Marchf5 (membrane associated ring-CH-type finger 5)

Gene: Marchf5 (membrane associated ring-CH-type finger 5) Ictidomys tridecemlineatus

Analyze

Symbol:

Marchf5

Name:

membrane associated ring-CH-type finger 5

RGD ID:

12514110

Description:

ENCODES a protein that exhibits GTPase binding (inferred); transferase activity (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN positive regulation of mitochondrial fission (inferred); protein autoubiquitination (inferred); protein localization to mitochondrion (inferred); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

E3 ubiquitin-protein ligase MARCH5; E3 ubiquitin-protein ligase MARCHF5; March5

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	40,765,970 - 40,802,490 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936601	2,398,004 - 2,435,099 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936601	2,401,016 - 2,435,093 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of mitochondrial fission (IEA)

protein autoubiquitination (IEA)

protein localization to mitochondrion (IEA)

protein polyubiquitination (IEA)

regulation of mitochondrial fission (IEA)

Cellular Component

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA)

membrane (IEA)

mitochondrial outer membrane (IEA)

mitochondrion (IEA)

Molecular Function

GTPase binding (IEA)

protein binding (ISO)

transferase activity (IEA)

ubiquitin protein ligase activity (IEA)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Marchf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	40,765,970 - 40,802,490 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936601	2,398,004 - 2,435,099 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936601	2,401,016 - 2,435,093 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MARCHF5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	92,291,167 - 92,353,964 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	92,291,167 - 92,353,964 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	94,050,924 - 94,113,721 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	94,040,900 - 94,103,701 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	94,040,899 - 94,103,701	NCBI
Celera	10	87,795,448 - 87,858,230 (+)	NCBI		Celera
Cytogenetic Map	10	q23.32-q23.33	NCBI
HuRef	10	87,679,472 - 87,742,304 (+)	NCBI		HuRef
CHM1_1	10	94,332,686 - 94,395,432 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	93,173,534 - 93,236,300 (+)	NCBI		T2T-CHM13v2.0

Marchf5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	37,184,939 - 37,201,856 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	37,184,942 - 37,199,550 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	37,207,540 - 37,224,457 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	37,207,543 - 37,222,151 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	37,282,035 - 37,298,947 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	37,272,965 - 37,287,281 (+)	NCBI		MGSCv36	mm8
Celera	19	37,983,172 - 37,999,906 (+)	NCBI		Celera
Cytogenetic Map	19	C2	NCBI
cM Map	19	32.2	NCBI

Marchf5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	244,343,674 - 244,365,160 (+)	NCBI		GRCr8
mRatBN7.2	1	234,931,137 - 234,953,849 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	234,931,271 - 234,952,632 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	243,318,924 - 243,338,903 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	250,248,529 - 250,268,635 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	243,086,724 - 243,106,831 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	255,842,642 - 255,864,131 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	255,842,783 - 255,863,142 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	263,317,717 - 263,339,484 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	241,475,394 - 241,495,500 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	241,664,225 - 241,686,469 (+)	NCBI
Celera	1	232,022,556 - 232,042,663 (+)	NCBI		Celera
Cytogenetic Map	1	q53	NCBI

Marchf5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	994,163 - 1,032,426 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	994,787 - 1,032,426 (-)	NCBI	ChiLan1.0	ChiLan1.0

MARCHF5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	104,329,579 - 104,392,130 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	104,334,895 - 104,397,444 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	89,038,753 - 89,101,305 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	92,556,500 - 92,618,319 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	92,556,500 - 92,618,319 (+)	Ensembl	panpan1.1		panPan2

MARCHF5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	6,724,070 - 6,775,436 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	6,724,106 - 6,772,670 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	6,899,779 - 6,951,222 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	6,978,142 - 7,029,486 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	6,978,145 - 7,048,395 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	6,703,982 - 6,754,897 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	6,737,610 - 6,789,126 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	6,902,292 - 6,953,846 (+)	NCBI		UU_Cfam_GSD_1.0

MARCHF5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	103,871,310 - 103,927,876 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	103,871,308 - 103,924,849 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	113,384,172 - 113,437,705 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MARCHF5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	85,569,190 - 85,621,864 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	85,569,116 - 85,623,244 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	46,302,546 - 46,362,779 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Marchf5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	3,570,255 - 3,615,057 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	3,570,415 - 3,614,380 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005333732	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040272292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000005993 ⟹ ENSSTOP00000005361

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936601	2,401,352 - 2,421,203 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000034925 ⟹ ENSSTOP00000031848

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936601	2,398,004 - 2,435,099 (-)	Ensembl

RefSeq Acc Id:

XM_005333732 ⟹ XP_005333789

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	40,765,970 - 40,802,490 (-)	NCBI
SpeTri2.0	NW_004936601	2,401,016 - 2,435,093 (-)	NCBI

Sequence:

show sequence

CCTACTCCGCCGCCTCTCAGTGCTATTGTCCCTGGGCCAGGCACCGACCGGGTCCGCTGGGGAG
CGCCAAGTGCGCCGGCTCCGCGGAAGATGCCGGACCAAGCCTTACAGCAGATGCTGGACAGAAG
TTGCTGGGTTTGTTTTGCCACTGATGAAGATGATAGAACAGCTGAATGGGTGAGACCATGCAGG
TGCCGAGGATCTACCAAATGGGTTCATCAGGCTTGTCTGCAGCGCTGGGTTGATGAAAAACAAA
GAGGAAACAGTACAGCCAGAGTGGCATGCCCTCAGTGCAATGCTGAATACTTAATAGTTTTTCC
AAAGTTGGGTCCAGTTGTTTATGTCTTGGATCTTGCAGATAGACTGATCTCAAAAGCTTGTCCA
TTTGCTGCAGCAGGAATAATGGTTGGCTCTATCTATTGGACAGCTGTGACTTACGGAGCAGTAA
CAGTGATGCAGGTCGTAGGCCATAAAGAAGGGCTGGATGTTATGGAGAGAGCTGATCCTTTATT
TCTTTTAATTGGACTTCCTACTATTCCTGTCATGCTGATATTAGGCAAGATGATTCGCTGGGAG
GATTATGTGCTTAGACTATGGCGCAAATACTCAAATAAACTACAAATTTTGAACAGTATATTTC
CAGGAATTGGTTGTCCTGTTCCCCGAATTCCAGCCGAAGCTAATCCTTTAGCAGATCATGTCTC
TGCTACCCGAATTTTGTGTGGAGCCCTTGTCTTTCCTACTATTGCGACAATAGTTGGTAAACTG
ATGTTCAGTAGTGTTAACTCTAATTTACAAAGGACAATCTTGGGTGGAATTGCTTTTGTTGCCA
TAAAAGGAGCATTTAAGGTTTACTTCAAACAGCAGCAATATTTACGTCAGGCACACCGCAAAAT
TCTAAATTATCCAGAGCAAGAAGAAGCATAAAACTGTGACTTCTGTTTGTTCTGCAGTCCTCTC
ATCCTTATGAGTCTGTTGTGTCGTTTTGATTCCATCATTAATGCACTAGTGGAGACTTGTTATA
AGCTGCTGCTCCTATATTTTTAAGAAATATAATAAAGCACTTAGGGCAGGGGAAATCCTCTCAG
TAATCACGGAACCTAAGGATGTGATTCGTTTTCATGGTTTTGTATGTACTTCTTTTGTGGCAGT
CATCTAAACCATTATCTTAGCATGGTAAACCTGAGTTTGTTCATATTTTCTCCAGATATGTAAA
GATCAAACTGTACAAATATTAAAAATGCACATGCTGTTTTATTCTAA

hide sequence

RefSeq Acc Id:

XM_040272292 ⟹ XP_040128226

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	40,765,970 - 40,788,467 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005333789	(Get FASTA)	NCBI Sequence Viewer
	XP_040128226	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000005361.3
	ENSSTOP00000031848.1
GenBank Protein	KAG3264492	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005333789 ⟸ XM_005333732
- Peptide Label:	isoform X1
- UniProtKB:	A0A287DE71 (UniProtKB/TrEMBL), I3M734 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPDQALQQMLDRSCWVCFATDEDDRTAEWVRPCRCRGSTKWVHQACLQRWVDEKQRGNSTARVA CPQCNAEYLIVFPKLGPVVYVLDLADRLISKACPFAAAGIMVGSIYWTAVTYGAVTVMQVVGHK EGLDVMERADPLFLLIGLPTIPVMLILGKMIRWEDYVLRLWRKYSNKLQILNSIFPGIGCPVPR IPAEANPLADHVSATRILCGALVFPTIATIVGKLMFSSVNSNLQRTILGGIAFVAIKGAFKVYF KQQQYLRQAHRKILNYPEQEEA hide sequence

RefSeq Acc Id:	XP_040128226 ⟸ XM_040272292
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSSTOP00000031848 ⟸ ENSSTOT00000034925

RefSeq Acc Id:

ENSSTOP00000005361 ⟸ ENSSTOT00000005993

Protein Domains

RING-CH-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000005998	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000005993.3	UniProtKB/TrEMBL
	ENSSTOT00000034925.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
InterPro	Znf_RING-CH	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
NCBI Gene	March5	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE MARCH5	UniProtKB/TrEMBL
	E3 UBIQUITIN-PROTEIN LIGASE MARCHF5	UniProtKB/TrEMBL
Pfam	RINGv	UniProtKB/TrEMBL
PROSITE	ZF_RING_CH	UniProtKB/TrEMBL
SMART	RINGv	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
UniProt	A0A287DE71	ENTREZGENE, UniProtKB/TrEMBL
	I3M734	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-07-16	Marchf5	membrane associated ring-CH-type finger 5	March5	membrane associated ring-CH-type finger 5	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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