Lonrf2 (LON peptidase N-terminal domain and ring finger 2) - Rat Genome Database

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Gene: Lonrf2 (LON peptidase N-terminal domain and ring finger 2) Ictidomys tridecemlineatus
Analyze
Symbol: Lonrf2
Name: LON peptidase N-terminal domain and ring finger 2
RGD ID: 12527040
Description: ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LON peptidase N-terminal domain and RING finger protein 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629285,944,309 - 85,984,539 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936661584,942 - 622,823 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936661584,948 - 623,507 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Lonrf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629285,944,309 - 85,984,539 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936661584,942 - 622,823 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936661584,948 - 623,507 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LONRF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382100,271,875 - 100,322,501 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2100,271,875 - 100,322,501 (-)EnsemblGRCh38hg38GRCh38
GRCh372100,888,337 - 100,938,963 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362100,256,185 - 100,305,627 (-)NCBINCBI36Build 36hg18NCBI36
Celera295,094,286 - 95,143,712 (-)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef294,654,510 - 94,703,915 (-)NCBIHuRef
CHM1_12100,894,158 - 100,943,545 (-)NCBICHM1_1
T2T-CHM13v2.02100,730,785 - 100,781,377 (-)NCBIT2T-CHM13v2.0
Lonrf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39138,832,750 - 38,875,768 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl138,832,726 - 38,875,792 (-)EnsemblGRCm39 Ensembl
GRCm38138,793,669 - 38,836,687 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl138,793,645 - 38,836,711 (-)EnsemblGRCm38mm10GRCm38
MGSCv37138,851,354 - 38,878,060 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36138,739,055 - 38,765,761 (-)NCBIMGSCv36mm8
Celera138,580,489 - 38,606,584 (-)NCBICelera
Cytogenetic Map1BNCBI
cM Map117.17NCBI
Lonrf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8948,524,962 - 48,566,353 (-)NCBIGRCr8
mRatBN7.2941,033,125 - 41,070,551 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl941,034,628 - 41,070,649 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0945,468,001 - 45,506,448 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl945,466,688 - 45,505,767 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0945,161,417 - 45,200,151 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4937,793,985 - 37,829,456 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera938,783,004 - 38,821,241 (-)NCBICelera
Cytogenetic Map9q22NCBI
LONRF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21227,903,086 - 27,952,756 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A27,905,854 - 27,955,517 (+)NCBINHGRI_mPanPan1
PanPan1.12A101,255,118 - 101,303,103 (-)NCBIpanpan1.1PanPan1.1panPan2
LONRF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11042,378,459 - 42,412,871 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1042,378,475 - 42,410,076 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1042,301,779 - 42,334,721 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01043,246,934 - 43,279,880 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1043,246,934 - 43,279,340 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11042,967,873 - 43,000,816 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01043,241,595 - 43,274,524 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01043,431,190 - 43,464,138 (+)NCBIUU_Cfam_GSD_1.0
LONRF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl353,941,485 - 53,981,662 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1353,941,583 - 53,982,630 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2356,528,053 - 56,565,809 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LONRF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1144,014,773 - 4,055,193 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041171,630,965 - 171,672,349 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005336383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010001352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000012205   ⟹   ENSSTOP00000010941
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936661584,942 - 622,823 (+)Ensembl
RefSeq Acc Id: XM_005336383   ⟹   XP_005336440
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629285,944,309 - 85,984,539 (-)NCBI
SpeTri2.0NW_004936661584,948 - 623,507 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005336440 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000010941.2
GenBank Protein KAG3268124 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005336440   ⟸   XM_005336383
- UniProtKB: I3MIR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000010941   ⟸   ENSSTOT00000012205
Protein Domains
Lon N-terminal   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000012203 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000012205.3 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  2.30.130.40 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro Lon_prtase_N_sf UniProtKB/TrEMBL
  Lon_substr-bd UniProtKB/TrEMBL
  PUA-like_sf UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
NCBI Gene Lonrf2 ENTREZGENE
PANTHER LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 2 UniProtKB/TrEMBL
  RING FINGER PROTEIN 127 UniProtKB/TrEMBL
Pfam LON_substr_bdg UniProtKB/TrEMBL
  zf-C3HC4_2 UniProtKB/TrEMBL
PROSITE LON_N UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART LON UniProtKB/TrEMBL
  RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
  SSF88697 UniProtKB/TrEMBL
UniProt I3MIR0 ENTREZGENE, UniProtKB/TrEMBL