Arf1 (ADP ribosylation factor 1) - Rat Genome Database

Name: Arf1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Arf1 (ADP ribosylation factor 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Arf1

Name:

ADP ribosylation factor 1

RGD ID:

12502598

Description:

ENCODES a protein that exhibits GDP binding (ortholog); GTP binding (ortholog); magnesium ion binding (ortholog); INVOLVED IN actin filament organization (ortholog); dendritic spine organization (ortholog); Golgi to transport vesicle transport (ortholog); PARTICIPATES IN Arf family mediated signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH acute pancreatitis (ortholog); Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN cell leading edge (ortholog); COPI-coated vesicle (ortholog); cytosol (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ADP-ribosylation factor 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	87,776,242 - 87,778,336 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936864	117,510 - 119,612 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute pancreatitis (ISO)

Breast Neoplasms (ISO)

Charcot-Marie-Tooth disease (ISO)

gastrointestinal stromal tumor (ISO)

multiple mitochondrial dysfunctions syndrome 3 (ISO)

Neoplasm Invasiveness (ISO)

parathyroid carcinoma (ISO)

Periventricular Nodular Heterotopia 8 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin filament organization (ISO)

dendritic spine organization (ISO)

Golgi to transport vesicle transport (ISO)

intracellular copper ion homeostasis (ISO)

long-term synaptic depression (ISO)

lysosomal membrane organization (ISO)

mitotic cleavage furrow ingression (ISO)

positive regulation of calcium ion-dependent exocytosis (ISO)

positive regulation of dendritic spine development (ISO)

positive regulation of endocytosis (ISO)

positive regulation of ER to Golgi vesicle-mediated transport (ISO)

positive regulation of late endosome to lysosome transport (ISO)

positive regulation of protein secretion (ISO)

positive regulation of sodium ion transmembrane transport (ISO)

postsynaptic actin cytoskeleton organization (ISO)

protein transport (IEA)

regulation of Arp2/3 complex-mediated actin nucleation (ISO)

regulation of phospholipid metabolic process (ISO)

regulation of receptor internalization (ISO)

synaptic vesicle budding (ISO)

very-low-density lipoprotein particle assembly (ISO)

vesicle-mediated transport (IEA,ISO)

Cellular Component

cell leading edge (ISO)

COPI-coated vesicle (ISO)

cytosol (ISO)

endomembrane system (ISO)

glutamatergic synapse (ISO)

Golgi apparatus (IEA)

Golgi membrane (ISO)

late endosome (ISO)

peroxisomal membrane (ISO)

postsynaptic density (ISO)

protein-containing complex (ISO)

sarcomere (ISO)

trans-Golgi network (ISO)

Molecular Function

GDP binding (ISO)

GTP binding (IEA,ISO)

GTPase activity (IEA)

magnesium ion binding (ISO)

nucleotide binding (IEA)

phospholipase D activator activity (ISO)

protein binding (ISO)

protein domain specific binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

Arf family mediated signaling pathway (ISO)

phosphatidylinositol 3-kinase class I signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (ISO)

References

Genomics

Comparative Map Data

Arf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	87,776,242 - 87,778,336 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936864	117,510 - 119,612 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARF1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	228,082,708 - 228,099,212 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	228,082,708 - 228,099,212 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	228,270,409 - 228,286,913 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	226,336,984 - 226,353,536 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	224,577,163 - 224,593,645	NCBI
Celera	1	201,460,593 - 201,477,145 (+)	NCBI		Celera
Cytogenetic Map	1	q42.13	NCBI
HuRef	1	198,785,590 - 198,802,034 (+)	NCBI		HuRef
CHM1_1	1	229,542,706 - 229,559,258 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	227,271,693 - 227,288,198 (+)	NCBI		T2T-CHM13v2.0

Arf1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	59,102,237 - 59,119,042 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	59,102,238 - 59,119,096 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	59,211,412 - 59,228,267 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	59,211,412 - 59,228,270 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	59,024,914 - 59,041,769 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	59,027,608 - 59,044,381 (-)	NCBI		MGSCv36	mm8
Celera	11	63,976,432 - 63,993,249 (-)	NCBI		Celera
Cytogenetic Map	11	B1.3	NCBI
cM Map	11	37.05	NCBI

Arf1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	43,997,983 - 44,014,461 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	43,997,986 - 44,014,434 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	48,692,668 - 48,708,202 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	48,183,026 - 48,198,560 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	43,686,624 - 43,702,158 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	45,562,700 - 45,579,214 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	45,563,547 - 45,579,029 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	45,318,170 - 45,334,673 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	45,516,609 - 45,532,091 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	45,529,387 - 45,545,841 (-)	NCBI
Celera	10	43,262,080 - 43,277,562 (-)	NCBI		Celera
Cytogenetic Map	10	q22	NCBI

Arf1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955581	319,942 - 335,112 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955581	319,942 - 335,112 (-)	NCBI	ChiLan1.0	ChiLan1.0

ARF1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	1	21,445,519 - 21,462,037 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	203,484,803 - 203,501,395 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	208,695,615 - 208,712,105 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	208,695,615 - 208,712,105 (+)	Ensembl	panpan1.1		panPan2

ARF1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	835,476 - 836,424 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	835,476 - 836,424 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	315,387 - 316,334 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	554,686 - 568,903 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	554,687 - 568,881 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	746,548 - 747,495 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	527,341 - 528,288 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	513,272 - 514,220 (-)	NCBI		UU_Cfam_GSD_1.0

ARF1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	51,219,667 - 51,237,639 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	51,219,597 - 51,237,640 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	53,874,559 - 53,892,570 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ARF1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	1,628,836 - 1,644,502 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	1,628,751 - 1,644,499 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	1,510,307 - 1,525,996 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Arf1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624937	857,795 - 871,089 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005341279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005341279 ⟹ XP_005341336

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	87,776,242 - 87,778,336 (-)	NCBI
SpeTri2.0	NW_004936864	117,510 - 119,612 (-)	NCBI

Sequence:

show sequence

GTCTCTGGCCAGTGTCGCTTCCAACCACCCACAAGGATGGGGAATATCTTTGCAAACCTCTTCA
AGGGCCTTTTTGGCAAAAAAGAAATGCGCATCCTCATGGTGGGCCTGGATGCTGCAGGGAAGAC
GACGATTCTCTACAAACTGAAGCTGGGTGAAATTGTGACCACTATTCCTACCATAGGTTTTAAT
GTGGAAACCGTTGAGTACAAGAATATCAGCTTCACTGTGTGGGATGTGGGTGGCCAAGACAAGA
TCCGGCCACTATGGCGCCACTACTTCCAGAACACCCAAGGCTTGATCTTTGTGGTGGACAGCAA
TGACAGAGAGCGTGTGAATGAGGCCCGCGAGGAGCTCATGAGGATGCTGGCTGAGGATGAGCTG
CGGGACGCTGTCCTCCTGGTGTTTGCCAACAAGCAGGACCTCCCAAATGCCATGAACGCAGCCG
AAATCACAGACAAGCTGGGGCTGCACTCGCTACGTCACAGGAACTGGTACATTCAGGCCACCTG
TGCCACCAGCGGGGACGGGCTCTATGAAGGACTGGACTGGCTGTCCAATCAGCTCCGGAACCAG
AAGTGAACCTGAACCCCCCCACCCCCTCACTTTCTCCTCTCTGCCCTCGCTTTCCTCTCATGTG
GCAAACGTGCGACTCTGTGGTCCTGAGTGCCAGAAGCTGTCTCCATGGGTTGGTCAGTGTGCAT
CGCACCGTGCTGTACATGTGCAGACGCAGCCTGCAGCCAGGTTTTTATTTAATGTAAATAGTTT
CTGTTTCCACTGAGGCAGTTTCTGGTACTCCTATGCAATATTACTCAGCTTTTTTATTGTAAAA
AGAGAATCAACTCACTGTCAGTACTGAGGAGGGATTTAGGCTTGTGGGCACCTGGCCTCCAGGA
GCTCCTGGGCGGTAGATTGGTGTTGGGATCCATTTGGTGGTTGGTTTTTAACCCAAACTCAGTG
CATTTTTTAAAATAGTTAAAAATACAAGATAAGGAGAACACTTGAACACACAGAAGGGAGACTA
TGCCTAGTGTACAGCCTGAATGCTAGTCCATCGGATCAGCTGTTCCCCTGTGGGAACACAAAGA
CGGTGACACAAACCGCCATCCACTGCATGGTCCCAGTAGAGACCCCGTGACTCGCCTGTCTTTG
GGTCACTTGCATTCCATAGCGTTGTGCTTGTACTTGTGCTCACACAGTCACCTGGGGGCGGGCT
GGGAGAGCCATTGCAGGGGACACGGCCCAGATGCGCCCTTTGTTGGCGTGTGGCCAGAGCAGTA
GCCCATGTTCCCAGCACCCACTCACTCTTGCACCTGCTCAGCCCGCTGGCAGGAGGTCTGGGTC
TCACCAGCATGAGTGCGTGCAAGCTGGGAGGGTTGGTCCACTCCAGACCCACAGGTCCCGGAGC
ACCCCCATCTCCATGTGTGAAGTAGCTTCCTCCCTCAGCCTGCAAGGGTCCGATTTGCCATCGA
AAAAGACGACCTCTACTTTTTTCTTTTGTATTTTGATAAACACTGAAGAAGCTGGAGCTGTTAA
ATTTATCTTGGGGAAACCTCAGAACTGGTTTATTTGGTGTCGTGGAACCTCTTAATGCTTTCAA
TACACGATTAGTAATCAACTGTTTTGTATACTTGTTTTCAGTTTTCATTTCGACAAGCACTGTA
ATTATAGCTATTAGAATAAAGTCTCTTAACTATTTCACGGGC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005341336	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000008326.2
	ENSSTOP00000030744.1

RefSeq Acc Id:	XP_005341336 ⟸ XM_005341279
- UniProtKB:	I3MD93 (UniProtKB/TrEMBL), A0A287DB38 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFT VWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQ DLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQK hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000009288	UniProtKB/TrEMBL
	ENSSTOG00000025407	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000009280.3	UniProtKB/TrEMBL
	ENSSTOT00000027744.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	Arf1_5_like	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	Small_GTP-bd_dom	UniProtKB/TrEMBL
	Small_GTPase_ARF	UniProtKB/TrEMBL
	Small_GTPase_ARF/SAR	UniProtKB/TrEMBL
NCBI Gene	Arf1	ENTREZGENE
PANTHER	ADP-RIBOSYLATION FACTOR 1	UniProtKB/TrEMBL
	PTHR11711	UniProtKB/TrEMBL
Pfam	Arf	UniProtKB/TrEMBL
PRINTS	SAR1GTPBP	UniProtKB/TrEMBL
PROSITE	ARF	UniProtKB/TrEMBL
SMART	ARF	UniProtKB/TrEMBL
	RAB	UniProtKB/TrEMBL
	SAR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	A0A287DB38	ENTREZGENE, UniProtKB/TrEMBL
	I3MD93	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Imported Annotations - PID (archival)