Ptpn23 (protein tyrosine phosphatase non-receptor type 23) - Rat Genome Database
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Gene: Ptpn23 (protein tyrosine phosphatase non-receptor type 23) Ictidomys tridecemlineatus
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Symbol: Ptpn23
Name: protein tyrosine phosphatase non-receptor type 23
RGD ID: 12526209
Description: ENCODES a protein that exhibits protein kinase binding (ortholog); protein tyrosine phosphatase activity (ortholog); INVOLVED IN cilium assembly (ortholog); early endosome to late endosome transport (ortholog); endocytic recycling (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); NEURODEVELOPMENTAL DISORDER AND STRUCTURAL BRAIN ANOMALIES WITH OR WITHOUT SEIZURES AND SPASTICITY (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN ciliary basal body (ortholog); cytoplasm (ortholog); early endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: tyrosine-protein phosphatase non-receptor type 23
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365961,094,285 - 1,124,483 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
Ptpn23
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365961,094,285 - 1,124,483 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPN23
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl347,381,011 - 47,413,435 (+)EnsemblGRCh38hg38GRCh38
GRCh38347,381,001 - 47,413,435 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37347,422,511 - 47,454,925 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh37347,422,383 - 47,454,931 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36347,397,495 - 47,429,935 (+)NCBINCBI36hg18NCBI36
Build 34347,397,538 - 47,429,935NCBI
Celera347,361,133 - 47,393,570 (+)NCBI
Cytogenetic Map3p21.31NCBI
HuRef347,465,405 - 47,497,882 (+)NCBIHuRef
CHM1_1347,372,712 - 47,405,159 (+)NCBICHM1_1
Ptpn23
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,214,152 - 110,237,278 (-)NCBIGRCm39mm39
GRCm389110,385,084 - 110,408,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,385,082 - 110,408,213 (-)EnsemblGRCm38mm10GRCm38
MGSCv379110,287,593 - 110,310,714 (-)NCBIGRCm37mm9NCBIm37
MGSCv369110,230,249 - 110,253,380 (-)NCBImm8
Celera9110,114,048 - 110,137,187 (-)NCBICelera
Cytogenetic Map9F2NCBI
Ptpn23
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28110,360,804 - 110,383,271 (-)NCBI
Rnor_6.0 Ensembl8118,628,777 - 118,651,238 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08118,628,777 - 118,651,238 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08117,972,419 - 117,994,931 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,761,478 - 114,768,927 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18114,780,932 - 114,788,379 (-)NCBI
Celera8109,646,218 - 109,668,775 (-)NCBICelera
Cytogenetic Map8q32NCBI
Ptpn23
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542024,869,894 - 24,897,102 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542024,869,737 - 24,897,196 (-)NCBIChiLan1.0ChiLan1.0
PTPN23
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1348,378,367 - 48,413,739 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl348,379,810 - 48,413,488 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0347,280,706 - 47,314,268 (+)NCBIMhudiblu_PPA_v0panPan3
PTPN23
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2041,485,195 - 41,587,003 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12041,485,959 - 41,511,250 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
PTPN23
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1330,190,657 - 30,253,115 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11330,190,659 - 30,252,980 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21333,423,209 - 33,483,647 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTPN23
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,788,927 - 8,821,566 (+)NCBI
ChlSab1.1 Ensembl228,788,961 - 8,821,316 (+)Ensembl
Ptpn23
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473073,975,490 - 74,004,454 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005332933   ⟹   XP_005332990
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365961,094,285 - 1,124,483 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021731453   ⟹   XP_021587128
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365961,094,285 - 1,124,483 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005332990 (Get FASTA)   NCBI Sequence Viewer  
  XP_021587128 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005332990   ⟸   XM_005332933
- Peptide Label: isoform X1
- UniProtKB: I3MQN2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021587128   ⟸   XM_021731453
- Peptide Label: isoform X2
- Sequence:

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015955 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000014280 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015961 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.280 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro ALIX_V_dom UniProtKB/TrEMBL
  BRO1_dom UniProtKB/TrEMBL
  BRO1_sf UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTPase_domain UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  TYR_PHOSPHATASE_dom UniProtKB/TrEMBL
NCBI Gene Ptpn23 ENTREZGENE
Pfam ALIX_LYPXL_bnd UniProtKB/TrEMBL
  BRO1 UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE BRO1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART BRO1 UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
UniProt I3MQN2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 Ptpn23  protein tyrosine phosphatase non-receptor type 23    protein tyrosine phosphatase, non-receptor type 23  Symbol and/or name change 5135510 APPROVED