Pnrc2 (proline rich nuclear receptor coactivator 2) - Rat Genome Database

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Gene: Pnrc2 (proline rich nuclear receptor coactivator 2) Ictidomys tridecemlineatus
Analyze
Symbol: Pnrc2
Name: proline rich nuclear receptor coactivator 2
RGD ID: 12540223
Description: INVOLVED IN nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (inferred); ASSOCIATED WITH 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); Golgi apparatus (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: proline-rich nuclear receptor coactivator 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505843,236,376 - 43,240,413 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364749,061,691 - 9,065,195 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364749,061,672 - 9,065,195 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
Golgi apparatus  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)
P-body  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Pnrc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505843,236,376 - 43,240,413 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364749,061,691 - 9,065,195 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364749,061,672 - 9,065,195 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PNRC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38123,959,164 - 23,963,462 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl123,956,839 - 23,963,462 (+)EnsemblGRCh38hg38GRCh38
GRCh37124,286,318 - 24,289,952 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,158,917 - 24,162,518 (+)NCBINCBI36Build 36hg18NCBI36
Build 34124,031,635 - 24,035,237NCBI
Celera122,617,006 - 22,620,657 (+)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef122,539,641 - 22,543,289 (+)NCBIHuRef
CHM1_1124,399,050 - 24,402,692 (+)NCBICHM1_1
T2T-CHM13v2.0123,797,250 - 23,800,884 (+)NCBIT2T-CHM13v2.0
Pnrc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394135,598,229 - 135,601,157 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4135,598,229 - 135,601,161 (-)EnsemblGRCm39 Ensembl
GRCm384135,870,917 - 135,873,846 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4135,870,918 - 135,873,850 (-)EnsemblGRCm38mm10GRCm38
MGSCv374135,426,841 - 135,429,761 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364135,143,005 - 135,145,903 (-)NCBIMGSCv36mm8
Celera4134,065,460 - 134,068,376 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map468.01NCBI
Pnrc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85153,387,522 - 153,390,506 (-)NCBIGRCr8
mRatBN7.25148,103,966 - 148,106,950 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5148,104,181 - 148,106,971 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl5148,095,699 - 148,107,242 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5150,803,083 - 150,806,068 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05152,577,340 - 152,580,319 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05152,559,361 - 152,562,346 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05154,220,552 - 154,223,536 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5154,218,852 - 154,223,536 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05157,985,390 - 157,988,374 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45154,652,576 - 154,655,560 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5146,512,033 - 146,515,017 (-)NCBICelera
Cytogenetic Map5q36NCBI
Pnrc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554523,826,337 - 3,829,896 (+)NCBIChiLan1.0ChiLan1.0
PNRC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21202,965,630 - 202,977,716 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11202,068,675 - 202,081,350 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0123,155,018 - 23,167,105 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1124,135,973 - 24,148,082 (+)NCBIpanpan1.1PanPan1.1panPan2
PNRC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,602,514 - 75,606,420 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha272,173,539 - 72,177,474 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0276,162,581 - 76,166,507 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1272,984,746 - 72,988,671 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0273,991,592 - 73,995,523 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0274,996,971 - 75,000,896 (-)NCBIUU_Cfam_GSD_1.0
PNRC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl681,722,026 - 81,726,489 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1681,722,926 - 81,726,492 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PNRC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120108,730,228 - 108,733,837 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20108,731,791 - 108,732,207 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660337,620,230 - 7,623,867 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pnrc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247648,455,556 - 8,459,371 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247648,455,340 - 8,459,371 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000000948   ⟹   ENSSTOP00000017006
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364749,061,691 - 9,065,195 (+)Ensembl
RefSeq Acc Id: XM_005317599   ⟹   XP_005317656
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505843,236,894 - 43,240,413 (+)NCBI
SpeTri2.0NW_0049364749,061,672 - 9,065,195 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040288109   ⟹   XP_040144043
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505843,236,376 - 43,237,965 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005317656 (Get FASTA)   NCBI Sequence Viewer  
  XP_040144043 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000017006.1
GenBank Protein KAG3282407 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005317656   ⟸   XM_005317599
- Peptide Label: isoform X2
- UniProtKB: I3MY11 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040144043   ⟸   XM_040288109
- Peptide Label: isoform X1
RefSeq Acc Id: ENSSTOP00000017006   ⟸   ENSSTOT00000000948


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000953 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000948.3 UniProtKB/TrEMBL
InterPro PNRC1/2 UniProtKB/TrEMBL
NCBI Gene Pnrc2 ENTREZGENE
PANTHER PTHR15405 UniProtKB/TrEMBL
  PTHR15405:SF6 UniProtKB/TrEMBL
Pfam PNRC UniProtKB/TrEMBL
UniProt I3MY11 ENTREZGENE, UniProtKB/TrEMBL