Agxt2 (alanine--glyoxylate aminotransferase 2) - Rat Genome Database

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Gene: Agxt2 (alanine--glyoxylate aminotransferase 2) Ictidomys tridecemlineatus
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Symbol: Agxt2
Name: alanine--glyoxylate aminotransferase 2
RGD ID: 12537212
Description: ENCODES a protein that exhibits beta-alanine-pyruvate transaminase activity (ortholog); INVOLVED IN glycine biosynthetic process, by transamination of glyoxylate (inferred); glyoxylate catabolic process (inferred); L-alanine catabolic process, by transamination (inferred); ASSOCIATED WITH alpha-methylacyl-CoA racemase deficiency (ortholog); Beta-Aminoisobutyric Acid, Urinary Excretion of (ortholog); inherited metabolic disorder (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alanine--glyoxylate aminotransferase 2, mitochondrial; alanine--glyoxylate aminotransferase 2, transcript variant X1; alanine--glyoxylate aminotransferase 2, transcript variant X2; alanine--glyoxylate aminotransferase 2, transcript variant X3; alanine--glyoxylate aminotransferase 2, transcript variant X4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213224,827,079 - 224,863,177 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365186,508,928 - 6,544,146 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365186,508,928 - 6,544,324 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
mitochondrion  (IEA,ISO)

Molecular Function

References

Genomics

Comparative Map Data
Agxt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213224,827,079 - 224,863,177 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365186,508,928 - 6,544,146 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365186,508,928 - 6,544,324 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGXT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38534,998,102 - 35,047,949 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl534,998,101 - 35,048,135 (-)EnsemblGRCh38hg38GRCh38
GRCh37534,998,207 - 35,048,054 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36535,033,963 - 35,083,756 (-)NCBINCBI36Build 36hg18NCBI36
Build 34535,033,962 - 35,083,756NCBI
Celera534,880,411 - 34,930,420 (-)NCBICelera
Cytogenetic Map5p13.2NCBI
HuRef534,946,958 - 34,996,974 (-)NCBIHuRef
CHM1_1535,000,510 - 35,050,560 (-)NCBICHM1_1
T2T-CHM13v2.0535,245,145 - 35,294,998 (-)NCBIT2T-CHM13v2.0
Agxt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391510,358,602 - 10,410,244 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1510,358,618 - 10,410,239 (+)EnsemblGRCm39 Ensembl
GRCm381510,358,516 - 10,410,158 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1510,358,532 - 10,410,153 (+)EnsemblGRCm38mm10GRCm38
MGSCv371510,288,334 - 10,339,493 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361510,303,304 - 10,354,463 (+)NCBIMGSCv36mm8
Celera1510,155,885 - 10,206,282 (+)NCBICelera
Cytogenetic Map15A1NCBI
Agxt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2259,336,252 - 59,377,664 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl259,336,283 - 59,377,926 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx266,436,973 - 66,485,549 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0264,558,502 - 64,607,076 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0259,559,851 - 59,608,437 (+)NCBIRnor_WKY
Rnor_6.0260,337,667 - 60,379,144 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl260,337,667 - 60,379,420 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0284,308,289 - 84,348,843 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4259,713,365 - 59,754,876 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1259,641,628 - 59,683,371 (+)NCBI
Celera259,294,201 - 59,335,576 (-)NCBICelera
Cytogenetic Map2q16NCBI
Agxt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542620,101,620 - 20,142,620 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542620,102,368 - 20,142,596 (-)NCBIChiLan1.0ChiLan1.0
AGXT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1580,601,554 - 80,652,575 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl580,601,554 - 80,652,575 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0575,322,351 - 75,373,261 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
AGXT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1473,292,117 - 73,327,769 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl473,292,101 - 73,327,962 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha472,908,514 - 72,944,184 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0473,797,662 - 73,833,439 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl473,797,685 - 73,833,434 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1473,545,393 - 73,581,098 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0473,668,622 - 73,704,659 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0474,202,253 - 74,237,942 (+)NCBIUU_Cfam_GSD_1.0
AGXT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1620,576,659 - 20,617,011 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11620,576,661 - 20,617,008 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21621,478,686 - 21,519,012 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGXT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1433,889,615 - 33,933,500 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl433,888,533 - 33,933,449 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607124,192,128 - 24,237,014 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Agxt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475919,858,148 - 19,938,229 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475919,858,255 - 19,909,516 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000008426   ⟹   ENSSTOP00000007552
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365186,514,918 - 6,544,146 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000030284   ⟹   ENSSTOP00000028050
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365186,508,928 - 6,544,146 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000033192   ⟹   ENSSTOP00000032139
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365186,514,617 - 6,544,146 (+)Ensembl
RefSeq Acc Id: XM_005325641   ⟹   XP_005325698
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213224,827,079 - 224,863,176 (-)NCBI
SpeTri2.0NW_0049365186,508,928 - 6,544,324 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021726607   ⟹   XP_021582282
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213224,827,079 - 224,863,177 (-)NCBI
SpeTri2.0NW_0049365186,508,928 - 6,544,324 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005325698 (Get FASTA)   NCBI Sequence Viewer  
  XP_021582282 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3266799 (Get FASTA)   NCBI Sequence Viewer  
  KAG3266800 (Get FASTA)   NCBI Sequence Viewer  
  KAG3266801 (Get FASTA)   NCBI Sequence Viewer  
  KAG3266802 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005325698   ⟸   XM_005325641
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021582282   ⟸   XM_021726607
- Peptide Label: isoform X1
- UniProtKB: A0A287D3F8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000007552   ⟸   ENSSTOT00000008426
RefSeq Acc Id: ENSSTOP00000032139   ⟸   ENSSTOT00000033192
RefSeq Acc Id: ENSSTOP00000028050   ⟸   ENSSTOT00000030284


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008427 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000007552.3 UniProtKB/TrEMBL
  ENSSTOP00000028050 ENTREZGENE
  ENSSTOP00000028050.1 UniProtKB/TrEMBL
  ENSSTOP00000032139 ENTREZGENE
  ENSSTOP00000032139.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008426.3 UniProtKB/TrEMBL
  ENSSTOT00000030284.1 UniProtKB/TrEMBL
  ENSSTOT00000033192.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/TrEMBL
InterPro Aminotrans_3 UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_small UniProtKB/TrEMBL
NCBI Gene Agxt2 ENTREZGENE
Pfam Aminotran_3 UniProtKB/TrEMBL
PIRSF Transaminase_4ab_Lys_Orn UniProtKB/TrEMBL
PROSITE AA_TRANSFER_CLASS_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF53383 UniProtKB/TrEMBL
UniProt A0A287D3F8 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DF17_ICTTR UniProtKB/TrEMBL
  I3MBL7_ICTTR UniProtKB/TrEMBL