Zc3hc1 (zinc finger C3HC-type containing 1)

Gene: Zc3hc1 (zinc finger C3HC-type containing 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Zc3hc1

Name:

zinc finger C3HC-type containing 1

RGD ID:

12494129

Description:

ENCODES a protein that exhibits protein kinase binding (ortholog); INVOLVED IN negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (ortholog); ASSOCIATED WITH coronary artery disease (ortholog); Coronary Disease (ortholog); genetic disease (ortholog); FOUND IN nuclear membrane (ortholog); nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

nuclear-interacting partner of ALK

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	25,031,165 - 25,056,533 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936579	5,163,771 - 5,189,130 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

coronary artery disease (ISO)

Coronary Disease (ISO)

genetic disease (ISO)

pleomorphic xanthoastrocytoma (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (ISO)

Cellular Component

nuclear membrane (ISO)

nucleoplasm (ISO)

nucleus (IEA)

Molecular Function

protein binding (ISO)

protein kinase binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Zc3hc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	25,031,165 - 25,056,533 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936579	5,163,771 - 5,189,130 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZC3HC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	130,018,286 - 130,051,451 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	130,018,287 - 130,051,451 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	129,658,126 - 129,691,291 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	129,445,362 - 129,478,469 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	129,252,083 - 129,285,165	NCBI
Celera	7	124,453,864 - 124,486,984 (-)	NCBI		Celera
Cytogenetic Map	7	q32.2	NCBI
HuRef	7	124,019,510 - 124,053,569 (-)	NCBI		HuRef
CHM1_1	7	129,591,677 - 129,624,778 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	131,331,648 - 131,364,836 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	129,042,758 - 129,076,662 (-)	NCBI

Zc3hc1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	30,366,383 - 30,391,019 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	30,366,379 - 30,391,027 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	30,366,384 - 30,391,049 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	30,366,380 - 30,391,028 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	30,316,388 - 30,341,010 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	30,316,398 - 30,341,020 (-)	NCBI		MGSCv36	mm8
Celera	6	30,376,373 - 30,400,991 (-)	NCBI		Celera
Cytogenetic Map	6	A3.3	NCBI
cM Map	6	12.52	NCBI

Zc3hc1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	59,957,402 - 59,979,336 (-)	NCBI		GRCr8
mRatBN7.2	4	58,989,989 - 59,011,925 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	58,989,987 - 59,011,933 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	63,968,069 - 63,989,945 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	59,884,248 - 59,906,124 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	58,286,162 - 58,308,039 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	57,684,678 - 57,706,613 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	57,684,678 - 57,706,613 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	57,445,868 - 57,468,238 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	57,280,829 - 57,302,839 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	54,089,110 - 54,111,129 (-)	NCBI		Celera
Cytogenetic Map	4	q22	NCBI

Zc3hc1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955479	10,692,738 - 10,717,228 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955479	10,692,438 - 10,717,368 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZC3HC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	166,838,557 - 166,873,418 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	18,848,802 - 18,883,663 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	121,983,549 - 122,018,106 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	134,502,334 - 134,536,401 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	134,502,334 - 134,536,401 (-)	Ensembl	panpan1.1		panPan2

ZC3HC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	6,831,017 - 6,852,852 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	6,514,731 - 6,536,790 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	6,591,330 - 6,613,580 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	6,591,783 - 6,613,577 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	6,796,495 - 6,819,419 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	6,539,839 - 6,562,164 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	6,684,657 - 6,706,699 (+)	NCBI		UU_Cfam_GSD_1.0

ZC3HC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	18,740,845 - 18,761,718 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	18,740,817 - 18,761,515 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	19,802,362 - 19,814,907 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZC3HC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	98,646,115 - 98,680,650 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666042	4,721,482 - 4,756,137 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Zc3hc1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624783	6,218,209 - 6,243,694 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624783	6,218,172 - 6,243,694 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021730407	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021730407 ⟹ XP_021586082

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	25,031,165 - 25,056,533 (+)	NCBI
SpeTri2.0	NW_004936579	5,163,771 - 5,189,130 (+)	NCBI

Sequence:

show sequence

ACCCGCGGGGAAGCAACTTTGCAACGGACCAACATGGCGGCGTCCAGTGAGGAGCAGGCGTTTG
CTTCAGGGGTTGAAAAAAACTGGGGTACAGTAGTCCGTTCCCCAGAGGGGACCCCTCAGAAAGT
CCGGCAGCTGATAGATGAGGGGATTGCCCCAGAAGAGGGAAGCGCAGAAGCGAGGGATACATCT
GCCACATTCCAGTCAGTTAATGGATCACCCCAAGCAGAACAACTTCCATTGGAATCTACAAGCA
AAGAAGCCTTCTTTAGCAGAGTAGAAACATTTTCTATATCCTTTTTCAGTACATGTAAGTTGTG
CTTTCTACCTGTTCCTGAAATTTTTATTCCTTCAGGCCATTACATCACTTACTCTGATATTTTA
ACTTGGTACCTGGAACTCAACTTACACAAAGTTGAACTCTTCTCATATATCCAAAGCTTTGCCC
AGCTCATGCTAGAGTTCAAGCCTAGGGTCTCACTCATGCTAGATCGATTTGGGATGTTACCATT
AGATGAGCCTGCTGTTCTTATTAGTGAATTCCTAGATCGTTTTCAAAACCTTTGTCACTTGGAC
CTCCAGCTTCCTTCCCTGAGGCCAGAGGACTTGAAAACTATGTGCTTGACAGAAGACAAGATCA
GTCTTCTGTTACACCTGCTTGAAGATGAACTTGATCACCGAACTGAAGAGAGAAAAACTCCAAG
CAAGTTAGGCTCCGACATCCAAGTCCACATCACTGCTTGTGTTCTCTCTCTGTGTGGCTGGGCA
TGTAGTTCTGCTTTGGAACCCATGCAGCTCTCCCTGATAACATGTTCACAGTGTATGAGGAAGG
TGGGGCTCTGGGGCTTCCAGCAGATCGAATCATCCATGACTGACCTGGATACATCCTTTGGCCT
GACCAACTCTCCAGTCCCAGGCCCTGAAGGTCGTCCAGAGCGCTTCCCTCTGGTGCCTGAATCG
CCTCGGAGGATGATGACCAGGAGCCAGGATGCCACATTTTCCCCAGGCTCAGAGCAGGTTGAAA
AGAGCCCTAGTCCCATTGTCTCCCAAACCCGGAGCTGGGATTCTTCTAGTCCTGTTGATCGGCC
TGAGCCGGAGGCAGCCAGCCCCACCACCAGAACCCAGCCAGTGACTCGAAGCATGGGAACAGGA
GACTCTGCTGGCCTGGAAGTACCCTCCAGTCCCCTCCGGAAAGCCAAACGAGCTCGCCTCTGCT
CTTCCAGTAGCTCAGACACATCTTCCCGGAGCTTCTTTGATCCCACCTCTCAGCACAGAGACTG
GTGCCCTTGGGTGAATATCACACTAGGCAAAGAATCTAGGGAGAATGATGGAACAGAGCTTGAT
GCCAGCACCCCAGCAGAGCCGGGCTGGAAGACAGTGCTGACCATCCTGTTGGCCCACAAACAGT
CTAATCAGCCAGCTGAAACAGACTCCATGAATCTCTCTGAAAAATCAAGAAAAGTATTCCGAAT
ATTCCGACAGTGGGAATCTTTATGCTCATCCTGAAGCTACTCTACCCTGTTCCTGGAGAAAACT
GAAATGAGAGTGACTTTTTGAAAAATAAAACCTGAATTTTCTTTGGGTCAGCTGATACTGTTTT
TCTCCATTCTGGTTTAATCATAAAGAGCCCCTGCCATTGCAGAGGTAGTGAGCGTCAACAATCT
GCATGTTTAACAGGAGACCCATTTCCCTGTGGGGATGTGGACAGGATGAGCAAACCCAGTTCTA
TTAAAGGACTGTGAGGCTACAAAACTAGATGGAAGACCCAGGAACATGCATTTCAGCAGCTTTA
GTGTGGGCAGTGTTTCAAGGACTGTATATCCCAGGATTTGACAGTGTGTGTTATTAAAGTATTT
GCCAAGATG

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Protein Sequences


Protein RefSeqs	XP_021586082	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000013783.3
GenBank Protein	KAG3277490	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021586082 ⟸ XM_021730407

- UniProtKB:

I3MPN3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAASSEEQAFASGVEKNWGTVVRSPEGTPQKVRQLIDEGIAPEEGSAEARDTSATFQSVNGSPQ
AEQLPLESTSKEAFFSRVETFSISFFSTCKLCFLPVPEIFIPSGHYITYSDILTWYLELNLHKV
ELFSYIQSFAQLMLEFKPRVSLMLDRFGMLPLDEPAVLISEFLDRFQNLCHLDLQLPSLRPEDL
KTMCLTEDKISLLLHLLEDELDHRTEERKTPSKLGSDIQVHITACVLSLCGWACSSALEPMQLS
LITCSQCMRKVGLWGFQQIESSMTDLDTSFGLTNSPVPGPEGRPERFPLVPESPRRMMTRSQDA
TFSPGSEQVEKSPSPIVSQTRSWDSSSPVDRPEPEAASPTTRTQPVTRSMGTGDSAGLEVPSSP
LRKAKRARLCSSSSSDTSSRSFFDPTSQHRDWCPWVNITLGKESRENDGTELDASTPAEPGWKT
VLTILLAHKQSNQPAETDSMNLSEKSRKVFRIFRQWESLCSS

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Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000015389	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000015390.3	UniProtKB/TrEMBL
NCBI Gene	Zc3hc1	ENTREZGENE
PANTHER	NUCLEAR-INTERACTING PARTNER OF ALK	UniProtKB/TrEMBL
	NUCLEAR-INTERACTING PARTNER OF ALK	UniProtKB/TrEMBL
UniProt	I3MPN3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD