Inhba (inhibin subunit beta A) - Rat Genome Database

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Gene: Inhba (inhibin subunit beta A) Ictidomys tridecemlineatus
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Symbol: Inhba
Name: inhibin subunit beta A
RGD ID: 12494455
Description: ENCODES a protein that exhibits cytokine activity (ortholog); identical protein binding (ortholog); peptide hormone binding (ortholog); INVOLVED IN activin receptor signaling pathway (ortholog); cardiac fibroblast cell development (ortholog); cellular response to angiotensin (ortholog); ASSOCIATED WITH Acute Liver Failure (ortholog); Endometrioid Carcinomas (ortholog); gestational diabetes (ortholog); FOUND IN activin A complex (ortholog); extracellular space (ortholog); inhibin A complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inhibin beta A chain; inhibin beta A subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511897,666,669 - 97,672,334 (-)NCBI
SpeTri2.0NW_00493647816,878,725 - 16,884,065 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activin receptor signaling pathway  (ISO)
cardiac fibroblast cell development  (ISO)
cellular response to angiotensin  (ISO)
cellular response to cholesterol  (ISO)
cellular response to follicle-stimulating hormone stimulus  (ISO)
endodermal cell differentiation  (ISO)
extrinsic apoptotic signaling pathway  (ISO)
eyelid development in camera-type eye  (ISO)
GABAergic neuron differentiation  (ISO)
hair follicle development  (ISO)
hematopoietic progenitor cell differentiation  (ISO)
hemoglobin biosynthetic process  (ISO)
male gonad development  (ISO)
mesoderm formation  (ISO)
mesodermal cell differentiation  (ISO)
multicellular organism aging  (ISO)
negative regulation of cell growth  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of G1/S transition of mitotic cell cycle  (ISO)
negative regulation of hair follicle development  (ISO)
odontogenesis  (ISO)
ovarian follicle development  (ISO)
positive regulation of collagen biosynthetic process  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of erythrocyte differentiation  (ISO)
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of ovulation  (ISO)
positive regulation of pathway-restricted SMAD protein phosphorylation  (ISO)
positive regulation of protein metabolic process  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription by RNA polymerase III  (ISO)
progesterone secretion  (ISO)
regulation of follicle-stimulating hormone secretion  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
response to xenobiotic stimulus  (ISO)
roof of mouth development  (ISO)
signal transduction  (IEA)
striatal medium spiny neuron differentiation  (ISO)
transcription by RNA polymerase II  (ISO)

Cellular Component

References

Genomics

Comparative Map Data
Inhba
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511897,666,669 - 97,672,334 (-)NCBI
SpeTri2.0NW_00493647816,878,725 - 16,884,065 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INHBA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38741,685,114 - 41,705,406 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl741,667,168 - 41,705,834 (-)EnsemblGRCh38hg38GRCh38
GRCh37741,724,712 - 41,742,688 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36741,695,126 - 41,709,231 (-)NCBINCBI36hg18NCBI36
Build 34741,502,035 - 41,513,299NCBI
Celera741,719,390 - 41,733,490 (-)NCBI
Cytogenetic Map7p14.1NCBI
HuRef741,613,504 - 41,627,622 (-)NCBIHuRef
CHM1_1741,731,917 - 41,746,019 (-)NCBICHM1_1
T2T-CHM13v2.0741,843,512 - 41,861,485 (-)NCBI
CRA_TCAGchr7v2741,768,467 - 41,782,571 (-)NCBI
Inhba
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391316,178,841 - 16,206,194 (+)NCBIGRCm39mm39
GRCm39 Ensembl1316,186,436 - 16,206,206 (+)Ensembl
GRCm381316,004,256 - 16,031,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1316,011,851 - 16,031,621 (+)EnsemblGRCm38mm10GRCm38
MGSCv371316,106,308 - 16,119,044 (+)NCBIGRCm37mm9NCBIm37
MGSCv361315,805,362 - 15,818,098 (+)NCBImm8
Celera1316,301,736 - 16,314,777 (+)NCBICelera
Cytogenetic Map13A1NCBI
cM Map135.85NCBI
Inhba
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21749,091,635 - 49,111,573 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1749,095,920 - 49,108,982 (-)Ensembl
Rnor_6.01751,894,869 - 51,919,998 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1751,898,217 - 51,912,496 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01749,961,222 - 49,985,653 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41757,244,466 - 57,257,531 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11757,247,306 - 57,260,372 (-)NCBI
Celera1745,163,387 - 45,176,397 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
Inhba
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554602,046,588 - 2,066,609 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554602,054,879 - 2,066,628 (+)NCBIChiLan1.0ChiLan1.0
INHBA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1742,580,730 - 42,598,712 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl742,580,730 - 42,595,097 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0742,538,591 - 42,556,578 (+)NCBIMhudiblu_PPA_v0panPan3
INHBA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1188,272,978 - 8,288,432 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl188,272,872 - 8,283,794 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha188,122,697 - 8,138,128 (+)NCBI
ROS_Cfam_1.0188,321,520 - 8,336,958 (+)NCBI
ROS_Cfam_1.0 Ensembl188,318,003 - 8,332,480 (+)Ensembl
UMICH_Zoey_3.1188,301,757 - 8,317,182 (+)NCBI
UNSW_CanFamBas_1.0188,269,907 - 8,285,348 (+)NCBI
UU_Cfam_GSD_1.0188,385,256 - 8,400,687 (+)NCBI
INHBA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1852,889,684 - 52,900,967 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,115,379 - 53,117,128 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11852,889,684 - 52,909,260 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21857,997,858 - 58,017,387 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21255,481,493 - 55,483,255 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap18q24NCBI
INHBA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12116,936,054 - 16,951,430 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2116,936,175 - 16,946,880 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660625,522,195 - 5,540,211 (-)NCBIVero_WHO_p1.0
Inhba
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474019,464,289 - 19,482,888 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474019,458,835 - 19,482,570 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005319214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005319214   ⟹   XP_005319271
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440511897,666,669 - 97,672,334 (-)NCBI
SpeTri2.0NW_00493647816,878,725 - 16,884,065 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005319271 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3278174 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005319271   ⟸   XM_005319214
- UniProtKB: A0A287D8G8 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
TGF_BETA_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000034121 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000029829 ENTREZGENE
  ENSSTOP00000029829.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000036148.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  TGF-b_C UniProtKB/TrEMBL
  TGF-beta-rel UniProtKB/TrEMBL
  TGFb_CS UniProtKB/TrEMBL
NCBI Gene Inhba ENTREZGENE
PANTHER PTHR11848 UniProtKB/TrEMBL
Pfam TGF_beta UniProtKB/TrEMBL
PROSITE TGF_BETA_1 UniProtKB/TrEMBL
  TGF_BETA_2 UniProtKB/TrEMBL
SMART TGFB UniProtKB/TrEMBL
Superfamily-SCOP SSF57501 UniProtKB/TrEMBL
UniProt A0A287D8G8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-01 Inhba  inhibin subunit beta A    inhibin beta A subunit  Symbol and/or name change 5135510 APPROVED