Gls (glutaminase) - Rat Genome Database

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Gene: Gls (glutaminase) Ictidomys tridecemlineatus
Analyze
Symbol: Gls
Name: glutaminase
RGD ID: 12512102
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); glutamine catabolic process (ortholog); regulation of respiratory gaseous exchange by nervous system process (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 71 (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN mitochondrion (inferred); synapse (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutaminase kidney isoform, mitochondrial; glutaminase, transcript variant X1; glutaminase, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303149,524,201 - 149,600,982 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365067,237,099 - 7,313,976 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365067,237,099 - 7,314,011 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gls
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303149,524,201 - 149,600,982 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365067,237,099 - 7,313,976 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365067,237,099 - 7,314,011 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382190,880,821 - 190,965,552 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2190,880,821 - 190,965,552 (+)EnsemblGRCh38hg38GRCh38
GRCh372191,745,547 - 191,830,278 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362191,453,792 - 191,538,021 (+)NCBINCBI36Build 36hg18NCBI36
Build 342191,571,102 - 191,655,771NCBI
Celera2185,340,136 - 185,424,375 (+)NCBICelera
Cytogenetic Map2q32.2NCBI
HuRef2183,605,181 - 183,689,941 (+)NCBIHuRef
CHM1_12191,751,387 - 191,836,127 (+)NCBICHM1_1
T2T-CHM13v2.02191,369,931 - 191,454,659 (+)NCBIT2T-CHM13v2.0
Gls
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39152,202,608 - 52,274,168 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl152,202,607 - 52,272,391 (-)EnsemblGRCm39 Ensembl
GRCm38152,163,449 - 52,235,009 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl152,163,448 - 52,233,232 (-)EnsemblGRCm38mm10GRCm38
MGSCv37152,220,293 - 52,290,076 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36152,110,128 - 52,177,777 (-)NCBIMGSCv36mm8
Celera152,701,920 - 52,771,737 (-)NCBICelera
Cytogenetic Map1C1.1NCBI
cM Map126.86NCBI
Gls
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8956,836,584 - 56,908,861 (+)NCBIGRCr8
mRatBN7.2949,344,616 - 49,416,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl949,344,781 - 49,416,900 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx957,894,412 - 57,966,467 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0963,017,246 - 63,089,303 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0961,313,233 - 61,385,290 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0954,212,622 - 54,284,879 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl954,212,767 - 54,284,872 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0953,923,145 - 53,995,543 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4946,380,165 - 46,452,974 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1946,381,578 - 46,454,381 (+)NCBI
Celera947,008,653 - 47,080,221 (+)NCBICelera
Cytogenetic Map9q22NCBI
Gls
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554038,195,255 - 8,261,402 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554038,195,241 - 8,261,402 (-)NCBIChiLan1.0ChiLan1.0
GLS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21393,562,487 - 93,647,465 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B93,577,451 - 93,662,449 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B78,182,117 - 78,267,071 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B196,098,910 - 196,183,332 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B196,098,910 - 196,183,323 (+)Ensemblpanpan1.1panPan2
GLS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1371,433,640 - 1,508,347 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl371,433,398 - 1,508,146 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha372,381,805 - 2,456,538 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0371,321,277 - 1,395,855 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl371,321,033 - 1,397,358 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1371,330,931 - 1,405,450 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0371,298,679 - 1,373,454 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0371,327,448 - 1,402,011 (+)NCBIUU_Cfam_GSD_1.0
GLS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1595,513,446 - 95,598,311 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11595,513,414 - 95,606,029 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215106,832,208 - 106,866,986 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GLS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11076,402,201 - 76,489,063 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1076,402,195 - 76,486,498 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040122,988,383 - 123,074,691 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gls
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248545,108,566 - 5,202,240 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248545,106,419 - 5,202,445 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000029897   ⟹   ENSSTOP00000018623
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365067,237,099 - 7,313,976 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000032274   ⟹   ENSSTOP00000031075
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365067,268,098 - 7,313,615 (-)Ensembl
RefSeq Acc Id: XM_005324368   ⟹   XP_005324425
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303149,524,201 - 149,600,652 (+)NCBI
SpeTri2.0NW_0049365067,237,099 - 7,313,836 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005324369   ⟹   XP_005324426
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303149,524,457 - 149,572,422 (+)NCBI
SpeTri2.0NW_0049365067,265,650 - 7,314,011 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040294608   ⟹   XP_040150542
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303149,537,622 - 149,600,982 (+)NCBI
RefSeq Acc Id: XM_040294609   ⟹   XP_040150543
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303149,555,752 - 149,600,982 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005324425   ⟸   XM_005324368
- Peptide Label: isoform X1
- UniProtKB: I3N2M7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005324426   ⟸   XM_005324369
- Peptide Label: isoform X2
- UniProtKB: A0A287DBX9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040150542   ⟸   XM_040294608
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040150543   ⟸   XM_040294609
- Peptide Label: isoform X4
RefSeq Acc Id: ENSSTOP00000018623   ⟸   ENSSTOT00000029897
RefSeq Acc Id: ENSSTOP00000031075   ⟸   ENSSTOT00000032274
Protein Domains
Glutaminase EF-hand


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000028716 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000029897.2 UniProtKB/TrEMBL
  ENSSTOT00000032274.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.238.210 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
  3.40.710.10 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  Beta-lactam/transpept-like UniProtKB/TrEMBL
  Glutaminase UniProtKB/TrEMBL
  Glutaminase_EF-hand UniProtKB/TrEMBL
NCBI Gene Gls ENTREZGENE
PANTHER GLUTAMINASE KIDNEY ISOFORM, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR12544 UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  EF-hand_14 UniProtKB/TrEMBL
  Glutaminase UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
  SSF56601 UniProtKB/TrEMBL
UniProt A0A287DBX9 ENTREZGENE, UniProtKB/TrEMBL
  I3N2M7 ENTREZGENE, UniProtKB/TrEMBL