Ppp2r5a (protein phosphatase 2 regulatory subunit B'alpha) - Rat Genome Database

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Gene: Ppp2r5a (protein phosphatase 2 regulatory subunit B'alpha) Ictidomys tridecemlineatus
Analyze
Symbol: Ppp2r5a
Name: protein phosphatase 2 regulatory subunit B'alpha
RGD ID: 12523267
Description: ENCODES a protein that exhibits kinase binding (inferred); phosphoprotein phosphatase activity (inferred); protein phosphatase activator activity (inferred); INVOLVED IN negative regulation of protein localization to plasma membrane (inferred); positive regulation of protein dephosphorylation (inferred); signal transduction (inferred); PARTICIPATES IN Wnt signaling, canonical pathway; ASSOCIATED WITH Emphysema (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN centrosome (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934463,903,654 - 63,969,401 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365571,143,101 - 1,209,807 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365571,143,936 - 1,209,719 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ppp2r5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934463,903,654 - 63,969,401 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365571,143,101 - 1,209,807 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365571,143,936 - 1,209,719 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP2R5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381212,285,410 - 212,361,853 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1212,285,410 - 212,361,853 (+)EnsemblGRCh38hg38GRCh38
GRCh371212,458,752 - 212,535,195 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,525,502 - 210,601,828 (+)NCBINCBI36Build 36hg18NCBI36
Build 341208,847,273 - 208,923,599NCBI
Celera1185,685,982 - 185,760,829 (+)NCBICelera
Cytogenetic Map1q32.3NCBI
HuRef1183,135,716 - 183,210,570 (+)NCBIHuRef
CHM1_11213,731,558 - 213,808,070 (+)NCBICHM1_1
T2T-CHM13v2.01211,531,574 - 211,606,538 (+)NCBIT2T-CHM13v2.0
Ppp2r5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391191,084,178 - 191,129,238 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1191,084,172 - 191,135,469 (-)EnsemblGRCm39 Ensembl
GRCm381191,351,981 - 191,397,041 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1191,351,975 - 191,403,272 (-)EnsemblGRCm38mm10GRCm38
MGSCv371193,175,860 - 193,220,920 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361193,052,596 - 193,097,656 (-)NCBIMGSCv36mm8
Celera1198,282,109 - 198,324,528 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map196.28NCBI
Ppp2r5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813105,462,371 - 105,506,767 (-)NCBIGRCr8
mRatBN7.213102,931,264 - 102,975,661 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13102,931,264 - 102,975,661 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13105,451,304 - 105,495,698 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013106,835,157 - 106,879,551 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013104,050,237 - 104,094,632 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013110,033,550 - 110,077,946 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13110,033,550 - 110,077,946 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013114,599,131 - 114,643,527 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413107,413,761 - 107,458,156 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113107,602,873 - 107,647,661 (-)NCBI
Celera13102,370,409 - 102,414,549 (-)NCBICelera
Cytogenetic Map13q27NCBI
Ppp2r5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554065,059,826 - 5,115,312 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554065,059,826 - 5,115,312 (-)NCBIChiLan1.0ChiLan1.0
PPP2R5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2137,044,737 - 37,117,393 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1137,009,226 - 37,081,877 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01187,853,674 - 187,926,318 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11192,716,546 - 192,788,328 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1192,716,546 - 192,788,328 (+)Ensemblpanpan1.1panPan2
PPP2R5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1710,502,959 - 10,566,475 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl710,502,930 - 10,565,404 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha710,078,569 - 10,141,787 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0710,208,302 - 10,272,200 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl710,208,105 - 10,272,195 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1710,131,806 - 10,195,013 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0710,233,111 - 10,296,331 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0710,356,575 - 10,419,810 (+)NCBIUU_Cfam_GSD_1.0
PPP2R5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9131,003,903 - 131,076,338 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19131,003,903 - 131,075,803 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29144,051,576 - 144,124,384 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP2R5A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12517,163,429 - 17,237,519 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2517,162,544 - 17,237,524 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605517,663,928 - 17,738,158 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppp2r5a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477117,810,733 - 17,865,689 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005329433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010004404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSSTOT00000013572   ⟹   ENSSTOP00000012161
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365571,143,101 - 1,209,807 (-)Ensembl
RefSeq Acc Id: XM_005329433   ⟹   XP_005329490
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934463,903,654 - 63,969,401 (-)NCBI
SpeTri2.0NW_0049365571,143,936 - 1,209,719 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005329490 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000012161.3
GenBank Protein KAG3258137 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005329490   ⟸   XM_005329433
- UniProtKB: I3ML95 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000012161   ⟸   ENSSTOT00000013572


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013569 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013572.3 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  PP2A_B56 UniProtKB/TrEMBL
NCBI Gene Ppp2r5a ENTREZGENE
PANTHER PTHR10257 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT ALPHA ISOFORM UniProtKB/TrEMBL
Pfam B56 UniProtKB/TrEMBL
PIRSF PP2A_B56 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt I3ML95 ENTREZGENE, UniProtKB/TrEMBL