Septin1 (septin 1) - Rat Genome Database

Name: Septin1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Septin1 (septin 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Septin1

Name:

septin 1

RGD ID:

12510323

Description:

ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); identical protein binding (inferred); INVOLVED IN meiotic metaphase chromosome alignment (ortholog); spindle assembly involved in female meiosis (ortholog); FOUND IN cell division site (inferred); cytoskeleton (inferred); meiotic spindle (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Sept1; septin-1

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SEPTIN1 (septin 1)	NCBI	Ortholog
Mus musculus (house mouse):	Septin1 (septin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Septin1 (septin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Septin1 (septin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SEPTIN1 (septin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SEPTIN1 (septin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SEPTIN1 (septin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SEPTIN1 (septin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Septin1 (septin 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	124,749,372 - 124,762,085 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	12,843,820 - 12,851,032 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	12,847,236 - 12,852,963 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cytoskeleton-dependent cytokinesis (IEA)

meiotic metaphase chromosome alignment (IEA,ISO)

regulation of exocytosis (IEA)

spindle assembly involved in female meiosis (IEA,ISO)

Cellular Component

cell division site (IEA)

cytoskeleton (IEA)

meiotic spindle (IEA)

microtubule cytoskeleton (IEA)

midbody (IEA)

septin complex (IEA)

septin ring (IEA)

synaptic vesicle (IEA)

Molecular Function

GTP binding (IEA)

GTPase activity (IEA)

identical protein binding (IEA)

molecular adaptor activity (IEA)

nucleotide binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Septin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	124,749,372 - 124,762,085 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936501	12,843,820 - 12,851,032 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936501	12,847,236 - 12,852,963 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SEPTIN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	30,378,135 - 30,382,815 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	30,378,135 - 30,395,991 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	30,389,456 - 30,394,136 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	30,296,957 - 30,301,672 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	30,296,957 - 30,301,672	NCBI
Celera	16	29,904,429 - 29,909,188 (+)	NCBI		Celera
Cytogenetic Map	16	p11.2	NCBI
HuRef	16	27,951,218 - 27,955,945 (-)	NCBI		HuRef
CHM1_1	16	31,706,508 - 31,711,226 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	30,764,338 - 30,769,019 (-)	NCBI		T2T-CHM13v2.0

Septin1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	126,811,881 - 126,832,157 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	126,813,619 - 126,832,302 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	127,212,709 - 127,232,985 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	127,214,447 - 127,233,130 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	134,357,956 - 134,361,959 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	127,005,598 - 127,009,601 (-)	NCBI		MGSCv36	mm8
Celera	7	127,063,210 - 127,067,214 (-)	NCBI		Celera
Cytogenetic Map	7	F3	NCBI
cM Map	7	69.39	NCBI

Septin1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	191,263,200 - 191,267,086 (-)	NCBI		GRCr8
mRatBN7.2	1	181,832,700 - 181,836,566 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	181,832,701 - 181,836,566 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	190,183,588 - 190,187,454 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	197,369,676 - 197,373,542 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	190,038,210 - 190,042,079 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	198,658,744 - 198,662,610 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	198,658,745 - 198,662,610 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	205,652,475 - 205,656,341 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	186,474,714 - 186,478,580 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	186,624,595 - 186,628,461 (-)	NCBI
Celera	1	179,484,367 - 179,488,232 (-)	NCBI		Celera
Cytogenetic Map	1	q37	NCBI

Septin1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955493	7,304,472 - 7,312,185 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955493	7,304,472 - 7,309,022 (-)	NCBI	ChiLan1.0	ChiLan1.0

SEPTIN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	33,583,330 - 33,593,399 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	38,384,787 - 38,402,163 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	24,586,711 - 24,591,587 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	30,751,869 - 30,755,133 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	30,750,665 - 30,755,345 (-)	Ensembl	panpan1.1		panPan2

SEPTIN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	17,714,929 - 17,718,972 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	17,715,408 - 17,719,159 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	19,289,544 - 19,293,553 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	17,846,389 - 17,850,406 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	17,846,585 - 17,850,402 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	17,646,593 - 17,650,610 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	17,562,034 - 17,566,041 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	17,877,697 - 17,881,714 (+)	NCBI		UU_Cfam_GSD_1.0

SEPTIN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	17,924,651 - 17,937,947 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	17,924,651 - 17,937,949 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	18,359,300 - 18,376,616 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SEPTIN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	27,055,239 - 27,059,749 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	27,055,538 - 27,059,723 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	2,461,126 - 2,465,801 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Septin1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624782	13,550,185 - 13,553,480 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624782	13,549,862 - 13,553,557 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021725510	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004404	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000002780 ⟹ ENSSTOP00000002487

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936501	12,847,245 - 12,851,032 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000039653 ⟹ ENSSTOP00000027103

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936501	12,843,820 - 12,850,923 (-)	Ensembl

RefSeq Acc Id:

XM_021725510 ⟹ XP_021581185

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409344	124,749,372 - 124,762,085 (-)	NCBI
SpeTri2.0	NW_004936501	12,847,236 - 12,852,963 (-)	NCBI

Sequence:

show sequence

GCATCTAGTATATCATTCATCAGTATCTTTAAAGACACTGGGGAATACAGAAACTGGGAAGACA
TGATCTCTGCCCTCAGAGAGCTCAGTTGGGAGCAGAGACAGGACAAGGAGTATGTGGGTTTTGC
TGCGCTCCCCAACCAGCTGCACCGCAAGTCCGTCAAGAAGGGGTTTGACTTCACACTCATGGTG
GCAGGGGAGTCAGGTCTGGGGAAATCCACCCTTATCAACAGCCTGTTCCTCACCAACCTCTATG
AGGATCGGCAAGTGCCAGAGGCTAGCGCTCGCTTGACACAAACATTGACCATTGAGCGCAGGGG
TGTGGAGATTGAAGAAGGGGGTGTCAAGGTGAAGCTGACCTTGGTGGACACACCTGGCTTTGGG
GATTCTGTGGACTGCTCAGACTGCTGGCTGCCTGTGGTGCGCTTCATTGAGGAGCAATTTGAGC
AGTATCTCAGGGACGAGAGTGGTTTGAACCGGAAGAACATCCAGGATTCCCGGGTCCACTGCTG
TCTCTACTTCATCTCACCCTTCGGCCGGGGGCTCCGGCCCCTAGATGTGGCCTTCCTTCGGGCT
GTGCACGAGAAAGTCAACATCATTCCAGTCATCGGCAAAGCAGATGCCCTGATGCCCAAGGAAA
CCCAGGCCCTCAAGCAGAAGATACGGGACCAATTGAAGGAGGAGGAGATCAATATTTACCAGTT
CCCAGAATGTGACTCTGATGAGGATGAAGACTTCAAGAGACAGGATGCTGAGATGAAGGGAAGC
ATCCCTTTCGCAGTCGTCGGTTCATGCGAGGTGGTGAGAGACGGTGGGACGCGACCAGTGAGGG
GACGCCGCTACTCCTGGGGGACCGTGGAGGTGGAGAACCCACAGCACTGCGACTTCTTGAACCT
GAGACGGATGTTGGTGCAGACACACCTGCAGGACTTGAAAGAGGTGACACACGATCTGCTCTAC
GAGGGCTACCGGGCCCGCTGCCTACAGAGCCTAGCCCGGCCTGGGGCTCGTGATCGAACCAGCC
GCAGTAAACTTTCCCGCCAGAGCGCCACAGAGATCCCGCTGCCCATGCTGCCTCTGGCCGAGAC
GGAGAAGTTGATCCGCGAGAAGGACGAAGAGCTGCGCCGCATGCAAGAGATGCTGGAGAAGATG
CAGGCCCAGATGCAGCAGAGCCAGGCTCAGGGCGAGCAGTCGGACGCTCTCTGAGGCCTCCGCC
CGGCCCGGCCTGACCTTACTTCGGCTCCGCCTTCTGTCCGTTTCTTGTCCAATCCCGGGGCCCT
AGACTGCCCAGCCTCTAATTCCGGAGCCTCCGAGTGGCCCACACCCACTCTTGCACTTGCTTTG
TGTAGGTTCTCGCGGCTAAAGGTTCAGCCCGTCCCGGAGTTTGTAGCTCCGCCCCCCACTTCGC
CCTGGGCTCACTTCCAGGAGGGGCCTCCAGCCCAGCTCTTGCCAGCCTCTCCCCATCTTGGGGT
GTCGTCCCCCTTCAAACTATGTCTCCAATAAAAACTTAGCTTCCCGGGC

hide sequence

Protein Sequences


Protein RefSeqs	XP_021581185	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000002487.3
	ENSSTOP00000027103.1
GenBank Protein	KAG3259637	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021581185 ⟸ XM_021725510

- UniProtKB:

A0A287D0K6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MISALRELSWEQRQDKEYVGFAALPNQLHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTNLY
EDRQVPEASARLTQTLTIERRGVEIEEGGVKVKLTLVDTPGFGDSVDCSDCWLPVVRFIEEQFE
QYLRDESGLNRKNIQDSRVHCCLYFISPFGRGLRPLDVAFLRAVHEKVNIIPVIGKADALMPKE
TQALKQKIRDQLKEEEINIYQFPECDSDEDEDFKRQDAEMKGSIPFAVVGSCEVVRDGGTRPVR
GRRYSWGTVEVENPQHCDFLNLRRMLVQTHLQDLKEVTHDLLYEGYRARCLQSLARPGARDRTS
RSKLSRQSATEIPLPMLPLAETEKLIREKDEELRRMQEMLEKMQAQMQQSQAQGEQSDAL

hide sequence

RefSeq Acc Id:

ENSSTOP00000027103 ⟸ ENSSTOT00000039653

RefSeq Acc Id:

ENSSTOP00000002487 ⟸ ENSSTOT00000002780

Protein Domains

Septin-type G

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000002782	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000002780.3	UniProtKB/TrEMBL
	ENSSTOT00000039653.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	G_SEPTIN_dom	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Septin	UniProtKB/TrEMBL
NCBI Gene	Sept1	ENTREZGENE
PANTHER	SEPTIN	UniProtKB/TrEMBL
	SEPTIN-1	UniProtKB/TrEMBL
Pfam	Septin	UniProtKB/TrEMBL
PIRSF	Septin	UniProtKB/TrEMBL
PROSITE	G_SEPTIN	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A287D0K6	ENTREZGENE, UniProtKB/TrEMBL
	I3M134_ICTTR	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-04-09	Septin1	septin 1	Sept1		Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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