Cnnm4 (cyclin and CBS domain divalent metal cation transport mediator 4) - Rat Genome Database

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Gene: Cnnm4 (cyclin and CBS domain divalent metal cation transport mediator 4) Ictidomys tridecemlineatus
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Symbol: Cnnm4
Name: cyclin and CBS domain divalent metal cation transport mediator 4
RGD ID: 12521674
Description: ENCODES a protein that exhibits magnesium ion transmembrane transporter activity (inferred); sodium ion transmembrane transporter activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN enamel mineralization (ortholog); magnesium ion homeostasis (ortholog); magnesium ion transport (ortholog); ASSOCIATED WITH Amaurosis Hypertrichosis (ortholog); Cone Rod Dystrophy Amelogenesis Imperfecta (ortholog); fundus dystrophy (ortholog); FOUND IN dendrite (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cyclin and CBS domain divalent metal cation transport mediator 4, transcript variant X1; cyclin and CBS domain divalent metal cation transport mediator 4, transcript variant X2; cyclin M4; metal transporter CNNM4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629283,462,574 - 83,499,496 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936744714,721 - 771,835 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936744715,523 - 754,148 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Cnnm4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629283,462,574 - 83,499,496 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936744714,721 - 771,835 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936744715,523 - 754,148 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNNM4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38296,760,902 - 96,811,874 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl296,760,902 - 96,811,874 (+)EnsemblGRCh38hg38GRCh38
GRCh37297,426,639 - 97,477,611 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36296,790,366 - 96,841,355 (+)NCBINCBI36Build 36hg18NCBI36
Build 34296,848,753 - 96,899,482NCBI
Celera291,866,817 - 91,917,794 (+)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef291,387,237 - 91,438,072 (+)NCBIHuRef
CHM1_1297,431,549 - 97,482,554 (+)NCBICHM1_1
T2T-CHM13v2.0297,267,540 - 97,318,504 (+)NCBIT2T-CHM13v2.0
Cnnm4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39136,510,678 - 36,547,857 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl136,510,701 - 36,547,845 (+)EnsemblGRCm39 Ensembl
GRCm38136,471,597 - 36,508,776 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl136,471,620 - 36,508,764 (+)EnsemblGRCm38mm10GRCm38
MGSCv37136,528,442 - 36,565,621 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36136,416,531 - 36,451,508 (+)NCBIMGSCv36mm8
Celera136,258,387 - 36,295,587 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map115.28NCBI
Cnnm4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8946,207,602 - 46,246,817 (+)NCBIGRCr8
mRatBN7.2938,711,726 - 38,750,942 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl938,711,710 - 38,750,942 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx947,215,512 - 47,254,477 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0952,330,630 - 52,369,744 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0950,612,529 - 50,651,644 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0943,049,587 - 43,088,690 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl943,049,587 - 43,088,702 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0942,703,466 - 42,742,596 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4935,410,644 - 35,448,730 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1935,406,796 - 35,457,552 (+)NCBI
Celera936,478,287 - 36,517,394 (+)NCBICelera
Cytogenetic Map9q21NCBI
Cnnm4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554704,131,348 - 4,177,172 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554704,131,348 - 4,177,172 (+)NCBIChiLan1.0ChiLan1.0
CNNM4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21231,496,834 - 31,546,774 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A31,499,595 - 31,549,534 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A102,503,084 - 102,553,029 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A97,682,730 - 97,731,584 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A97,682,724 - 97,731,584 (+)Ensemblpanpan1.1panPan2
CNNM4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11045,157,418 - 45,197,323 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1045,138,538 - 45,197,244 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1045,083,622 - 45,123,394 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01046,033,014 - 46,072,636 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1046,034,439 - 46,072,842 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11045,744,456 - 45,783,944 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01046,030,983 - 46,070,598 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01046,214,541 - 46,254,352 (-)NCBIUU_Cfam_GSD_1.0
CNNM4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl356,814,832 - 56,858,453 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1356,814,823 - 56,858,460 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2359,514,271 - 59,548,974 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CNNM4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1141,095,514 - 1,137,937 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl141,095,719 - 1,135,572 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041168,525,282 - 168,574,499 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnnm4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247492,666,927 - 2,701,642 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247492,666,884 - 2,701,693 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000006552   ⟹   ENSSTOP00000005858
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936744714,721 - 752,042 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000022374   ⟹   ENSSTOP00000016024
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936744715,517 - 771,835 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000030422   ⟹   ENSSTOP00000026038
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936744715,517 - 771,835 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000034490   ⟹   ENSSTOP00000030549
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936744744,716 - 752,042 (+)Ensembl
RefSeq Acc Id: XM_005339592   ⟹   XP_005339649
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629283,462,580 - 83,499,496 (+)NCBI
SpeTri2.0NW_004936744715,523 - 754,148 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013364878   ⟹   XP_013220332
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629283,462,574 - 83,499,496 (+)NCBI
SpeTri2.0NW_004936744715,523 - 754,148 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040270759   ⟹   XP_040126693
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629283,462,580 - 83,499,068 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013220332   ⟸   XM_013364878
- Peptide Label: isoform X2
- UniProtKB: I3M850 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005339649   ⟸   XM_005339592
- Peptide Label: isoform X1
- UniProtKB: I3M850 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040126693   ⟸   XM_040270759
- Peptide Label: isoform X3
RefSeq Acc Id: ENSSTOP00000026038   ⟸   ENSSTOT00000030422
RefSeq Acc Id: ENSSTOP00000005858   ⟸   ENSSTOT00000006552
RefSeq Acc Id: ENSSTOP00000030549   ⟸   ENSSTOT00000034490
RefSeq Acc Id: ENSSTOP00000016024   ⟸   ENSSTOT00000022374
Protein Domains
CBS   CNNM transmembrane   Cyclic nucleotide-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000006555 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000006552.3 UniProtKB/TrEMBL
  ENSSTOT00000022374.2 UniProtKB/TrEMBL
  ENSSTOT00000030422.1 UniProtKB/TrEMBL
  ENSSTOT00000034490.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.10 UniProtKB/TrEMBL
  3.10.580.10 UniProtKB/TrEMBL
InterPro ACDP UniProtKB/TrEMBL
  CBS_dom UniProtKB/TrEMBL
  CBS_dom_sf UniProtKB/TrEMBL
  cNMP-bd-like UniProtKB/TrEMBL
  cNMP-bd_dom UniProtKB/TrEMBL
  CNNM UniProtKB/TrEMBL
  Ion_transp-like_CBS UniProtKB/TrEMBL
  RmlC-like_jellyroll UniProtKB/TrEMBL
NCBI Gene Cnnm4 ENTREZGENE
PANTHER METAL TRANSPORTER CNNM4 UniProtKB/TrEMBL
  PTHR12064 UniProtKB/TrEMBL
Pfam CBS UniProtKB/TrEMBL
  DUF21 UniProtKB/TrEMBL
PROSITE CBS UniProtKB/TrEMBL
  CNMP_BINDING_3 UniProtKB/TrEMBL
  CNNM UniProtKB/TrEMBL
Superfamily-SCOP SSF51206 UniProtKB/TrEMBL
  SSF54631 UniProtKB/TrEMBL
UniProt A0A287CXN3_ICTTR UniProtKB/TrEMBL
  A0A287DAJ0_ICTTR UniProtKB/TrEMBL
  I3M850 ENTREZGENE, UniProtKB/TrEMBL
  I3MV79_ICTTR UniProtKB/TrEMBL