Setd2 (SET domain containing 2, histone lysine methyltransferase) - Rat Genome Database

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Gene: Setd2 (SET domain containing 2, histone lysine methyltransferase) Ictidomys tridecemlineatus
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Symbol: Setd2
Name: SET domain containing 2, histone lysine methyltransferase
RGD ID: 12507699
Description: ENCODES a protein that exhibits alpha-tubulin binding (ortholog); histone methyltransferase activity (H3-K36 specific) (ortholog); histone-lysine N-methyltransferase activity (ortholog); INVOLVED IN angiogenesis (ortholog); cell migration involved in vasculogenesis (ortholog); coronary vasculature morphogenesis (ortholog); PARTICIPATES IN histone modification pathway; renal cell carcinoma pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Agenesis of Corpus Callosum (ortholog); autistic disorder (ortholog); FOUND IN chromosome (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: histone-lysine N-methyltransferase SETD2; SET domain containing 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118201,246,801 - 201,349,701 (-)NCBI
SpeTri2.0NW_004936596795,940 - 898,823 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
chromosome  (ISO)
nucleus  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Setd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118201,246,801 - 201,349,701 (-)NCBI
SpeTri2.0NW_004936596795,940 - 898,823 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SETD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl347,016,429 - 47,164,113 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl347,016,429 - 47,163,967 (-)EnsemblGRCh38hg38GRCh38
GRCh38347,016,431 - 47,164,113 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37347,057,926 - 47,205,603 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36347,032,910 - 47,140,744 (-)NCBINCBI36hg18NCBI36
Celera346,996,415 - 47,143,855 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef347,101,003 - 47,248,517 (-)NCBIHuRef
CHM1_1347,008,283 - 47,155,743 (-)NCBICHM1_1
Setd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399110,361,368 - 110,447,701 (+)NCBIGRCm39mm39
GRCm39 Ensembl9110,361,665 - 110,447,701 (+)Ensembl
GRCm389110,532,500 - 110,618,633 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9110,532,597 - 110,618,633 (+)EnsemblGRCm38mm10GRCm38
MGSCv379110,435,101 - 110,521,137 (+)NCBIGRCm37mm9NCBIm37
MGSCv369110,393,444 - 110,463,449 (+)NCBImm8
Celera9110,275,024 - 110,348,565 (+)NCBICelera
Cytogenetic Map9F2NCBI
Setd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28110,511,808 - 110,597,489 (+)NCBI
Rnor_6.0 Ensembl8118,803,075 - 118,888,224 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08118,802,478 - 118,888,224 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08118,163,197 - 118,229,411 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48114,913,851 - 114,999,955 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18114,953,667 - 115,019,393 (+)NCBI
Celera8109,796,476 - 109,881,676 (+)NCBICelera
Cytogenetic Map8q32NCBI
Setd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542025,090,798 - 25,177,760 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542025,070,626 - 25,178,410 (+)NCBIChiLan1.0ChiLan1.0
SETD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1348,017,856 - 48,164,007 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl348,018,517 - 48,163,999 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0346,916,615 - 47,064,046 (-)NCBIMhudiblu_PPA_v0panPan3
SETD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12041,675,539 - 41,800,697 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2041,675,599 - 41,800,612 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2041,591,796 - 41,716,953 (+)NCBI
ROS_Cfam_1.02042,158,289 - 42,283,519 (+)NCBI
UMICH_Zoey_3.12041,400,062 - 41,525,212 (+)NCBI
UNSW_CanFamBas_1.02041,801,303 - 41,926,169 (+)NCBI
UU_Cfam_GSD_1.02042,081,936 - 42,207,122 (+)NCBI
SETD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,884,712 - 29,996,360 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,884,708 - 29,996,285 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21333,143,413 - 33,229,793 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SETD2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1228,421,178 - 8,567,221 (-)NCBI
ChlSab1.1 Ensembl228,420,960 - 8,567,201 (-)Ensembl
Setd2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473074,187,981 - 74,277,857 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013361835   ⟹   XP_013217289
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118201,246,801 - 201,349,698 (-)NCBI
SpeTri2.0NW_004936596795,940 - 898,823 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005735911
RefSeq Status:
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118201,248,015 - 201,349,701 (-)NCBI
Protein Sequences
Protein RefSeqs XP_013217289 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013217289   ⟸   XM_013361835
- Sequence:
Protein Domains
AWS   Post-SET   SET   WW


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000022116 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000016952 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000023923 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1740.100 UniProtKB/TrEMBL
  1.20.930.10 UniProtKB/TrEMBL
InterPro AWS_dom UniProtKB/TrEMBL
  Post-SET_dom UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SETD2 UniProtKB/TrEMBL
  SETD2/Set2_SET UniProtKB/TrEMBL
  SRI UniProtKB/TrEMBL
  SRI_sf UniProtKB/TrEMBL
  TFIIS/LEDGF_dom_sf UniProtKB/TrEMBL
  WW_dom UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
NCBI Gene Setd2 ENTREZGENE
PANTHER PTHR46711 UniProtKB/TrEMBL
Pfam AWS UniProtKB/TrEMBL
  PF00397 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
  SRI UniProtKB/TrEMBL
PROSITE AWS UniProtKB/TrEMBL
  POST_SET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
  WW_DOMAIN_1 UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
SMART AWS UniProtKB/TrEMBL
  PostSET UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
  SM00456 UniProtKB/TrEMBL
Superfamily-SCOP SSF51045 UniProtKB/TrEMBL
UniProt I3MXV7_ICTTR UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-01 Setd2  SET domain containing 2, histone lysine methyltransferase    SET domain containing 2  Symbol and/or name change 5135510 APPROVED