Slc17a7 (solute carrier family 17 member 7) - Rat Genome Database

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Gene: Slc17a7 (solute carrier family 17 member 7) Ictidomys tridecemlineatus
Analyze
Symbol: Slc17a7
Name: solute carrier family 17 member 7
RGD ID: 12530186
Description: ENCODES a protein that exhibits chloride channel activity (ortholog); extracellularly glutamate-gated chloride channel activity (ortholog); L-glutamate uniporter activity (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); chloride transport (ortholog); establishment of localization in cell (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 12 (ortholog); genetic disease (ortholog); learning disability (ortholog); FOUND IN cerebellar mossy fiber (ortholog); excitatory synapse (ortholog); presynaptic active zone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: vesicular glutamate transporter 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,689,372 - 21,700,795 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,306,931 - 3,318,279 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,307,562 - 3,318,184 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slc17a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,689,372 - 21,700,795 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,306,931 - 3,318,279 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,307,562 - 3,318,184 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC17A7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,429,401 - 49,441,527 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,429,401 - 49,442,360 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,932,658 - 49,944,784 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,624,470 - 54,636,596 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,624,469 - 54,636,596NCBI
Celera1946,800,275 - 46,812,426 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,309,356 - 46,321,531 (-)NCBIHuRef
CHM1_11949,934,593 - 49,946,744 (-)NCBICHM1_1
T2T-CHM13v2.01952,426,980 - 52,439,104 (-)NCBIT2T-CHM13v2.0
Slc17a7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,813,345 - 44,825,563 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,813,373 - 44,825,566 (+)EnsemblGRCm39 Ensembl
GRCm38745,163,921 - 45,176,139 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,163,949 - 45,176,142 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,419,291 - 52,431,509 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,037,600 - 45,044,181 (+)NCBIMGSCv36mm8
Celera740,619,812 - 40,632,032 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.16NCBI
Slc17a7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,786,172 - 104,798,049 (+)NCBIGRCr8
mRatBN7.2195,649,709 - 95,661,591 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,649,745 - 95,661,588 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,035,136 - 101,046,992 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,507,805 - 109,519,655 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,798,210 - 102,810,056 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,161,265 - 101,172,292 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,161,252 - 101,173,174 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,226,212 - 102,237,165 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,640,743 - 95,651,938 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,718,860 - 95,730,049 (+)NCBI
Celera189,908,033 - 89,919,082 (+)NCBICelera
Cytogenetic Map1q22NCBI
Slc17a7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,399,182 - 1,409,134 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,399,182 - 1,409,074 (+)NCBIChiLan1.0ChiLan1.0
SLC17A7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,546,137 - 55,558,265 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,466,481 - 57,478,608 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,443,076 - 46,455,195 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,365,811 - 55,377,438 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,365,811 - 55,377,438 (-)Ensemblpanpan1.1panPan2
SLC17A7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,054,242 - 107,064,444 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,054,410 - 107,063,550 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,637,561 - 106,647,714 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,574,355 - 107,584,513 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,574,336 - 107,584,513 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,247,363 - 107,257,512 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,889,697 - 106,900,075 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,730,574 - 107,740,729 (+)NCBIUU_Cfam_GSD_1.0
SLC17A7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,511,124 - 54,521,611 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,511,121 - 54,521,616 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,240,102 - 50,250,578 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC17A7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,609,766 - 42,622,004 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,609,706 - 42,621,925 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,537,441 - 22,549,736 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc17a7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248324,765,212 - 4,775,515 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,765,233 - 4,775,515 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000014609   ⟹   ENSSTOP00000013087
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366643,306,931 - 3,318,279 (-)Ensembl
RefSeq Acc Id: XM_005336671   ⟹   XP_005336728
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934921,689,372 - 21,699,976 (-)NCBI
SpeTri2.0NW_0049366643,307,562 - 3,318,184 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040279327   ⟹   XP_040135261
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934921,689,372 - 21,700,795 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005336728 (Get FASTA)   NCBI Sequence Viewer  
  XP_040135261 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000013087.2
GenBank Protein KAG3256501 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005336728   ⟸   XM_005336671
- Peptide Label: isoform X1
- UniProtKB: I3MN88 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040135261   ⟸   XM_040279327
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000013087   ⟸   ENSSTOT00000014609
Protein Domains
Major facilitator superfamily (MFS) profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014610 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014609.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/TrEMBL
InterPro MFS UniProtKB/TrEMBL
  MFS_dom UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
NCBI Gene Slc17a7 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 17 UniProtKB/TrEMBL
  VESICULAR GLUTAMATE TRANSPORTER 1 UniProtKB/TrEMBL
Pfam MFS_1 UniProtKB/TrEMBL
PROSITE MFS UniProtKB/TrEMBL
Superfamily-SCOP SSF103473 UniProtKB/TrEMBL
UniProt I3MN88 ENTREZGENE, UniProtKB/TrEMBL