Nr1d1 (nuclear receptor subfamily 1 group D member 1) - Rat Genome Database

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Gene: Nr1d1 (nuclear receptor subfamily 1 group D member 1) Ictidomys tridecemlineatus
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Symbol: Nr1d1
Name: nuclear receptor subfamily 1 group D member 1
RGD ID: 12526993
Description: ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular glucose homeostasis (ortholog); cellular response to interleukin-1 (ortholog); cellular response to lipopolysaccharide (ortholog); ASSOCIATED WITH alcoholic liver cirrhosis (ortholog); Cerebral Small Vessel Diseases (ortholog); Chemical and Drug Induced Liver Injury (ortholog); FOUND IN chromatin (ortholog); cytoplasm (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560221,861,286 - 21,868,939 (+)NCBI
SpeTri2.0NW_00493649015,206,194 - 15,213,858 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular glucose homeostasis  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to tumor necrosis factor  (ISO)
cholesterol homeostasis  (ISO)
circadian regulation of gene expression  (ISO)
circadian rhythm  (ISO)
circadian temperature homeostasis  (ISO)
glycogen biosynthetic process  (ISO)
negative regulation of astrocyte activation  (ISO)
negative regulation of cold-induced thermogenesis  (ISO)
negative regulation of I-kappaB kinase/NF-kappaB signaling  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of microglial cell activation  (ISO)
negative regulation of neuroinflammatory response  (ISO)
negative regulation of toll-like receptor 4 signaling pathway  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
photoperiodism  (ISO)
positive regulation of bile acid biosynthetic process  (ISO)
positive regulation of circadian rhythm  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
proteasomal protein catabolic process  (ISO)
protein destabilization  (ISO)
regulation of circadian rhythm  (ISO)
regulation of circadian sleep/wake cycle  (ISO)
regulation of fat cell differentiation  (ISO)
regulation of hepatic stellate cell activation  (ISO)
regulation of insulin secretion involved in cellular response to glucose stimulus  (ISO)
regulation of lipid metabolic process  (ISO)
regulation of transcription, DNA-templated  (ISO)
regulation of type B pancreatic cell proliferation  (ISO)
response to leptin  (ISO)

Cellular Component

References

Genomics

Comparative Map Data
Nr1d1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560221,861,286 - 21,868,939 (+)NCBI
SpeTri2.0NW_00493649015,206,194 - 15,213,858 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR1D1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1740,092,793 - 40,100,589 (-)EnsemblGRCh38hg38GRCh38
GRCh381740,092,793 - 40,100,589 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371738,249,046 - 38,256,842 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361735,502,567 - 35,510,499 (-)NCBINCBI36hg18NCBI36
Build 341735,502,566 - 35,510,499NCBI
Celera1734,909,147 - 34,917,084 (-)NCBI
Cytogenetic Map17q21.1NCBI
HuRef1734,042,773 - 34,050,715 (-)NCBIHuRef
CHM1_11738,484,740 - 38,492,682 (-)NCBICHM1_1
Nr1d1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391198,658,758 - 98,666,233 (-)NCBIGRCm39mm39
GRCm39 Ensembl1198,658,758 - 98,666,159 (-)Ensembl
GRCm381198,767,932 - 98,775,377 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1198,767,932 - 98,775,333 (-)EnsemblGRCm38mm10GRCm38
MGSCv371198,629,249 - 98,636,556 (-)NCBIGRCm37mm9NCBIm37
MGSCv361198,584,022 - 98,590,912 (-)NCBImm8
Celera11108,422,591 - 108,429,908 (-)NCBICelera
Cytogenetic Map11DNCBI
Nr1d1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21083,728,348 - 83,735,562 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1086,683,875 - 86,690,815 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01086,683,875 - 86,690,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01086,479,868 - 86,486,808 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41087,541,246 - 87,548,186 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11087,555,629 - 87,560,471 (-)NCBI
Celera1082,476,555 - 82,483,495 (-)NCBICelera
Cytogenetic Map10q31NCBI
Nr1d1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545114,742,735 - 14,750,999 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545114,743,763 - 14,750,903 (-)NCBIChiLan1.0ChiLan1.0
NR1D1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11717,409,669 - 17,417,600 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1717,409,669 - 17,417,600 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01717,188,390 - 17,196,315 (+)NCBIMhudiblu_PPA_v0panPan3
NR1D1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1922,461,556 - 22,469,243 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl922,461,705 - 22,469,053 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha921,933,902 - 21,941,575 (+)NCBI
ROS_Cfam_1.0923,254,745 - 23,262,432 (+)NCBI
UMICH_Zoey_3.1922,028,188 - 22,035,862 (+)NCBI
UNSW_CanFamBas_1.0922,287,169 - 22,294,857 (+)NCBI
UU_Cfam_GSD_1.0922,411,920 - 22,419,594 (+)NCBI
NR1D1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1222,263,657 - 22,271,643 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11222,263,549 - 22,274,131 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NR1D1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11666,078,990 - 66,086,927 (+)NCBI
ChlSab1.1 Ensembl1666,079,089 - 66,090,685 (+)Ensembl
Vero_WHO_p1.0NW_02366607736,982,347 - 36,990,288 (+)NCBI
Nr1d1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247953,102,424 - 3,109,497 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005321808   ⟹   XP_005321865
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560221,861,286 - 21,868,939 (+)NCBI
SpeTri2.0NW_00493649015,206,194 - 15,213,858 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040268814   ⟹   XP_040124748
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560221,865,004 - 21,868,939 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005321865 (Get FASTA)   NCBI Sequence Viewer  
  XP_040124748 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3269046 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005321865   ⟸   XM_005321808
- Peptide Label: isoform X1
- UniProtKB: I3M7Q0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040124748   ⟸   XM_040268814
- Peptide Label: isoform X2
Protein Domains
NR LBD   Nuclear receptor


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000006333 ENTREZGENE
Ensembl Protein ENSSTOP00000005658 ENTREZGENE
NCBI Gene Nr1d1 ENTREZGENE
UniProt I3M7Q0 ENTREZGENE