Cnksr1 (connector enhancer of kinase suppressor of Ras 1) - Rat Genome Database

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Gene: Cnksr1 (connector enhancer of kinase suppressor of Ras 1) Ictidomys tridecemlineatus
Analyze
Symbol: Cnksr1
Name: connector enhancer of kinase suppressor of Ras 1
RGD ID: 12520798
Description: ENCODES a protein that exhibits protein-macromolecule adaptor activity (inferred); PARTICIPATES IN angiotensin II signaling pathway via AT2 receptor; interleukin-3 signaling pathway; ASSOCIATED WITH autosomal recessive hypercholesterolemia (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN cell cortex (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,872,995 - 44,882,216 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647410,699,819 - 10,706,591 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647410,697,777 - 10,706,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell cortex  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Cnksr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,872,995 - 44,882,216 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647410,699,819 - 10,706,591 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647410,697,777 - 10,706,988 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNKSR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,177,491 - 26,189,884 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,177,484 - 26,189,884 (+)EnsemblGRCh38hg38GRCh38
GRCh37126,503,982 - 26,516,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,376,590 - 26,388,962 (+)NCBINCBI36Build 36hg18NCBI36
Build 34126,188,144 - 26,200,515NCBI
Celera124,900,351 - 24,912,738 (+)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef124,758,021 - 24,770,408 (+)NCBIHuRef
CHM1_1126,617,199 - 26,629,585 (+)NCBICHM1_1
T2T-CHM13v2.0126,014,921 - 26,027,308 (+)NCBIT2T-CHM13v2.0
Cnksr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394133,955,352 - 133,965,737 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4133,955,352 - 133,965,710 (-)EnsemblGRCm39 Ensembl
GRCm384134,228,041 - 134,238,416 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,228,041 - 134,238,399 (-)EnsemblGRCm38mm10GRCm38
MGSCv374133,783,957 - 133,794,314 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364133,500,118 - 133,510,475 (-)NCBIMGSCv36mm8
MGSCv364131,800,745 - 131,810,306 (-)NCBIMGSCv36mm8
Celera4132,407,888 - 132,418,211 (-)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.5NCBI
Cnksr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85151,731,222 - 151,742,049 (-)NCBIGRCr8
mRatBN7.25146,447,495 - 146,458,332 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,447,497 - 146,458,212 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5149,149,245 - 149,159,880 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05150,919,634 - 150,930,291 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05150,905,459 - 150,916,094 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,447,348 - 152,458,005 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,446,845 - 152,458,023 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05156,206,363 - 156,217,020 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45152,972,551 - 152,983,208 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15152,982,589 - 152,993,370 (-)NCBI
Celera5144,865,185 - 144,875,842 (-)NCBICelera
Cytogenetic Map5q36NCBI
Cnksr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,624,306 - 5,634,923 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,624,334 - 5,634,861 (+)NCBIChiLan1.0ChiLan1.0
CNKSR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21200,681,749 - 200,700,402 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11199,779,866 - 199,798,352 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,438,092 - 25,450,953 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,505,376 - 26,517,561 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,505,513 - 26,517,225 (+)Ensemblpanpan1.1panPan2
CNKSR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,805,333 - 73,814,711 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,805,710 - 73,814,725 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,381,662 - 70,391,005 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,368,429 - 74,377,772 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,368,438 - 74,389,997 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1271,192,826 - 71,202,168 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0272,198,576 - 72,207,918 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0273,202,496 - 73,211,838 (-)NCBIUU_Cfam_GSD_1.0
CNKSR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,598,372 - 83,608,607 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,598,363 - 83,608,617 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2677,200,943 - 77,208,114 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CNKSR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120106,577,470 - 106,596,544 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20106,577,809 - 106,589,788 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660339,828,678 - 9,841,637 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnksr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476410,234,670 - 10,253,631 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476410,223,039 - 10,253,937 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000030080   ⟹   ENSSTOP00000020469
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647410,699,819 - 10,706,591 (+)Ensembl
RefSeq Acc Id: XM_040289162   ⟹   XP_040145096
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505844,872,995 - 44,882,216 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040145096 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000020469.2
GenBank Protein KAG3282474 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040145096   ⟸   XM_040289162
RefSeq Acc Id: ENSSTOP00000020469   ⟸   ENSSTOT00000030080
Protein Domains
CRIC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020206 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000030080.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
InterPro CRIC_domain UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
NCBI Gene Cnksr1 ENTREZGENE
PANTHER CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS UniProtKB/TrEMBL
  CONNECTOR ENHANCER OF KINASE SUPPRESSOR OF RAS 1 UniProtKB/TrEMBL
Pfam CRIC_ras_sig UniProtKB/TrEMBL
PROSITE CRIC UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47769 UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
UniProt I3N7X3_ICTTR UniProtKB/TrEMBL