Scyl2 (SCY1 like pseudokinase 2) - Rat Genome Database

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Gene: Scyl2 (SCY1 like pseudokinase 2) Ictidomys tridecemlineatus
Analyze
Symbol: Scyl2
Name: SCY1 like pseudokinase 2
RGD ID: 12518516
Description: ENCODES a protein that exhibits ATP binding (inferred); protein kinase activity (inferred); signaling receptor binding (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); ASSOCIATED WITH arthrogryposis multiplex congenita-4 (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SCY1 like pseudokinase 2, transcript variant X1; SCY1 like pseudokinase 2, transcript variant X2; SCY1 like pseudokinase 2, transcript variant X3; SCY1 like pseudokinase 2, transcript variant X4; SCY1-like 2; SCY1-like protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494520,492,420 - 20,554,460 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649213,501,663 - 13,564,867 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649213,502,854 - 13,564,886 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Scyl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494520,492,420 - 20,554,460 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649213,501,663 - 13,564,867 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649213,502,854 - 13,564,886 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCYL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812100,267,177 - 100,341,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12100,267,140 - 100,341,715 (+)EnsemblGRCh38hg38GRCh38
GRCh3712100,660,955 - 100,735,493 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361299,185,680 - 99,258,048 (+)NCBINCBI36Build 36hg18NCBI36
Build 341299,164,016 - 99,236,380NCBI
Celera12100,326,815 - 100,399,182 (+)NCBICelera
Cytogenetic Map12q23.1NCBI
HuRef1297,722,877 - 97,795,047 (+)NCBIHuRef
CHM1_112100,627,192 - 100,699,929 (+)NCBICHM1_1
T2T-CHM13v2.012100,228,403 - 100,303,144 (+)NCBIT2T-CHM13v2.0
Scyl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391089,474,582 - 89,522,179 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1089,474,583 - 89,522,147 (-)EnsemblGRCm39 Ensembl
GRCm381089,638,720 - 89,686,317 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1089,638,721 - 89,686,285 (-)EnsemblGRCm38mm10GRCm38
MGSCv371089,102,852 - 89,149,030 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361089,069,906 - 89,116,084 (-)NCBIMGSCv36mm8
Celera1091,640,299 - 91,687,002 (-)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1045.05NCBI
Scyl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8725,951,734 - 26,004,663 (-)NCBIGRCr8
mRatBN7.2724,064,404 - 24,117,338 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl724,064,404 - 24,117,305 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx726,058,920 - 26,111,817 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0728,221,349 - 28,274,181 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0727,998,664 - 28,051,565 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0730,291,087 - 30,344,464 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl730,291,087 - 30,344,445 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0730,387,991 - 30,441,350 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4726,429,923 - 26,483,533 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1726,451,520 - 26,503,820 (-)NCBI
Celera721,207,836 - 21,260,716 (-)NCBICelera
Cytogenetic Map7q13NCBI
Scyl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540535,984,667 - 36,043,628 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540535,984,667 - 36,043,581 (+)NCBIChiLan1.0ChiLan1.0
SCYL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210108,333,141 - 108,404,856 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112108,329,559 - 108,401,253 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01297,848,852 - 97,920,561 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112101,255,169 - 101,326,808 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12101,255,412 - 101,326,808 (+)Ensemblpanpan1.1panPan2
SCYL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11539,365,702 - 39,429,979 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1539,365,157 - 39,428,085 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1539,744,679 - 39,808,502 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01540,028,775 - 40,093,229 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1540,028,228 - 40,093,033 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11539,286,373 - 39,350,816 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01539,392,749 - 39,457,180 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01539,666,912 - 39,731,343 (+)NCBIUU_Cfam_GSD_1.0
SCYL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl583,813,206 - 83,878,760 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1583,813,207 - 83,878,766 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2588,004,752 - 88,052,916 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCYL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11195,582,856 - 95,655,974 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037149,389,158 - 149,462,368 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Scyl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247507,412,869 - 7,477,965 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000011755   ⟹   ENSSTOP00000010546
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493649213,501,663 - 13,564,867 (-)Ensembl
RefSeq Acc Id: XM_005322377   ⟹   XP_005322434
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494520,492,420 - 20,554,459 (-)NCBI
SpeTri2.0NW_00493649213,502,854 - 13,564,886 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021724486   ⟹   XP_021580161
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494520,492,420 - 20,554,459 (-)NCBI
SpeTri2.0NW_00493649213,502,854 - 13,564,886 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021724487   ⟹   XP_021580162
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494520,492,420 - 20,554,177 (-)NCBI
SpeTri2.0NW_00493649213,502,854 - 13,564,605 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021724488   ⟹   XP_021580163
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494520,492,420 - 20,554,460 (-)NCBI
SpeTri2.0NW_00493649213,502,854 - 13,564,886 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005322434   ⟸   XM_005322377
- Peptide Label: isoform X2
- UniProtKB: I3MHX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021580163   ⟸   XM_021724488
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021580161   ⟸   XM_021724486
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021580162   ⟸   XM_021724487
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSTOP00000010546   ⟸   ENSSTOT00000011755
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011753 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011755.3 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
NCBI Gene Scyl2 ENTREZGENE
PANTHER SCY1-LIKE PROTEIN 2 UniProtKB/TrEMBL
  SCY1-RELATED S/T PROTEIN KINASE-LIKE UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt I3MHX8 ENTREZGENE, UniProtKB/TrEMBL