Ptgdr (prostaglandin D2 receptor)

Gene: Ptgdr (prostaglandin D2 receptor) Ictidomys tridecemlineatus

Analyze

Symbol:

Ptgdr

Name:

prostaglandin D2 receptor

RGD ID:

12524804

Description:

ENCODES a protein that exhibits prostaglandin D receptor activity (ortholog); INVOLVED IN adenosine metabolic process (ortholog); cellular response to prostaglandin D stimulus (ortholog); inflammatory response (ortholog); PARTICIPATES IN eicosanoid signaling pathway; prostaglandin D2 signaling pathway; ASSOCIATED WITH asthma (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	76,707,144 - 76,714,871 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936697	2,481,340 - 2,488,868 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936697	2,481,340 - 2,488,868 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (ISO)

COVID-19 (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenosine metabolic process (IEA,ISO)

cellular response to prostaglandin D stimulus (IEA,ISO)

G protein-coupled receptor signaling pathway (IEA)

inflammatory response (IEA,ISO)

male sex determination (IEA,ISO)

negative regulation of cytosolic calcium ion concentration (ISO)

positive regulation of cytosolic calcium ion concentration (IEA)

positive regulation of penile erection (ISO)

sleep (IEA,ISO)

vasodilation (ISO)

Cellular Component

membrane (IEA)

plasma membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IEA)

prostaglandin D receptor activity (IEA,ISO)

prostaglandin J receptor activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

eicosanoid signaling pathway (ISO)

prostaglandin D2 signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Ptgdr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	76,707,144 - 76,714,871 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936697	2,481,340 - 2,488,868 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936697	2,481,340 - 2,488,868 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PTGDR
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	52,267,698 - 52,280,914 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	52,267,698 - 52,276,724 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	52,734,416 - 52,743,442 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	51,804,181 - 51,813,192 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	51,804,180 - 51,813,191	NCBI
Celera	14	32,602,359 - 32,611,369 (+)	NCBI		Celera
Cytogenetic Map	14	q22.1	NCBI
HuRef	14	32,895,105 - 32,904,115 (+)	NCBI		HuRef
CHM1_1	14	52,673,595 - 52,682,607 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	46,474,808 - 46,488,025 (+)	NCBI		T2T-CHM13v2.0

Ptgdr
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	45,088,692 - 45,096,832 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	45,088,692 - 45,096,832 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	44,851,235 - 44,859,375 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	44,851,235 - 44,859,375 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	45,470,910 - 45,479,050 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	43,773,112 - 43,781,252 (-)	NCBI		MGSCv36	mm8
Celera	14	41,045,205 - 41,053,310 (-)	NCBI		Celera
Cytogenetic Map	14	C1	NCBI
cM Map	14	22.59	NCBI

Ptgdr
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	19,790,499 - 19,797,873 (+)	NCBI		GRCr8
mRatBN7.2	15	17,360,304 - 17,367,679 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	17,360,304 - 17,367,679 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	19,534,419 - 19,541,726 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	20,492,893 - 20,500,200 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	18,747,817 - 18,755,124 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	19,195,606 - 19,196,508 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	15	23,162,010 - 23,162,912 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	19,345,555 - 19,352,929 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	19,345,554 - 19,352,929 (+)	NCBI
Celera	15	17,315,866 - 17,323,221 (+)	NCBI		Celera
Cytogenetic Map	15	p14	NCBI

Ptgdr
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	10,801,328 - 10,810,066 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	10,801,370 - 10,810,161 (-)	NCBI	ChiLan1.0	ChiLan1.0

PTGDR
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	53,398,345 - 53,410,180 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	52,614,856 - 52,626,691 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	32,863,852 - 32,873,492 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	51,149,155 - 51,158,158 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	51,149,155 - 51,158,161 (+)	Ensembl	panpan1.1		panPan2

PTGDR
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	28,480,446 - 28,491,331 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	28,480,478 - 28,488,855 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	28,232,194 - 28,242,277 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	28,657,597 - 28,667,689 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	28,657,612 - 28,665,988 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	28,326,721 - 28,336,803 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	28,387,594 - 28,397,684 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	28,734,940 - 28,745,039 (+)	NCBI		UU_Cfam_GSD_1.0

PTGDR
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	181,955,339 - 181,966,178 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	181,953,506 - 182,006,375 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	202,227,952 - 202,279,018 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PTGDR
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	29,347,796 - 29,359,783 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	29,350,749 - 29,359,754 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	17,618,199 - 17,627,555 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ptgdr
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	16,777,678 - 16,785,130 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624731	16,776,050 - 16,785,178 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005337979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000025124 ⟹ ENSSTOP00000022190

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936697	2,481,340 - 2,488,868 (-)	Ensembl

RefSeq Acc Id:

XM_005337979 ⟹ XP_005338036

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	76,707,144 - 76,714,871 (-)	NCBI
SpeTri2.0	NW_004936697	2,481,340 - 2,488,868 (-)	NCBI

Sequence:

show sequence

ATGAAGTCTCCCTTCTATCCATGCCAGAACACCACCTCGGTGGAGAAAGGCAACTCAGCGACGA
TGGGCGGGGTACTGTTTAGTGCGGGCCTCCTGGGCAACCTGCTGGCCCTGGGGCTGCTGGCGCG
CTCAGGGCTAGGGTCTTGCCGACCGCGCCCGCGGCGCCCGCCGCCCTCGGTATTCTACGTGCTG
GTGTGCGGCCTGACCATCACCGACTTGCTGGGCAAGTGCCTGATAAGCCCGGTGGTTCTGGCTG
CCTATGCGCAAAATCGGAGCCTGCGGGGGCTAATGCCTGCGTCCGGCGACGAGTCGCTGTGCCA
AACCTTCGCTTTCTTCATGTCTTTCTTTGGGCTCGCATCGACGTTACAGCTCCTGGCCATGGCT
CTGGAGTGCTGGCTTTCCTTGGGGCACCCCTTCTTCTACCAAAGGCACATCACCCTACGCCGGG
GCGTACTCGTGGCTCCAGTGGTGGGTGCATTCTGCCTGGTTTTCTGCGCACTACCCTTGATGGG
TTTCGGGAAGTTCATTCAGTACTGCCCGGGCACCTGGTGCTTCATCCGGATGGTCCGCGATGAC
TCGATCTGGGTGGTGGTCTACTCCGTTCTCTACTCCACGCTCATGGCGCTGGTGGTTCTTGCCA
TCGTTCTGTGCAACCTGGGGGCGATGCGCAACCTTTACACTATGCACCAGCGACTGAGACGACA
CACGCGCTGTGGACTCAGGGACATCGCAGAGCCAGGCGCGGAGAAGAAGGTGGCATCCTCACAT
CCCTTGGAGGAACTGGATCACCTCCTGCTGCTGGCCCTCATGACCGTGCTCTTCACTATGTGCT
CTGTGCCTTTAATTTATCGTTCCTACTATGGAGCTGTCCAGGATGCCACTGAAGAATCGGACGA
TCTTCTAGCCTTGCGTTTCCTGTCTGTGATTTCAATTGTGGACCCATGGATTTTCATCATATTC
AGAACTTCAGTATTTCGAATGTTTTTCCACAAGATTTTCATAAGACCTCTTATGTATAGAAACT
GGCAGAGCCATTCCTATAAAACTAATGTGGAATCCAGTTTGTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005338036	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000022190.2
GenBank Protein	KAG3261433	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005338036 ⟸ XM_005337979

- UniProtKB:

I3NCU3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKSPFYPCQNTTSVEKGNSATMGGVLFSAGLLGNLLALGLLARSGLGSCRPRPRRPPPSVFYVL
VCGLTITDLLGKCLISPVVLAAYAQNRSLRGLMPASGDESLCQTFAFFMSFFGLASTLQLLAMA
LECWLSLGHPFFYQRHITLRRGVLVAPVVGAFCLVFCALPLMGFGKFIQYCPGTWCFIRMVRDD
SIWVVVYSVLYSTLMALVVLAIVLCNLGAMRNLYTMHQRLRRHTRCGLRDIAEPGAEKKVASSH
PLEELDHLLLLALMTVLFTMCSVPLIYRSYYGAVQDATEESDDLLALRFLSVISIVDPWIFIIF
RTSVFRMFFHKIFIRPLMYRNWQSHSYKTNVESSL

hide sequence

RefSeq Acc Id:

ENSSTOP00000022190 ⟸ ENSSTOT00000025124

Protein Domains

G-protein coupled receptors family 1 profile

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000024233	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000025124.2	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
	Pglndn_D_rcpt	UniProtKB/TrEMBL
	Prostanoid_rcpt	UniProtKB/TrEMBL
NCBI Gene	Ptgdr	ENTREZGENE
PANTHER	PTHR11866	UniProtKB/TrEMBL
	PTHR11866:SF14	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PRINTS	PROSTANOIDR	UniProtKB/TrEMBL
	PRSTNOIDDPR	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	I3NCU3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - SMPDB

Imported Annotations - PID (archival)