Kif5a (kinesin family member 5A) - Rat Genome Database

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Gene: Kif5a (kinesin family member 5A) Ictidomys tridecemlineatus
Analyze
Symbol: Kif5a
Name: kinesin family member 5A
RGD ID: 12525591
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); scaffold protein binding (ortholog); INVOLVED IN anterograde axonal protein transport (ortholog); cellular response to ethanol (ortholog); cellular response to nerve growth factor stimulus (ortholog); PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); amyotrophic lateral sclerosis type 25 (ortholog); FOUND IN apical dendrite (ortholog); axon (ortholog); central region of growth cone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kinesin family member 5A, transcript variant X1; kinesin family member 5A, transcript variant X2; kinesin heavy chain; kinesin heavy chain isoform 5A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,137,419 - 57,172,692 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,697,492 - 1,732,832 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,697,531 - 1,730,376 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kif5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,137,419 - 57,172,692 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,697,492 - 1,732,832 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,697,531 - 1,730,376 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KIF5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381257,550,044 - 57,586,633 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1257,546,026 - 57,586,633 (+)EnsemblGRCh38hg38GRCh38
GRCh371257,943,827 - 57,980,416 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361256,230,114 - 56,264,821 (+)NCBINCBI36Build 36hg18NCBI36
Build 341256,230,113 - 56,264,821NCBI
Celera1257,599,677 - 57,634,382 (+)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,981,745 - 55,016,257 (+)NCBIHuRef
CHM1_11257,911,685 - 57,946,386 (+)NCBICHM1_1
T2T-CHM13v2.01257,518,283 - 57,554,872 (+)NCBIT2T-CHM13v2.0
Kif5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,061,564 - 127,102,217 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,061,565 - 127,099,217 (-)EnsemblGRCm39 Ensembl
GRCm3810127,225,695 - 127,266,348 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,225,696 - 127,263,348 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710126,662,751 - 126,700,419 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610126,628,648 - 126,666,029 (-)NCBIMGSCv36mm8
Celera10129,618,645 - 129,655,868 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1074.5NCBI
Kif5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8764,937,210 - 64,974,339 (-)NCBIGRCr8
mRatBN7.2763,051,894 - 63,089,024 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,049,424 - 63,092,858 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx764,941,174 - 64,978,298 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,143,590 - 67,180,714 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0766,944,692 - 66,982,059 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0770,515,832 - 70,552,897 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,513,343 - 70,556,827 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0770,693,375 - 70,727,047 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,183,575 - 67,220,766 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,204,304 - 67,241,496 (-)NCBI
Celera760,193,348 - 60,229,555 (-)NCBICelera
Cytogenetic Map7q22NCBI
Kif5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554585,287,111 - 5,310,962 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554585,264,274 - 5,310,962 (+)NCBIChiLan1.0ChiLan1.0
KIF5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21036,754,420 - 36,791,175 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11236,751,196 - 36,787,946 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,340,201 - 31,376,849 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11231,599,376 - 31,635,677 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1231,599,376 - 31,635,327 (-)Ensemblpanpan1.1panPan2
KIF5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,637,007 - 1,666,790 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,636,932 - 1,664,767 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,700,232 - 1,729,959 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0101,646,391 - 1,676,129 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,646,235 - 1,676,121 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,624,071 - 1,653,916 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,865,983 - 1,895,693 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,990,984 - 2,020,928 (+)NCBIUU_Cfam_GSD_1.0
KIF5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,816,854 - 22,851,973 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,813,617 - 22,851,976 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KIF5A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11153,458,795 - 53,493,801 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037192,467,068 - 192,505,360 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kif5a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480210,375,774 - 10,409,566 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480210,375,132 - 10,409,575 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000001178   ⟹   ENSSTOP00000001053
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366461,697,967 - 1,729,187 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000034530   ⟹   ENSSTOP00000027064
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366461,697,492 - 1,732,832 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000038023   ⟹   ENSSTOP00000031334
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366461,697,492 - 1,732,832 (+)Ensembl
RefSeq Acc Id: XM_005335682   ⟹   XP_005335739
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,137,419 - 57,172,688 (-)NCBI
SpeTri2.0NW_0049366461,697,531 - 1,730,376 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040280418   ⟹   XP_040136352
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,137,419 - 57,172,692 (-)NCBI
RefSeq Acc Id: XM_040280419   ⟹   XP_040136353
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,137,419 - 57,172,691 (-)NCBI
RefSeq Acc Id: XM_040280420   ⟹   XP_040136354
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,137,419 - 57,172,691 (-)NCBI
RefSeq Acc Id: XM_040280421   ⟹   XP_040136355
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,137,419 - 57,172,690 (-)NCBI
RefSeq Acc Id: XM_040280422   ⟹   XP_040136356
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494557,137,419 - 57,172,690 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005335739   ⟸   XM_005335682
- Peptide Label: isoform X6
- UniProtKB: A0A287DCS6 (UniProtKB/TrEMBL),   I3LY42 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040136352   ⟸   XM_040280418
- Peptide Label: isoform X1
- UniProtKB: I3LY42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040136353   ⟸   XM_040280419
- Peptide Label: isoform X2
- UniProtKB: I3LY42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040136354   ⟸   XM_040280420
- Peptide Label: isoform X3
- UniProtKB: I3LY42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040136356   ⟸   XM_040280422
- Peptide Label: isoform X5
- UniProtKB: I3LY42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040136355   ⟸   XM_040280421
- Peptide Label: isoform X4
- UniProtKB: I3LY42 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000001053   ⟸   ENSSTOT00000001178
RefSeq Acc Id: ENSSTOP00000027064   ⟸   ENSSTOT00000034530
RefSeq Acc Id: ENSSTOP00000031334   ⟸   ENSSTOT00000038023
Protein Domains
Kinesin motor


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000001164 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000001178.3 UniProtKB/TrEMBL
  ENSSTOT00000034530.1 UniProtKB/TrEMBL
  ENSSTOT00000038023.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.850.10 UniProtKB/TrEMBL
  6.10.250.1590 UniProtKB/TrEMBL
InterPro Kinesin-like_fam UniProtKB/TrEMBL
  Kinesin_motor_CS UniProtKB/TrEMBL
  Kinesin_motor_dom UniProtKB/TrEMBL
  Kinesin_motor_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Kif5a ENTREZGENE
PANTHER CENTROMERE PROTEIN E UniProtKB/TrEMBL
  KINESIN MOTOR DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam Kinesin UniProtKB/TrEMBL
PRINTS KINESINHEAVY UniProtKB/TrEMBL
PROSITE KINESIN_MOTOR_1 UniProtKB/TrEMBL
  KINESIN_MOTOR_2 UniProtKB/TrEMBL
SMART KISc UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287D0K9_ICTTR UniProtKB/TrEMBL
  A0A287DCS6 ENTREZGENE, UniProtKB/TrEMBL
  I3LY42 ENTREZGENE, UniProtKB/TrEMBL