Srp19 (signal recognition particle 19)

Gene: Srp19 (signal recognition particle 19) Ictidomys tridecemlineatus

Analyze

Symbol:

Srp19

Name:

signal recognition particle 19

RGD ID:

12518094

Description:

ENCODES a protein that exhibits ribosome binding (ortholog); INVOLVED IN SRP-dependent cotranslational protein targeting to membrane (inferred); SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition (inferred); ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nuclear body (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	154,580,657 - 154,587,218 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936531	7,024,143 - 7,031,692 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936531	7,024,358 - 7,031,139 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

familial adenomatous polyposis 1 (ISO)

genetic disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Neurodevelopmental Disorders (ISO)

Shwachman-Diamond syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

SRP-dependent cotranslational protein targeting to membrane (IEA)

SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

nuclear body (IEA)

nucleolus (IEA)

signal recognition particle (IEA)

signal recognition particle, endoplasmic reticulum targeting (IEA)

Molecular Function

7S RNA binding (IEA)

protein binding (ISO)

ribosome binding (IEA,ISO)

RNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Srp19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	154,580,657 - 154,587,218 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936531	7,024,143 - 7,031,692 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936531	7,024,358 - 7,031,139 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SRP19
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	112,861,287 - 112,898,371 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	112,861,188 - 112,898,371 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	112,196,984 - 112,234,068 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	112,224,892 - 112,231,503 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	112,224,891 - 112,231,502	NCBI
Celera	5	108,142,564 - 108,149,171 (+)	NCBI		Celera
Cytogenetic Map	5	q22.2	NCBI
HuRef	5	107,375,987 - 107,408,525 (+)	NCBI		HuRef
CHM1_1	5	111,630,190 - 111,662,066 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	113,371,827 - 113,408,903 (+)	NCBI		T2T-CHM13v2.0

Srp19
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	34,464,185 - 34,469,652 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	34,463,900 - 34,469,652 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	34,331,121 - 34,336,599 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	34,330,847 - 34,336,599 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	34,490,799 - 34,496,253 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	34,455,984 - 34,461,399 (+)	NCBI		MGSCv36	mm8
Celera	18	34,782,673 - 34,788,127 (+)	NCBI		Celera
Cytogenetic Map	18	B1	NCBI
cM Map	18	18.57	NCBI

Srp19
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	26,205,888 - 26,212,171 (+)	NCBI		GRCr8
mRatBN7.2	18	25,931,734 - 25,937,974 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	25,931,589 - 25,938,017 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	26,059,149 - 26,065,389 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	26,822,051 - 26,828,303 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	26,156,956 - 26,163,208 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	27,114,822 - 27,121,062 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	27,114,822 - 27,121,059 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	26,828,291 - 26,834,644 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	26,800,249 - 26,806,489 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	26,826,836 - 26,833,178 (+)	NCBI
Celera	18	25,673,614 - 25,679,848 (+)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

Srp19
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955418	2,551,533 - 2,558,252 (-)	NCBI	ChiLan1.0	ChiLan1.0

SRP19
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	108,117,095 - 108,148,163 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	106,271,295 - 106,301,821 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	108,221,482 - 108,251,955 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	114,024,636 - 114,031,845 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	114,024,636 - 114,031,845 (+)	Ensembl	panpan1.1		panPan2

SRP19
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	239,651 - 245,078 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	239,652 - 245,078 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	1,639,882 - 1,645,309 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	81,422 - 86,852 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	79,578 - 86,852 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	74,586 - 80,015 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	73,664 - 79,087 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	237,129 - 242,552 (-)	NCBI		UU_Cfam_GSD_1.0

SRP19
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	116,890,800 - 116,901,444 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	116,890,800 - 116,901,501 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	121,515,476 - 121,523,217 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SRP19
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	16,151,409 - 16,180,132 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666034	62,275,384 - 62,304,500 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Srp19
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624743	30,645,258 - 30,652,761 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624743	30,645,249 - 30,651,947 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005327233	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000000347 ⟹ ENSSTOP00000000311

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936531	7,024,401 - 7,030,434 (+)	Ensembl

RefSeq Acc Id:

ENSSTOT00000041353 ⟹ ENSSTOP00000032193

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936531	7,024,143 - 7,031,692 (+)	Ensembl

RefSeq Acc Id:

XM_005327233 ⟹ XP_005327290

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	154,580,657 - 154,587,218 (-)	NCBI
SpeTri2.0	NW_004936531	7,024,358 - 7,031,139 (+)	NCBI

Sequence:

show sequence

TCCGGCTGATTTTCTGTGGGCGGAGTCTGTGCTGTCTGTGGACATGGCTTGCGCCGCCTCACGG
TCCCCGGCGGACCAAGACAGGTTTATTTGTATCTATCCTGCTTATTTAAATAATAAGAAGACCA
TCGCGGAGGGAAGGAGGATCCCCATAAGTAAGGCTGTTGAAAATCCTACAGCTACAGAGATTCA
AGATGTATGCTCAGCAGTTGGACTTAATGTGTTTGTTGAGAAAAATAAAATGTACTCTAGAGAA
TGGAATCGTGATGTTCAATACAGAGGCAGAGTCCGGGTCCAGCTCAGACAGGAAGATGGCAGCC
TCTGTCTTGTACAGTTCCCATCACGTAAATCAGTAATGTTGTATGCAGCAGAAATGATACCTAA
GCTAAAAACAAGGACACAAAAAACAGGAGGTGGTGACCCAAGTCTTCAGCAAGGAGAGGGAAGT
AAAAAAGGGAAAGGAAAGAAGAAGAAATGATCTGGTATGAGCATCAAGTATGTGATCCTGCTAT
GAGAGACATGAATGAAGAAGACTTCTTTGTATCTGAGGGAAACAGCTTTTTGTTTTCATCATTT
GACTGAACTGGGAACATTTATACCTCCCATCTTCATCATCAGAGTTGACAATGAAATAAATAAA
TCAGAAGTTTGCATCTAACATTTGTACAGTATAAAAGACAAGATATTTGTTGCTTTGGAGGTTT
TGTTTTGTCTTTCAATTAAGAGGTTTTGTGGATAAAAGAATATTTTTAAATGGCAGTAGACTGT
CTCATAAGTTACTTGAAATCCTGTTTGTCCTCTATGTATGTCAGATAAATGCTTAATAAGATTT
TAAATACACATTTTGTTCATCTTTTAAGTTAATGAAATAAAATTTTCAAACTGCCTATGACTTT
TGCTTATGAAGCAATTAATGCCAGTAAAGGAGGCATTAAGAGAGTAAATAGGTAGTGTAAACTT
GGACAATGCAACCCTACAAGAGAAGAAAATGGTAACTTTTCTTATAGGGGGAGATCAATGAACA
GTCTGTAAATCATTCTTTTAATACTTTACAGTAATCGTTCAGTTTCTGGGGGTTTTGTTTGTTT
GTTTTTTCTGTAATATAGAAAGTCCTTATGCTTTAAATTTGCTGATTTTATATTATCTTAAGGG
CTGGGGTTATAGCTCAATGGTAGAGCACCTG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005327290	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000000311.3
	ENSSTOP00000032193.1
GenBank Protein	KAG3266239	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005327290 ⟸ XM_005327233
- UniProtKB:	A0A287DF68 (UniProtKB/TrEMBL), I3LWF7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MACAASRSPADQDRFICIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNVFVEK NKMYSREWNRDVQYRGRVRVQLRQEDGSLCLVQFPSRKSVMLYAAEMIPKLKTRTQKTGGGDPS LQQGEGSKKGKGKKKK hide sequence

RefSeq Acc Id:

ENSSTOP00000032193 ⟸ ENSSTOT00000041353

RefSeq Acc Id:

ENSSTOP00000000311 ⟸ ENSSTOT00000000347

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000000348	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000000347.3	UniProtKB/TrEMBL
	ENSSTOT00000041353.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.56.30	UniProtKB/TrEMBL
InterPro	Signal_recog_particle_SRP19	UniProtKB/TrEMBL
	SRP19-like_sf	UniProtKB/TrEMBL
NCBI Gene	Srp19	ENTREZGENE
PANTHER	PTHR17453	UniProtKB/TrEMBL
	SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN	UniProtKB/TrEMBL
Pfam	SRP19	UniProtKB/TrEMBL
Superfamily-SCOP	SSF69695	UniProtKB/TrEMBL
UniProt	A0A287DF68	ENTREZGENE, UniProtKB/TrEMBL
	I3LWF7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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