Nt5c (5', 3'-nucleotidase, cytosolic) - Rat Genome Database
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Gene: Nt5c (5', 3'-nucleotidase, cytosolic) Ictidomys tridecemlineatus
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Symbol: Nt5c
Name: 5', 3'-nucleotidase, cytosolic
RGD ID: 12512946
Description: ENCODES a protein that exhibits 5'-nucleotidase activity (ortholog); identical protein binding (ortholog); IMP 5'-nucleotidase activity (ortholog); INVOLVED IN dCMP catabolic process (ortholog); deoxyribonucleotide catabolic process (ortholog); dephosphorylation (ortholog); PARTICIPATES IN gemcitabine pharmacodynamics pathway; gemcitabine pharmacokinetics pathway; lamivudine pharmacokinetics pathway; ASSOCIATED WITH Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: 5'(3')-deoxyribonucleotidase, cytosolic type
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936594430,274 - 432,027 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
cytosol  (ISO)
nucleus  (ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Nt5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936594430,274 - 432,027 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NT5C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1775,130,225 - 75,131,757 (-)EnsemblGRCh38hg38GRCh38
GRCh381775,130,228 - 75,131,965 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371773,126,323 - 73,127,837 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371773,126,320 - 73,127,890 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361770,637,918 - 70,639,472 (-)NCBINCBI36hg18NCBI36
Build 341770,637,918 - 70,639,472NCBI
Celera1769,718,700 - 69,720,253 (-)NCBI
Cytogenetic Map17q25.1NCBI
HuRef1768,536,008 - 68,537,577 (-)NCBIHuRef
CHM1_11773,190,820 - 73,192,389 (-)NCBICHM1_1
Nt5c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911115,381,246 - 115,382,896 (-)NCBIGRCm39mm39
GRCm3811115,490,420 - 115,492,070 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11115,490,420 - 115,491,862 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711115,351,739 - 115,353,128 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611115,306,515 - 115,307,904 (-)NCBImm8
Celera11127,257,296 - 127,258,685 (-)NCBICelera
Cytogenetic Map11E2NCBI
Nt5c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.210100,739,591 - 100,742,276 (-)NCBI
Rnor_6.0 Ensembl10104,052,831 - 104,054,805 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.010104,052,807 - 104,054,805 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010104,225,988 - 104,227,164 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410105,574,754 - 105,576,848 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1099,314,518 - 99,316,243 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Nt5c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555532,011,738 - 2,013,443 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555532,011,549 - 2,014,209 (-)NCBIChiLan1.0ChiLan1.0
NT5C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11774,632,846 - 74,634,136 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01769,077,021 - 69,078,998 (-)NCBIMhudiblu_PPA_v0panPan3
NT5C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl95,343,378 - 5,344,380 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.195,342,793 - 5,344,432 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
NT5C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl126,139,439 - 6,164,142 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1126,162,420 - 6,164,143 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2126,124,412 - 6,126,605 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NT5C
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11646,531,820 - 46,533,763 (+)NCBI
ChlSab1.1 Ensembl1646,532,216 - 46,535,736 (+)Ensembl
Nt5c
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248014,952,736 - 4,954,660 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005332546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGTP01070489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005332546   ⟹   XP_005332603
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_004936594430,274 - 432,027 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005332603 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005332603   ⟸   XM_005332546
- UniProtKB: I3MP97 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015167 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000013588 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015166 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1000 UniProtKB/TrEMBL
InterPro 5'(3')-deoxyribonucleotidase UniProtKB/TrEMBL
  HAD-like_sf UniProtKB/TrEMBL
  HAD_sf UniProtKB/TrEMBL
NCBI Gene Nt5c ENTREZGENE
Pfam NT5C UniProtKB/TrEMBL
Superfamily-SCOP SSF56784 UniProtKB/TrEMBL
UniProt I3MP97 ENTREZGENE, UniProtKB/TrEMBL