Lamb4 (laminin subunit beta 4) - Rat Genome Database

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Gene: Lamb4 (laminin subunit beta 4) Ictidomys tridecemlineatus
Analyze
Symbol: Lamb4
Name: laminin subunit beta 4
RGD ID: 12539088
Description: INVOLVED IN animal organ morphogenesis (inferred); substrate adhesion-dependent cell spreading (inferred); tissue development (inferred); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN basement membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: laminin subunit beta-4
RGD Orthologs
Human
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511854,925,252 - 55,032,442 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647916,070,651 - 16,156,535 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647916,049,074 - 16,156,147 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Lamb4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511854,925,252 - 55,032,442 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647916,070,651 - 16,156,535 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647916,049,074 - 16,156,147 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LAMB4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387108,011,662 - 108,130,361 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7108,023,548 - 108,130,361 (-)EnsemblGRCh38hg38GRCh38
GRCh377107,663,998 - 107,770,806 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367107,451,232 - 107,558,037 (-)NCBINCBI36Build 36hg18NCBI36
Celera7102,470,963 - 102,577,805 (-)NCBICelera
Cytogenetic Map7q31.1NCBI
HuRef7102,026,492 - 102,133,100 (-)NCBIHuRef
CHM1_17107,597,688 - 107,704,521 (-)NCBICHM1_1
T2T-CHM13v2.07109,329,907 - 109,448,507 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27107,025,127 - 107,131,988 (-)NCBI
LAMB4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26144,869,783 - 144,976,288 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17193,139,752 - 193,246,258 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07100,005,662 - 100,112,128 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17112,727,343 - 112,825,707 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7112,727,343 - 112,825,707 (-)Ensemblpanpan1.1panPan2
LAMB4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11812,517,124 - 12,609,253 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1812,509,774 - 12,608,862 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1812,153,298 - 12,253,263 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01812,780,535 - 12,880,553 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1812,788,740 - 12,880,545 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11812,597,419 - 12,697,565 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01812,517,986 - 12,617,800 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01812,745,514 - 12,845,482 (+)NCBIUU_Cfam_GSD_1.0
LAMB4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9107,778,499 - 107,880,274 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19107,777,842 - 107,899,725 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29118,545,930 - 118,666,586 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LAMB4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12176,937,770 - 77,053,619 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2176,937,790 - 77,040,725 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604226,819,144 - 26,925,810 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lamb4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473921,655,896 - 21,754,368 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021722351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000030520   ⟹   ENSSTOP00000025803
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647916,070,651 - 16,156,535 (+)Ensembl
RefSeq Acc Id: XM_021722351   ⟹   XP_021578026
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511854,925,252 - 55,032,442 (+)NCBI
SpeTri2.0NW_00493647916,049,074 - 16,156,147 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021578026 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000025803.1
GenBank Protein KAG3277786 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021578026   ⟸   XM_021722351
- UniProtKB: A0A287CX02 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000025803   ⟸   ENSSTOT00000030520
Protein Domains
Laminin EGF-like   Laminin IV type B


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000031581 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000030520.1 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/TrEMBL
  Tie2 ligand-binding domain superfamily UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_IV_B UniProtKB/TrEMBL
NCBI Gene Lamb4 ENTREZGENE
PANTHER LAMININ SUBUNIT GAMMA-1 UniProtKB/TrEMBL
  NETRIN/LAMININ-RELATED UniProtKB/TrEMBL
Pfam Laminin_EGF UniProtKB/TrEMBL
  LAMININ_IV_B UniProtKB/TrEMBL
PRINTS EGFLAMININ UniProtKB/TrEMBL
PROSITE EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  LAMININ_IVB UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
UniProt A0A287CX02 ENTREZGENE, UniProtKB/TrEMBL