Dip2a (disco interacting protein 2 homolog A) - Rat Genome Database

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Gene: Dip2a (disco interacting protein 2 homolog A) Ictidomys tridecemlineatus
Analyze
Symbol: Dip2a
Name: disco interacting protein 2 homolog A
RGD ID: 12519814
Description: ENCODES a protein that exhibits acetate-CoA ligase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process (ortholog); dendritic spine morphogenesis (ortholog); positive regulation of peptidyl-lysine acetylation (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Axenfeld-Rieger syndrome type 3 (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DIP2 disco-interacting protein 2 homolog A; disco-interacting protein 2 homolog A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497139,011,566 - 39,080,928 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493677849,122 - 123,458 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493677849,130 - 123,345 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Dip2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497139,011,566 - 39,080,928 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493677849,122 - 123,458 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493677849,130 - 123,345 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DIP2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382146,458,891 - 46,583,871 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2146,458,891 - 46,570,015 (+)EnsemblGRCh38hg38GRCh38
GRCh372147,878,804 - 47,991,139 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362146,703,318 - 46,813,028 (+)NCBINCBI36Build 36hg18NCBI36
Celera2132,992,036 - 33,103,092 (+)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2133,258,778 - 33,369,843 (+)NCBIHuRef
CHM1_12147,439,710 - 47,550,763 (+)NCBICHM1_1
T2T-CHM13v2.02144,845,016 - 44,957,436 (+)NCBIT2T-CHM13v2.0
Dip2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391076,098,581 - 76,181,194 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1076,095,263 - 76,181,125 (-)EnsemblGRCm39 Ensembl
GRCm381076,263,034 - 76,345,360 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1076,259,429 - 76,345,291 (-)EnsemblGRCm38mm10GRCm38
MGSCv371075,725,794 - 75,808,007 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361075,706,062 - 75,788,978 (-)NCBIMGSCv36mm8
Celera1077,306,976 - 77,389,563 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.76NCBI
Dip2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82012,284,037 - 12,373,519 (+)NCBIGRCr8
mRatBN7.22012,284,566 - 12,371,068 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2012,284,654 - 12,370,217 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2012,979,073 - 13,070,029 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02012,340,003 - 12,430,954 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02012,811,781 - 12,902,737 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02013,044,056 - 13,127,971 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,044,104 - 13,127,487 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02015,201,168 - 15,285,083 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42012,700,337 - 12,788,775 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2013,781,859 - 13,864,611 (+)NCBICelera
Cytogenetic Map20p12NCBI
Dip2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540742,857,344 - 42,959,265 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540742,857,297 - 42,961,831 (+)NCBIChiLan1.0ChiLan1.0
DIP2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22242,635,581 - 42,751,057 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12137,446,721 - 37,560,664 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02132,921,019 - 33,034,988 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12146,060,713 - 46,168,885 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2146,060,713 - 46,168,885 (+)Ensemblpanpan1.1panPan2
DIP2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13139,695,620 - 39,778,527 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3139,686,465 - 39,777,484 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3138,915,968 - 39,008,744 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03139,329,446 - 39,422,224 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3139,329,161 - 39,422,110 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13139,191,013 - 39,283,507 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03139,151,916 - 39,244,318 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03139,669,833 - 39,762,599 (+)NCBIUU_Cfam_GSD_1.0
DIP2A
(Sus scrofa - pig)		 No map positions available.
DIP2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1290,058,331 - 90,167,278 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl290,059,346 - 90,167,019 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605418,457,953 - 18,590,303 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dip2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474531,528,642 - 31,640,306 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474531,528,577 - 31,642,469 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000007197   ⟹   ENSSTOP00000006432
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493677849,306 - 123,408 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000022582   ⟹   ENSSTOP00000019969
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493677849,122 - 123,458 (-)Ensembl
RefSeq Acc Id: XM_021720085   ⟹   XP_021575760
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440497139,011,566 - 39,080,928 (+)NCBI
SpeTri2.0NW_00493677849,130 - 123,345 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040287180   ⟹   XP_040143114
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440497139,037,203 - 39,080,928 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021575760 (Get FASTA)   NCBI Sequence Viewer  
  XP_040143114 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000006432.3
  ENSSTOP00000019969.2
GenBank Protein KAG3284194 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021575760   ⟸   XM_021720085
- Peptide Label: isoform X1
- UniProtKB: I3M9A1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040143114   ⟸   XM_040287180
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000006432   ⟸   ENSSTOT00000007197
RefSeq Acc Id: ENSSTOP00000019969   ⟸   ENSSTOT00000022582
Protein Domains
DMAP1-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000007172 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000007197.3 UniProtKB/TrEMBL
  ENSSTOT00000022582.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.300.30 UniProtKB/TrEMBL
  3.40.50.12780 UniProtKB/TrEMBL
InterPro AMP-bd_C_sf UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/TrEMBL
  ANL_N_sf UniProtKB/TrEMBL
  Dip2-like_dom UniProtKB/TrEMBL
  DMAP1-bd UniProtKB/TrEMBL
NCBI Gene Dip2a ENTREZGENE
PANTHER DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED UniProtKB/TrEMBL
  DISCO-INTERACTING PROTEIN 2 HOMOLOG A UniProtKB/TrEMBL
Pfam AMP-binding UniProtKB/TrEMBL
  DMAP_binding UniProtKB/TrEMBL
PROSITE DMAP1_BIND UniProtKB/TrEMBL
SMART DMAP_binding UniProtKB/TrEMBL
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/TrEMBL
UniProt I3M9A1 ENTREZGENE, UniProtKB/TrEMBL
  I3N6H3_ICTTR UniProtKB/TrEMBL