Plcd1 (phospholipase C delta 1) - Rat Genome Database
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Gene: Plcd1 (phospholipase C delta 1) Ictidomys tridecemlineatus
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Symbol: Plcd1
Name: phospholipase C delta 1
RGD ID: 12530528
Description: ENCODES a protein that exhibits calcium ion binding (ortholog); calcium-dependent phospholipid binding (ortholog); GTPase activating protein binding (ortholog); INVOLVED IN angiogenesis (ortholog); G protein-coupled receptor signaling pathway (ortholog); labyrinthine layer blood vessel development (ortholog); PARTICIPATES IN G protein mediated signaling pathway; ASSOCIATED WITH alopecia (ortholog); Alzheimer's disease (ortholog); Brugada syndrome (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
Orthologs:
Homo sapiens (human) : PLCD1 (phospholipase C delta 1)  HGNC  Alliance
Mus musculus (house mouse) : Plcd1 (phospholipase C, delta 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plcd1 (phospholipase C, delta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcd1 (phospholipase C delta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCD1 (phospholipase C delta 1)
Canis lupus familiaris (dog) : PLCD1 (phospholipase C delta 1)
Sus scrofa (pig) : PLCD1 (phospholipase C delta 1)
Chlorocebus sabaeus (African green monkey) : PLCD1 (phospholipase C delta 1)
Heterocephalus glaber (naked mole-rat) : Plcd1 (phospholipase C delta 1)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647327,364,404 - 27,387,337 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Plcd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647327,364,404 - 27,387,337 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl338,007,496 - 38,029,762 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl338,007,496 - 38,029,642 (-)EnsemblGRCh38hg38GRCh38
GRCh38338,007,496 - 38,029,642 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37338,048,987 - 38,071,154 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36338,023,991 - 38,059,068 (-)NCBINCBI36hg18NCBI36
Build 34338,024,010 - 38,046,119NCBI
Celera337,983,370 - 38,005,535 (-)NCBI
Cytogenetic Map3p22.2NCBI
HuRef337,991,684 - 38,013,851 (-)NCBIHuRef
CHM1_1338,000,639 - 38,022,806 (-)NCBICHM1_1
Plcd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399118,900,595 - 118,922,570 (-)NCBI
GRCm389119,071,527 - 119,093,502 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9119,071,527 - 119,093,502 (-)EnsemblGRCm38mm10GRCm38
MGSCv379118,980,645 - 119,002,614 (-)NCBIGRCm37mm9NCBIm37
MGSCv369118,920,225 - 118,942,194 (-)NCBImm8
Celera9119,539,423 - 119,561,381 (-)NCBICelera
Cytogenetic Map9F3NCBI
Plcd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08127,753,514 - 127,782,070 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8127,753,539 - 127,782,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08126,970,643 - 126,991,422 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,023,090 - 124,052,193 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18124,042,827 - 124,071,930 (-)NCBI
Celera8117,968,204 - 117,991,136 (-)NCBICelera
Cytogenetic Map8q32NCBI
Plcd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554214,856,366 - 4,880,309 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554214,856,366 - 4,880,309 (-)NCBIChiLan1.0ChiLan1.0
PLCD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1338,189,496 - 38,211,784 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl338,189,496 - 38,206,886 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0337,906,359 - 37,928,564 (-)NCBIMhudiblu_PPA_v0panPan3
PLCD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl237,781,787 - 7,805,336 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1237,782,495 - 7,804,969 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
PLCD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1322,851,584 - 22,865,175 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11322,851,581 - 22,872,950 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21324,826,459 - 24,847,853 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCD1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl151,373,234 - 1,395,711 (+)Ensembl
ChlSab1.1151,372,874 - 1,395,475 (+)NCBI
Plcd1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477320,108,383 - 20,130,630 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005317364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGTP01006783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005317364   ⟹   XP_005317421
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_00493647327,364,404 - 27,387,337 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005317421 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005317421   ⟸   XM_005317364
- UniProtKB: I3LYR8 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
C2   EF-hand   PH   PI-PLC Y-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000001537 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000001375 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000001536 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  PH_dom-like UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/TrEMBL
  PLC-delta1 UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  PLC_EF-hand-like UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/TrEMBL
NCBI Gene Plcd1 ENTREZGENE
PANTHER PTHR10336 UniProtKB/TrEMBL
  PTHR10336:SF80 UniProtKB/TrEMBL
Pfam EF-hand_like UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PH_12 UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/TrEMBL
PRINTS PHPHLIPASEC UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
  PLCXc UniProtKB/TrEMBL
  PLCYc UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
  SSF51695 UniProtKB/TrEMBL
UniProt I3LYR8 ENTREZGENE, UniProtKB/TrEMBL