Myrip (myosin VIIA and Rab interacting protein) - Rat Genome Database

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Gene: Myrip (myosin VIIA and Rab interacting protein) Ictidomys tridecemlineatus
Analyze
Symbol: Myrip
Name: myosin VIIA and Rab interacting protein
RGD ID: 12506259
Description: ENCODES a protein that exhibits actin binding (inferred); myosin binding (inferred); protein kinase A binding (inferred); INVOLVED IN positive regulation of insulin secretion (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN apical plasma membrane (ortholog); dense core granule (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC101956703; myosin VIIA and Rab interacting protein, transcript variant X1; myosin VIIA and Rab interacting protein, transcript variant X2; myosin VIIA and Rab interacting protein, transcript variant X3; myosin VIIA and Rab interacting protein, transcript variant X4; rab effector MyRIP
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118195,783,381 - 196,114,170 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647328,982,604 - 29,252,745 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647328,921,837 - 29,252,737 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Myrip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118195,783,381 - 196,114,170 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647328,982,604 - 29,252,745 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647328,921,837 - 29,252,737 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYRIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38339,808,914 - 40,260,321 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl339,808,914 - 40,260,321 (+)EnsemblGRCh38hg38GRCh38
GRCh37339,850,405 - 40,301,812 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36339,826,307 - 40,276,816 (+)NCBINCBI36Build 36hg18NCBI36
Build 34339,826,306 - 40,276,808NCBI
Celera339,793,218 - 40,244,467 (+)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef339,894,694 - 40,345,886 (+)NCBIHuRef
CHM1_1339,802,159 - 40,251,713 (+)NCBICHM1_1
T2T-CHM13v2.0339,822,295 - 40,275,401 (+)NCBIT2T-CHM13v2.0
Myrip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399120,132,996 - 120,305,167 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9120,130,579 - 120,303,907 (+)EnsemblGRCm39 Ensembl
GRCm389120,303,520 - 120,476,101 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9120,301,513 - 120,474,841 (+)EnsemblGRCm38mm10GRCm38
MGSCv379120,213,191 - 120,383,952 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369120,152,771 - 120,323,532 (+)NCBIMGSCv36mm8
Celera9120,765,412 - 120,944,453 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map971.5NCBI
Myrip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88128,895,371 - 129,062,420 (+)NCBIGRCr8
mRatBN7.28120,017,749 - 120,184,821 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8120,017,524 - 120,183,833 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8125,626,718 - 125,759,584 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08123,825,741 - 123,958,593 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08121,667,882 - 121,800,814 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08128,972,307 - 129,139,257 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8128,972,311 - 129,139,251 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08128,171,783 - 128,337,841 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48125,317,671 - 125,478,667 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18125,337,407 - 125,492,971 (+)NCBI
Celera8119,163,194 - 119,324,938 (+)NCBICelera
Cytogenetic Map8q32NCBI
Myrip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542029,540,027 - 29,696,504 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542029,542,479 - 29,697,646 (-)NCBIChiLan1.0ChiLan1.0
MYRIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2239,771,353 - 40,219,420 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1339,776,213 - 40,224,181 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0339,715,890 - 40,163,826 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1339,991,586 - 40,435,763 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl340,079,777 - 40,433,613 (+)Ensemblpanpan1.1panPan2
MYRIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1239,448,564 - 9,765,328 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl239,448,559 - 9,763,182 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha239,425,279 - 9,798,884 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0239,674,928 - 10,051,701 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl239,674,852 - 10,051,368 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1239,487,819 - 9,861,978 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0239,629,847 - 9,999,590 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0239,625,718 - 9,987,209 (+)NCBIUU_Cfam_GSD_1.0
MYRIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1324,347,660 - 24,556,735 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11324,347,574 - 24,556,743 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21326,806,466 - 26,855,152 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYRIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1221,369,820 - 1,765,121 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl221,370,001 - 1,765,311 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041165,438,597 - 165,844,373 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myrip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473078,388,192 - 78,582,051 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000012160   ⟹   ENSSTOP00000010901
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493647328,982,604 - 29,252,745 (+)Ensembl
RefSeq Acc Id: XM_021732359   ⟹   XP_021588034
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118195,783,381 - 196,114,170 (+)NCBI
SpeTri2.0NW_00493647328,921,837 - 29,252,737 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732376   ⟹   XP_021588051
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118195,783,381 - 196,114,170 (+)NCBI
SpeTri2.0NW_00493647328,921,837 - 29,252,737 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732384   ⟹   XP_021588059
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118195,987,470 - 196,114,167 (+)NCBI
SpeTri2.0NW_00493647329,126,174 - 29,252,737 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040290040   ⟹   XP_040145974
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118195,844,065 - 196,114,170 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021588034   ⟸   XM_021732359
- Peptide Label: isoform X1
- UniProtKB: I3MIN5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021588051   ⟸   XM_021732376
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_021588059   ⟸   XM_021732384
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_040145974   ⟸   XM_040290040
- Peptide Label: isoform X3
RefSeq Acc Id: ENSSTOP00000010901   ⟸   ENSSTOT00000012160
Protein Domains
RabBD


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000012159 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000012160.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro FYVE_2 UniProtKB/TrEMBL
  Myrip/Melanophilin UniProtKB/TrEMBL
  Rab_BD UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene Myrip ENTREZGENE
PANTHER MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED UniProtKB/TrEMBL
  RAB EFFECTOR MYRIP UniProtKB/TrEMBL
Pfam FYVE_2 UniProtKB/TrEMBL
  Rab_eff_C UniProtKB/TrEMBL
PROSITE RABBD UniProtKB/TrEMBL
Superfamily-SCOP SSF57903 UniProtKB/TrEMBL
UniProt I3MIN5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-09 Myrip  myosin VIIA and Rab interacting protein  LOC101956703  myosin VIIA and Rab interacting protein  Symbol and/or name change 5135510 APPROVED
2021-03-26 LOC101956703  myosin VIIA and Rab interacting protein  Myrip  myosin VIIA and Rab interacting protein  Symbol and/or name change 5135510 APPROVED