Heatr5a (HEAT repeat containing 5A) - Rat Genome Database

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Gene: Heatr5a (HEAT repeat containing 5A) Ictidomys tridecemlineatus
Analyze
Symbol: Heatr5a
Name: HEAT repeat containing 5A
RGD ID: 12534210
Description: INVOLVED IN endocytosis (inferred); protein localization (inferred); retrograde transport, endosome to Golgi (inferred); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); genetic disease (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN endocytic vesicle (inferred); Golgi apparatus (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: HEAT repeat containing 5A, transcript variant X1; HEAT repeat containing 5A, transcript variant X2; HEAT repeat containing 5A, transcript variant X3; HEAT repeat containing 5A, transcript variant X4; HEAT repeat containing 5A, transcript variant X5; HEAT repeat containing 5A, transcript variant X6; HEAT repeat containing 5A, transcript variant X7; HEAT repeat-containing protein 5A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864042,396,649 - 42,518,372 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364945,903,892 - 6,008,582 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364945,902,543 - 6,024,106 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Heatr5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864042,396,649 - 42,518,372 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364945,903,892 - 6,008,582 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364945,902,543 - 6,024,106 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HEATR5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381431,291,788 - 31,420,550 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1431,291,788 - 31,420,550 (-)EnsemblGRCh38hg38GRCh38
GRCh371431,760,994 - 31,889,756 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361430,832,103 - 30,927,932 (-)NCBINCBI36Build 36hg18NCBI36
Build 341430,831,558 - 30,922,706NCBI
Celera1411,626,496 - 11,723,479 (-)NCBICelera
Cytogenetic Map14q12NCBI
HuRef1411,878,270 - 12,007,294 (-)NCBIHuRef
CHM1_11431,760,051 - 31,888,641 (-)NCBICHM1_1
T2T-CHM13v2.01425,489,675 - 25,618,192 (-)NCBIT2T-CHM13v2.0
Heatr5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391251,922,654 - 52,018,154 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1251,922,654 - 52,018,104 (-)EnsemblGRCm39 Ensembl
GRCm381251,875,871 - 51,971,371 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1251,875,871 - 51,971,321 (-)EnsemblGRCm38mm10GRCm38
MGSCv371252,976,860 - 53,072,308 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361252,797,493 - 52,892,941 (-)NCBIMGSCv36mm8
Celera1253,180,906 - 53,275,990 (-)NCBICelera
Cytogenetic Map12C1NCBI
Heatr5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8675,057,226 - 75,155,207 (-)NCBIGRCr8
mRatBN7.2669,321,869 - 69,419,861 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl669,321,869 - 69,419,773 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0672,648,654 - 72,750,202 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,648,662 - 72,750,170 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0682,211,311 - 82,299,984 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4672,024,109 - 72,112,681 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera668,197,744 - 68,295,557 (-)NCBICelera
Cytogenetic Map6q23NCBI
Heatr5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540929,208,050 - 29,312,752 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540929,208,050 - 29,312,752 (+)NCBIChiLan1.0ChiLan1.0
HEATR5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21532,622,546 - 32,751,728 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11431,839,050 - 31,968,233 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01412,070,011 - 12,230,065 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11430,267,861 - 30,395,893 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1430,267,861 - 30,395,893 (-)Ensemblpanpan1.1panPan2
HEATR5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1810,561,723 - 10,673,506 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl810,562,425 - 10,658,597 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha810,488,485 - 10,522,654 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0810,663,584 - 10,775,409 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl810,663,658 - 10,775,356 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1810,346,098 - 10,457,867 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0810,423,220 - 10,534,811 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0810,707,243 - 10,819,049 (-)NCBIUU_Cfam_GSD_1.0
HEATR5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl768,211,624 - 68,259,794 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1768,143,597 - 68,259,087 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2773,024,717 - 73,140,661 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Heatr5a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624820907,396 - 1,021,455 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624820891,562 - 1,022,586 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005322660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005322661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021724685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021724686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021724687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021724688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021724689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040275219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002483665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005729345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000004652   ⟹   ENSSTOP00000004174
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364945,903,892 - 6,008,582 (-)Ensembl
RefSeq Acc Id: XM_021724685   ⟹   XP_021580360
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864042,396,649 - 42,518,181 (-)NCBI
SpeTri2.0NW_0049364945,902,543 - 6,024,106 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040275212   ⟹   XP_040131146
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864042,396,649 - 42,518,371 (-)NCBI
RefSeq Acc Id: XM_040275213   ⟹   XP_040131147
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864042,396,649 - 42,518,371 (-)NCBI
RefSeq Acc Id: XM_040275214   ⟹   XP_040131148
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864042,396,649 - 42,518,371 (-)NCBI
RefSeq Acc Id: XM_040275215   ⟹   XP_040131149
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864042,396,649 - 42,518,371 (-)NCBI
RefSeq Acc Id: XM_040275216   ⟹   XP_040131150
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864042,396,649 - 42,518,371 (-)NCBI
RefSeq Acc Id: XM_040275217   ⟹   XP_040131151
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864042,396,649 - 42,518,371 (-)NCBI
RefSeq Acc Id: XM_040275218   ⟹   XP_040131152
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864042,396,649 - 42,518,372 (-)NCBI
RefSeq Acc Id: XM_040275219   ⟹   XP_040131153
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864042,396,649 - 42,478,956 (-)NCBI
RefSeq Acc Id: XR_005729345
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864042,398,709 - 42,518,372 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021580360   ⟸   XM_021724685
- Peptide Label: isoform X1
- UniProtKB: I3M4M6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040131152   ⟸   XM_040275218
- Peptide Label: isoform X7
- UniProtKB: I3M4M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131149   ⟸   XM_040275215
- Peptide Label: isoform X4
- UniProtKB: I3M4M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131147   ⟸   XM_040275213
- Peptide Label: isoform X2
- UniProtKB: I3M4M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131151   ⟸   XM_040275217
- Peptide Label: isoform X6
- UniProtKB: I3M4M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131150   ⟸   XM_040275216
- Peptide Label: isoform X5
- UniProtKB: I3M4M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131148   ⟸   XM_040275214
- Peptide Label: isoform X3
- UniProtKB: I3M4M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131146   ⟸   XM_040275212
- Peptide Label: isoform X1
- UniProtKB: I3M4M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040131153   ⟸   XM_040275219
- Peptide Label: isoform X8
- UniProtKB: I3M4M6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000004174   ⟸   ENSSTOT00000004652


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004620 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004652.3 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Laa1/Sip1/HEATR5 UniProtKB/TrEMBL
  Laa1/Sip1/HEATR5-like_HEAT UniProtKB/TrEMBL
NCBI Gene Heatr5a ENTREZGENE
PANTHER HEAT REPEAT-CONTAINING PROTEIN 5A UniProtKB/TrEMBL
  PTHR21663 UniProtKB/TrEMBL
Pfam Laa1_Sip1_HTR5 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt I3M4M6 ENTREZGENE, UniProtKB/TrEMBL