Fscn1 (fascin actin-bundling protein 1) - Rat Genome Database
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Gene: Fscn1 (fascin actin-bundling protein 1) Ictidomys tridecemlineatus
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Symbol: Fscn1
Name: fascin actin-bundling protein 1
RGD ID: 12502567
Description: ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); drug binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament bundle assembly (ortholog); cell migration (ortholog); PARTICIPATES IN protein kinase C (PKC) signaling pathway; ASSOCIATED WITH Bile Duct Neoplasms (ortholog); cholangiocarcinoma (ortholog); common bile duct neoplasm (ortholog); FOUND IN actin cytoskeleton (ortholog); cell projection membrane (ortholog); cell-cell junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: fascin; fascin homolog 1, actin-bundling protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936765609,894 - 619,417 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Fscn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936765609,894 - 619,417 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FSCN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl75,592,816 - 5,606,655 (+)EnsemblGRCh38hg38GRCh38
GRCh3875,592,816 - 5,606,655 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3775,632,436 - 5,646,287 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh3775,632,447 - 5,646,286 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3675,598,980 - 5,612,812 (+)NCBINCBI36hg18NCBI36
Build 3475,405,694 - 5,419,526NCBI
Celera75,592,071 - 5,605,904 (+)NCBI
Cytogenetic Map7p22.1NCBI
HuRef75,544,716 - 5,558,303 (+)NCBIHuRef
CHM1_175,632,035 - 5,645,887 (+)NCBICHM1_1
CRA_TCAGchr7v275,678,781 - 5,692,632 (+)NCBI
Fscn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395142,946,110 - 142,958,944 (+)NCBIGRCm39mm39
GRCm385142,960,355 - 142,973,189 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5142,960,343 - 142,973,185 (+)EnsemblGRCm38mm10GRCm38
MGSCv375143,722,034 - 143,734,868 (+)NCBIGRCm37mm9NCBIm37
MGSCv365143,225,511 - 143,238,323 (+)NCBImm8
Celera5140,008,743 - 140,021,597 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map581.84NCBI
Fscn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21211,597,042 - 11,610,183 (-)NCBI
Rnor_6.0 Ensembl1213,656,554 - 13,668,515 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01213,655,459 - 13,668,595 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01215,688,989 - 15,702,125 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1213,390,657 - 13,403,285 (-)NCBICelera
Cytogenetic Map12p11NCBI
Fscn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546010,402,855 - 10,412,710 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546010,402,855 - 10,412,459 (+)NCBIChiLan1.0ChiLan1.0
FSCN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.175,865,307 - 5,877,366 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v075,848,902 - 5,862,756 (+)NCBIMhudiblu_PPA_v0panPan3
FSCN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl612,354,599 - 12,370,808 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1612,360,849 - 12,370,906 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
FSCN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl34,134,170 - 4,145,394 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.134,134,173 - 4,143,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.234,776,501 - 4,785,603 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FSCN1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12816,127,033 - 16,142,285 (-)NCBI
ChlSab1.1 Ensembl2816,127,015 - 16,142,337 (-)Ensembl
Fscn1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474028,038,216 - 28,047,252 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005340037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGTP01104617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005340037   ⟹   XP_005340094
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_004936765609,894 - 619,417 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005340094 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005340094   ⟸   XM_005340037
- UniProtKB: I3NBV1 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Fascin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020923 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000021848 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000029421 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000029770 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOT00000030193 UniProtKB/TrEMBL
InterPro Actin-crosslinking UniProtKB/TrEMBL
  Fascin UniProtKB/TrEMBL
  Fascin-domain UniProtKB/TrEMBL
  Fascin_metazoans UniProtKB/TrEMBL
  FSCN1 UniProtKB/TrEMBL
NCBI Gene Fscn1 ENTREZGENE
PANTHER PTHR10551 UniProtKB/TrEMBL
  PTHR10551:SF23 UniProtKB/TrEMBL
Pfam Fascin UniProtKB/TrEMBL
PIRSF Fascin UniProtKB/TrEMBL
Superfamily-SCOP SSF50405 UniProtKB/TrEMBL
UniProt A0A287D7D2_ICTTR UniProtKB/TrEMBL
  I3NBV1 ENTREZGENE, UniProtKB/TrEMBL