Ilrun
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391727,970,206 - 28,039,516 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1727,970,209 - 28,039,622 (-)EnsemblGRCm39 Ensembl
GRCm381727,751,232 - 27,820,542 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1727,751,235 - 27,820,648 (-)EnsemblGRCm38mm10GRCm38
MGSCv371727,888,180 - 27,957,487 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361727,481,414 - 27,548,131 (-)NCBIMGSCv36mm8
Celera1728,303,533 - 28,372,972 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1714.59NCBI
Ilrun
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8205,811,721 - 5,878,082 (-)NCBIGRCr8
mRatBN7.2205,809,931 - 5,876,197 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl205,809,936 - 5,876,012 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx206,522,583 - 6,588,605 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0205,884,372 - 5,950,402 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0206,364,082 - 6,430,193 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0207,331,321 - 7,397,588 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl207,331,326 - 7,397,448 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0209,533,329 - 9,599,034 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,965,992 - 6,033,724 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera207,371,306 - 7,437,251 (-)NCBICelera
Cytogenetic Map20p12NCBI
Ilrun
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554372,694,945 - 2,769,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554372,697,998 - 2,769,998 (-)NCBIChiLan1.0ChiLan1.0
ILRUN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1123,861,063 - 3,955,356 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl123,862,477 - 3,955,348 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha123,876,763 - 3,970,773 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0124,196,212 - 4,290,402 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl124,197,909 - 4,290,436 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1123,857,654 - 3,951,847 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0123,939,003 - 4,033,002 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0124,037,998 - 4,132,485 (-)NCBIUU_Cfam_GSD_1.0
ILRUN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl730,562,987 - 30,667,146 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1730,561,744 - 30,667,115 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2735,318,373 - 35,410,399 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.2735,167,561 - 35,188,220 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ILRUN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11737,402,940 - 37,555,871 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1737,402,966 - 37,516,822 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604434,506,953 - 34,624,366 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ilrun
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475422,613,396 - 22,694,022 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000028150   ⟹   ENSSTOP00000014941
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647624,448,350 - 24,536,196 (+)Ensembl
RefSeq Acc Id: XM_005318786   ⟹   XP_005318843
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494639,424,067 - 39,511,771 (-)NCBI
SpeTri2.0NW_00493647624,448,402 - 24,536,163 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005318788   ⟹   XP_005318845
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494639,427,067 - 39,511,771 (-)NCBI
SpeTri2.0NW_00493647624,448,424 - 24,536,163 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040282497   ⟹   XP_040138431
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494639,424,067 - 39,511,774 (-)NCBI
RefSeq Acc Id: XM_040282498   ⟹   XP_040138432
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494639,433,063 - 39,511,772 (-)NCBI
RefSeq Acc Id: XM_040282499   ⟹   XP_040138433
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494639,439,701 - 39,511,772 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005318845   ⟸   XM_005318788
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_005318843   ⟸   XM_005318786
- Peptide Label: isoform X3
- UniProtKB: I3MS46 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040138431   ⟸   XM_040282497
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040138432   ⟸   XM_040282498
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040138433   ⟸   XM_040282499
- Peptide Label: isoform X4
RefSeq Acc Id: ENSSTOP00000014941   ⟸   ENSSTOT00000028150
Protein Domains
Next to BRCA1 central


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000024680 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000028150.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
InterPro C6orf106_UBA-like UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  N_BRCA1_central UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/TrEMBL
NCBI Gene LOC101970985 ENTREZGENE
PANTHER OVARIAN CARCINOMA ANTIGEN CA125-RELATED UniProtKB/TrEMBL
  PROTEIN ILRUN UniProtKB/TrEMBL
Pfam N_BRCA1_IG UniProtKB/TrEMBL
  UBA_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF46934 UniProtKB/TrEMBL
UniProt I3MS46 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-26 Ilrun  inflammation and lipid regulator with UBA-like and NBR1-like domains  CUNH6orf106  chromosome unknown C6orf106 homolog  Symbol and/or name change 5135510 APPROVED
2017-07-13 CUNH6orf106  chromosome unknown C6orf106 homolog  LOC101970985  chromosome unknown open reading frame, human C6orf106  Symbol and/or name change 5135510 APPROVED