Vps41 (VPS41 subunit of HOPS complex)

Gene: Vps41 (VPS41 subunit of HOPS complex) Ictidomys tridecemlineatus

Analyze

Symbol:

Vps41

Name:

VPS41 subunit of HOPS complex

RGD ID:

12508999

Description:

ENCODES a protein that exhibits obsolete protein self-association (ortholog); INVOLVED IN Golgi vesicle transport (ortholog); regulated exocytosis (ortholog); ASSOCIATED WITH autosomal recessive spinocerebellar ataxia 29 (ortholog); genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN AP-3 adaptor complex (ortholog); clathrin complex (ortholog); cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

vacuolar protein sorting-associated protein 41 homolog; VPS41, HOPS complex subunit; VPS41, HOPS complex subunit, transcript variant X1; VPS41, HOPS complex subunit, transcript variant X2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	95,084,728 - 95,242,966 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	14,293,108 - 14,454,707 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936478	14,296,191 - 14,454,650 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive spinocerebellar ataxia 29 (ISO)

genetic disease (ISO)

pleomorphic xanthoastrocytoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to starvation (IEA)

endosomal vesicle fusion (IEA)

endosome to lysosome transport (IEA)

Golgi vesicle transport (ISO)

intracellular protein transport (IEA)

late endosome to lysosome transport (IEA)

macroautophagy (IEA)

protein targeting to vacuole (IEA)

protein transport (IEA)

regulated exocytosis (ISO)

vesicle-mediated transport (IEA)

Cellular Component

AP-3 adaptor complex (IEA,ISO)

clathrin complex (IEA,ISO)

clathrin-coated vesicle (IEA)

cytosol (ISO)

early endosome (IEA)

early endosome membrane (IEA)

endomembrane system (IEA)

endosome (IEA)

endosome membrane (IEA)

Golgi apparatus (IEA)

Golgi-associated vesicle (ISO)

HOPS complex (IEA)

intracellular organelle (IEA)

late endosome (IEA)

late endosome membrane (IEA)

lysosomal HOPS complex (IEA)

lysosomal membrane (IEA)

lysosome (IEA)

membrane (ISO)

microtubule cytoskeleton (IEA)

Molecular Function

identical protein binding (IEA)

microtubule binding (IEA)

obsolete protein self-association (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Vps41
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	95,084,728 - 95,242,966 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	14,293,108 - 14,454,707 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936478	14,296,191 - 14,454,650 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

VPS41
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	38,722,974 - 38,909,191 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	38,722,974 - 38,932,394 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	38,762,574 - 38,948,791 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	38,730,068 - 38,915,325 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	38,538,394 - 38,682,088	NCBI
Celera	7	38,751,388 - 38,936,638 (-)	NCBI		Celera
Cytogenetic Map	7	p14.1	NCBI
HuRef	7	38,647,724 - 38,832,980 (-)	NCBI		HuRef
CHM1_1	7	38,766,111 - 38,951,374 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	38,880,029 - 39,066,224 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	38,801,230 - 38,986,499 (-)	NCBI

Vps41
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	18,901,462 - 19,050,981 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	18,901,456 - 19,050,981 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	18,717,292 - 18,866,811 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	18,717,286 - 18,866,811 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	18,809,161 - 18,958,680 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	18,724,764 - 18,874,268 (+)	NCBI		MGSCv36	mm8
Celera	13	19,025,759 - 19,178,125 (+)	NCBI		Celera
Cytogenetic Map	13	A2	NCBI
cM Map	13	6.75	NCBI

Vps41
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	50,758,732 - 50,923,129 (-)	NCBI		GRCr8
mRatBN7.2	17	46,063,132 - 46,227,533 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	46,063,124 - 46,227,791 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	17	49,259,125 - 49,416,986 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	53,262,047 - 53,419,908 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	47,372,921 - 47,531,055 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	48,643,754 - 48,810,633 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	48,648,879 - 48,810,991 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	46,702,308 - 46,866,329 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	53,893,474 - 54,063,005 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	17	42,165,613 - 42,324,736 (-)	NCBI		Celera
Cytogenetic Map	17	q11	NCBI

Vps41
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955460	4,555,870 - 4,749,153 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955460	4,555,870 - 4,749,154 (+)	NCBI	ChiLan1.0	ChiLan1.0

VPS41
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	43,554,730 - 43,762,833 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	91,879,465 - 92,087,568 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	39,355,578 - 39,543,281 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	39,589,893 - 39,776,992 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	39,590,587 - 39,776,937 (-)	Ensembl	panpan1.1		panPan2

VPS41
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	10,788,846 - 10,956,207 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	10,788,891 - 10,955,645 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	10,636,490 - 10,810,220 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	10,838,609 - 11,006,057 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	10,838,645 - 11,006,057 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	10,810,095 - 10,983,580 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	10,784,236 - 10,951,239 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	10,899,366 - 11,067,148 (+)	NCBI		UU_Cfam_GSD_1.0

VPS41
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	55,301,624 - 55,466,628 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	55,293,655 - 55,466,628 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	60,565,808 - 60,729,840 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

VPS41
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	19,629,271 - 19,814,360 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	19,629,282 - 19,817,649 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666062	2,573,777 - 2,779,166 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Vps41
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	22,121,571 - 22,299,193 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624740	22,121,772 - 22,297,514 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005319206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013355978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000007372 ⟹ ENSSTOP00000006585

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936478	14,297,102 - 14,423,318 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000037628 ⟹ ENSSTOP00000027459

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936478	14,293,108 - 14,454,707 (-)	Ensembl

RefSeq Acc Id:

XM_005319206 ⟹ XP_005319263

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	95,084,728 - 95,242,966 (-)	NCBI
SpeTri2.0	NW_004936478	14,296,191 - 14,454,650 (-)	NCBI

Sequence:

show sequence

TGACCGTACGGCGGCACCATGGCGGAAGCAGAAGAGCAGGAAACTGGGTCTCTTGAAGAATCTA
CCGATGAGTCTGAGGAAGAAGAGAGTGAAGAGGAACCCAAACTGAAGTATGAAAGGCTTTCCAA
TGGGGTAACTGAAATTCTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGATAAGTTTTTG
GCACTGGGCACACATTATGGCAAGGTTTATTTACTTGATGTCCAGGGAAACATCACTCAGAAGT
TTGATGTAAGTCCTGTGAAGATAAATCAGATTAGCCTGGATGAAAGCGGAGAGCACATGGGCGT
GTGTTCAGAGGATGGCAAGGTTCAAGTATTTGGATTATATTCTGGAGAAGAATTTCATGAGACT
TTTGACTGTCCTATTAAAATCATTGCTGTACACCCACATTTTGTGAGATCCAGTTGCAAGCAGT
TTGTGACTGGAGGGAAGAAGTTGCTGCTCTTTGAACGGTCCTGGATGAACAGATGGAAGTCTTC
GGTTCTGCATGAAGGGGAAGGGAACATACGGAGTGTGAAATGGAGAGGCCATCTGATCGCTTGG
GCCAATAATATGGGTGTGAAGATTTTTGACATTACCTCAAAACAAAGAATCACCAATGTGCCCC
GGGATGATATAAGTCTTCGCCCAGATATGTATCCCTGCAGCCTCTGCTGGAAGGACAATGTGAC
ACTGATTATTGGCTGGGGGACTTCTGTTAAGATATGCTCAGTGAAGGAACGGCATGCCAGTGAA
ATGAGGGATTTGCCAAGTCGATATGTTGAAATAGTGTCTCAGTTTGAAACTGAATTCCACATCA
GTGGACTCGCCCCTCTCTGTGATCAGCTTGTTGTACTTTCCTACGTAAAAGAGGTTTCAGAAAA
AACGGAAAGAGAATATTGTGCCAGACCTAGATTGGATATCATCCAGCCACTTTCTGAGACTTGT
GAAGAGATCTCTTCTGATGCTTTGACAGTCAGAGGTTTTCAGGAGAATGAATGTAGAGATTATC
ATTTAGAATACTCTGAAGGGGAATCACTCTTCTACATCGTGAGTCCAAGAGATGTTGTAGTAGC
CAAGGAACGAGACCAAGATGATCACATCGACTGGCTCCTTGAAAAGAAGAAATATGAAGAAGCT
TTGATGGCAGCTGAAATTAGCCAAAGGAACATAAAAAGACATAAGATTCTGGATATCGGCTTGG
CATATATAAATCACTTGGTGGAGAGAGGAGAATATGACATAGCAGCACGCAAATGCCAGAAAAT
CCTTGGGAAAAATGCAGCCCTCTGGGAATACGAAGTTTATAAATTTAAAGAAATTGGACAGCTT
AAGGCTGTTAGTCCTTATTTGCCAAGAGGAGATCCAGTTCTGAAGCCACTCATATATGAAATGG
TCTTACATGAGTTTTTGGAAAGTGATTATGAGGGTTTTGCTACACTGATCCGAGAATGGCCTGG
AGATCTGTACAACAATTCAGTAATAGTTCAAGCAGTTCGAGACCACCTGAAGAAAGATAGTCAG
AACAAGACTTTACTCAAAACCCTGGCTGAATTGTATACCTATGACAAAAACTATGGCAATGCTC
TGGAAATATACTTAACATTAAGACATAAAGACGTTTTCCAACTGATACACAAGCATAATCTTTT
CAGTTCAATCAAGGATAAAATAGTTTTATTAATGGATTTTGATTCAGAGAAAGCTGTTGACATG
CTTTTGGACAATGAAGATAAAATTTCAATTAAAAAGGTAGTGGAAGAATTAGAAGACAGACCGG
AGTTACAGCATGTGTATTTGCATAAACTCTTCAAGAGAGACCATCATAAAGGGCAGCGCTACCA
TGAAAAACAGATCAGTCTTTATGCTGAGTATGATCGACCAAACTTACTACCTTTTCTCCGAGAT
AGTACCCATTGCCCACTTGAAAAGGCTCTTGAGATCTGTCAGCAGAGAAATTTTGTAGAAGAGA
CAGTGTATCTTCTAAGCAGGATGGGCAATAGCCGAAGTGCCCTGAAGATGATTATGGAGGAGTT
GCATGATGTTGATAAAGCAATTGAATTTGCCAAGGAGCAAGATGATGGAGAACTCTGGGAAGAT
CTAATTTTATATTCCATTGACAAACCACCATTTATTACTGGCTTATTGAACAATATTGGCACCC
ATGTTGATCCAATTCTGCTGATTCACCGTATTAAGGAAGGAATGGAGATTCCCAATCTGAGAGA
TTCCTTAGTTAAAATATTGCAAGACTACAATTTGCAAATTCTGCTTCGTGAAGGCTGCAAGAAG
ATTCTCGTAGCCGACTCCTTGTCCTTACTGAAGAAAATGCACCGAACTCAAATGAAAGGTGTTC
TGGTTGATGAGGAGAATATCTGTGAGTCGTGTCTTTCCCCCATCCTTCCTACTGATGCAGCAAA
GCCCTTCAGTGTGGTAGTCTTCCATTGCCGGCACATGTTCCACAAAGAGTGCTTGCCTGTCCCT
AGCATGAACTCTCCTACACAATACTGCAACATCTGCAGCGCAAAGAACCGTGGACCAGGAAGTG
CAATTTTGGAGATGAAAAAATAGCACAGCTCTGCTTGTCAGTCTCTTCTTGCTGCTCTTTTTAA
TACTGTTCTTGAAACAAGTGTGTGTTAGCACCAGTGATGATGAGATTTATTTATGTGTATAACA
GTTTCTACATCCATGCCCGTCTTCTAGAGATTTTTCTTTGTAGTTGATAAAGAAGTTGGGTTCA
TAGTCATTATTTCGTCATTTGTTTGGCTCATTGTTTAACAATGAAAATGTAAGTCTCAAAGGTA
GAAATGAATGTTTTAGAACGTAGTAATACTGTTCAACCATAAAGTGGACTACTGAGAATTGCCC
CAGCTATCAGAGAACATTGTCAACTGTGATTATCCAGCAAACTCCTACCCACAACTTGGACCTC
GTTTCCACATGCTTTGCTGGCAACAGTTACTGCATTCTAGGGTTGGCTTTCTTTATGTCATCAA
CTGTAGTTATTGTCCTAATAAGCGTTTAATGAAACATTGTGCAAACTGTCATTCATTCATTGAC
ATCTGGGAATATCATCAGCAGGCTAATGTCCTGCAGCTTTATGTTAACTAATCACATGTTCTGT
GTGTTCTTACAACTATTAGAGTATCTGGCTCTTTCAGTCACTCAGCATTTGTTGACTGAATAAA
TGTTACGTGTTTTTCATTGTGAAAGACTCATTTTTACTGGATTGAACTGCAATTGAGAAGTCAA
GCACCTTGGTAAAGAACAGAAGAGAGGTTCAGCATCTTATTATCTGAGGGATTGTGATTAGTTT
TTTCTAGTAGGGAGGAAAGGAGTGACCCTGTCCAAACCAGGGAAGGAGTCTCAGGAGAAATAGT
ATTGGTCTAATACCAGAGGATGGGCATAATTATGATATTCCTTTTCAAAGCCTTCCATGGATCC
TCCTCAAAGAACAAAGAATATAATGGAGAGAATTCAAA

hide sequence

RefSeq Acc Id:

XM_013355978 ⟹ XP_013211432

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	95,084,728 - 95,242,966 (-)	NCBI
SpeTri2.0	NW_004936478	14,296,191 - 14,454,650 (-)	NCBI

Sequence:

show sequence

TGACCGTACGGCGGCACCATGGCGGAAGCAGAAGAGCAGGAAACTGGGTCTCTTGAAGAATCTA
CCGATGAGTCTGAGGAAGAAGAGAGTGAAGAGGAACCCAAACTGAAGTATGAAAGGCTTTCCAA
TGGGGTAACTGAAATTCTTCAGAAGGATGCAGCTAGCTGCATGACAGTCCATGATAAGTTTTTG
GCACTGGGCACACATTATGGCAAGGTTTATTTACTTGATGTCCAGGGAAACATCACTCAGAAGT
TTGATGTAAGTCCTGTGAAGATAAATCAGATTAGCCTGGATGAAAGCGGAGAGCACATGGGCGT
GTGTTCAGAGGATGGCAAGGTTCAAGTATTTGGATTATATTCTGGAGAAGAATTTCATGAGACT
TTTGACTGTCCTATTAAAATCATTGCTGTACACCCACATTTTGTGAGATCCAGTTGCAAGCAGT
TTGTGACTGGAGGGAAGAAGTTGCTGCTCTTTGAACGGTCCTGGATGAACAGATGGAAGTCTTC
GGTTCTGCATGAAGGGGAAGGGAACATACGGAGTGTGAAATGGAGAGGCCATCTGATCGCTTGG
GCCAATAATATGGGTGTGAAGATTTTTGACATTACCTCAAAACAAAGAATCACCAATGTGCCCC
GGGATGATATAAGTCTTCGCCCAGATATGTATCCCTGCAGCCTCTGCTGGAAGGACAATGTGAC
ACTGATTATTGGCTGGGGGACTTCTGTTAAGATATGCTCAGTGAAGGAACGGCATGCCAGTGAA
ATGAGGGATTTGCCAAGTCGATATGTTGAAATAGTGTCTCAGTTTGAAACTGAATTCCACATCA
GTGGACTCGCCCCTCTCTGTGATCAGCTTGTTGTACTTTCCTACGTAAAAGAGGTTTCAGAAAA
AACGGAAAGAGAATATTGTGCCAGACCTAGATTGGATATCATCCAGCCACTTTCTGAGACTTGT
GAAGAGATCTCTTCTGATGCTTTGACAGTCAGAGGTTTTCAGGAGAATGAATGTAGAGATTATC
ATTTAGAATACTCTGAAGGGGAATCACTCTTCTACATCGTGAGTCCAAGAGATGTTGTAGTAGC
CAAGGAACGAGACCAAGATGATCACATCGACTGGCTCCTTGAAAAGAAGAAATATGAAGAAGCT
TTGATGGCAGCTGAAATTAGCCAAAGGAACATAAAAAGACATAAGATTCTGGATATCGGCTTGG
CATATATAAATCACTTGGTGGAGAGAGGAGAATATGACATAGCAGCACGCAAATGCCAGAAAAT
CCTTGGGAAAAATGCAGCCCTCTGGGAATACGAAGTTTATAAATTTAAAGAAATTGGACAGCTT
AAGGCTGTTAGTCCTTATTTGCCAAGAGGAGATCCAGTTCTGAAGCCACTCATATATGAAATGG
TCTTACATGAGTTTTTGGAAAGTGATTATGAGGGTTTTGCTACACTGATCCGAGAATGGCCTGG
AGATCTGTACAACAATTCAGTAATAGTTCAAGCAGTTCGAGACCACCTGAAGAAAGATAGTCAG
AACAAGACTTTACTCAAAACCCTGGCTGAATTGTATACCTATGACAAAAACTATGGCAATGCTC
TGGAAATATACTTAACATTAAGACATAAAGACGTTTTCCAACTGATACACAAGCATAATCTTTT
CAGTTCAATCAAGGATAAAATAGTTTTATTAATGGATTTTGATTCAGAGAAAGCTGTTGACATG
CTTTTGGACAATGAAGATAAAATTTCAATTAAAAAGGTAGTGGAAGAATTAGAAGACAGACCGG
AGTTACAGCATGTGTATTTGCATAAACTCTTCAAGAGAGACCATCATAAAGGGCAGCGCTACCA
TGAAAAACAGATCAGTCTTTATGCTGAGTATGATCGACCAAACTTACTACCTTTTCTCCGAGAT
AGTACCCATTGCCCACTTGAAAAGGCTCTTGAGATCTGTCAGCAGAGAAATTTTGTAGAAGAGA
CAGTGTATCTTCTAAGCAGGATGGGCAATAGCCGAAGTGCCCTGAAGATGATTATGGAGGAGTT
GCATGATGTTGATAAAGCAATTGAATTTGCCAAGGAGCAAGATGATGGAGAACTCTGGGAAGAT
CTAATTTTATATTCCATTGACAAACCACCATTTATTACTGGCTTATTGAACAATATTGGCACCC
ATGTTGATCCAATTCTGCTGATTCACCGTATTAAGGAAGGAATGGAGATTCCCAATCTGAGAGA
TTCCTTAGTTAAAATATTGCAAGACTACAATTTGCAAATTCTGCTTCGTGAAGGCTGCAAGAAG
ATTCTCGTAGCCGACTCCTTGTCCTTACTGAAGAAAATGCACCGAACTCAAATGAAAGGTGTTC
TGGTTGATGAGGAGAATATCTGTGAGTCGTGTCTTTCCCCCATCCTTCCTACTGAACTCTCCTA
CACAATACTGCAACATCTGCAGCGCAAAGAACCGTGGACCAGGAAGTGCAATTTTGGAGATGAA
AAAATAGCACAGCTCTGCTTGTCAGTCTCTTCTTGCTGCTCTTTTTAATACTGTTCTTGAAACA
AGTGTGTGTTAGCACCAGTGATGATGAGATTTATTTATGTGTATAACAGTTTCTACATCCATGC
CCGTCTTCTAGAGATTTTTCTTTGTAGTTGATAAAGAAGTTGGGTTCATAGTCATTATTTCGTC
ATTTGTTTGGCTCATTGTTTAACAATGAAAATGTAAGTCTCAAAGGTAGAAATGAATGTTTTAG
AACGTAGTAATACTGTTCAACCATAAAGTGGACTACTGAGAATTGCCCCAGCTATCAGAGAACA
TTGTCAACTGTGATTATCCAGCAAACTCCTACCCACAACTTGGACCTCGTTTCCACATGCTTTG
CTGGCAACAGTTACTGCATTCTAGGGTTGGCTTTCTTTATGTCATCAACTGTAGTTATTGTCCT
AATAAGCGTTTAATGAAACATTGTGCAAACTGTCATTCATTCATTGACATCTGGGAATATCATC
AGCAGGCTAATGTCCTGCAGCTTTATGTTAACTAATCACATGTTCTGTGTGTTCTTACAACTAT
TAGAGTATCTGGCTCTTTCAGTCACTCAGCATTTGTTGACTGAATAAATGTTACGTGTTTTTCA
TTGTGAAAGACTCATTTTTACTGGATTGAACTGCAATTGAGAAGTCAAGCACCTTGGTAAAGAA
CAGAAGAGAGGTTCAGCATCTTATTATCTGAGGGATTGTGATTAGTTTTTTCTAGTAGGGAGGA
AAGGAGTGACCCTGTCCAAACCAGGGAAGGAGTCTCAGGAGAAATAGTATTGGTCTAATACCAG
AGGATGGGCATAATTATGATATTCCTTTTCAAAGCCTTCCATGGATCCTCCTCAAAGAACAAAG
AATATAATGGAGAGAATTCAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005319263	(Get FASTA)	NCBI Sequence Viewer
	XP_013211432	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000006585.3
	ENSSTOP00000027459.1
GenBank Protein	KAG3278160	(Get FASTA)	NCBI Sequence Viewer
	KAG3278161	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_013211432 ⟸ XM_013355978
- Peptide Label:	isoform X2
- UniProtKB:	I3M9L0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHY GKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIK IIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSSVLHEGEGNIRSVKWRGHLIAWANNMGV KIFDITSKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKICSVKERHASEMRDLPS RYVEIVSQFETEFHISGLAPLCDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLSETCEEISSD ALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEI SQRNIKRHKILDIGLAYINHLVERGEYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAVSPY LPRGDPVLKPLIYEMVLHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLK TLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNED KISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPL EKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSI DKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADS LSLLKKMHRTQMKGVLVDEENICESCLSPILPTELSYTILQHLQRKEPWTRKCNFGDEKIAQLC LSVSSCCSF hide sequence

RefSeq Acc Id:	XP_005319263 ⟸ XM_005319206
- Peptide Label:	isoform X1
- UniProtKB:	A0A287D1P4 (UniProtKB/TrEMBL), I3M9L0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHY GKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIK IIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSSVLHEGEGNIRSVKWRGHLIAWANNMGV KIFDITSKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKICSVKERHASEMRDLPS RYVEIVSQFETEFHISGLAPLCDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLSETCEEISSD ALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEI SQRNIKRHKILDIGLAYINHLVERGEYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAVSPY LPRGDPVLKPLIYEMVLHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLK TLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNED KISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPL EKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSI DKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADS LSLLKKMHRTQMKGVLVDEENICESCLSPILPTDAAKPFSVVVFHCRHMFHKECLPVPSMNSPT QYCNICSAKNRGPGSAILEMKK hide sequence

RefSeq Acc Id:

ENSSTOP00000027459 ⟸ ENSSTOT00000037628

RefSeq Acc Id:

ENSSTOP00000006585 ⟸ ENSSTOT00000007372

Protein Domains

RING-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000007343	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000007372.3	UniProtKB/TrEMBL
	ENSSTOT00000037628.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.10	UniProtKB/TrEMBL
	2.130.10.10	UniProtKB/TrEMBL
InterPro	Clathrin_H-chain/VPS_repeat	UniProtKB/TrEMBL
	TPR-like_helical_dom_sf	UniProtKB/TrEMBL
	VPS41	UniProtKB/TrEMBL
	Vps41/Vps8	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
NCBI Gene	Vps41	ENTREZGENE
PANTHER	PTHR12616	UniProtKB/TrEMBL
	VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG	UniProtKB/TrEMBL
Pfam	Clathrin	UniProtKB/TrEMBL
PIRSF	VPS41	UniProtKB/TrEMBL
PROSITE	CHCR	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
SMART	CLH	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
	SSF50978	UniProtKB/TrEMBL
UniProt	A0A287D1P4	ENTREZGENE, UniProtKB/TrEMBL
	I3M9L0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-01-29	Vps41	VPS41 subunit of HOPS complex		VPS41, HOPS complex subunit	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM