Kcne4 (potassium voltage-gated channel subfamily E regulatory subunit 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Kcne4 (potassium voltage-gated channel subfamily E regulatory subunit 4) Ictidomys tridecemlineatus
Analyze
Symbol: Kcne4
Name: potassium voltage-gated channel subfamily E regulatory subunit 4
RGD ID: 12492259
Description: ENCODES a protein that exhibits potassium channel inhibitor activity (ortholog); INVOLVED IN membrane repolarization during action potential (inferred); membrane repolarization during ventricular cardiac muscle cell action potential (inferred); monoatomic ion transport (inferred); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel subfamily E member 4; potassium voltage-gated channel, Isk-related family, member 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303178,596,335 - 178,599,723 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365694,939,511 - 4,942,038 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365694,939,477 - 4,942,096 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcne4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303178,596,335 - 178,599,723 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365694,939,511 - 4,942,038 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365694,939,477 - 4,942,096 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNE4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,052,190 - 223,055,637 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,052,190 - 223,198,399 (+)EnsemblGRCh38hg38GRCh38
GRCh372223,916,908 - 223,920,355 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,625,106 - 223,628,599 (+)NCBINCBI36Build 36hg18NCBI36
Build 342223,742,431 - 223,744,133NCBI
Celera2217,682,314 - 217,685,808 (+)NCBICelera
Cytogenetic Map2q36.1NCBI
HuRef2215,768,183 - 215,771,892 (+)NCBIHuRef
CHM1_12223,923,002 - 223,926,710 (+)NCBICHM1_1
T2T-CHM13v2.02223,535,022 - 223,538,472 (+)NCBIT2T-CHM13v2.0
Kcne4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,794,628 - 78,797,749 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,794,475 - 78,797,745 (+)EnsemblGRCm39 Ensembl
GRCm38178,816,911 - 78,820,032 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,816,758 - 78,820,028 (+)EnsemblGRCm38mm10GRCm38
MGSCv37178,813,524 - 78,816,600 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36178,695,973 - 78,699,049 (+)NCBIMGSCv36mm8
MGSCv36179,687,642 - 79,690,718 (+)NCBIMGSCv36mm8
Cytogenetic Map1C4NCBI
cM Map140.89NCBI
Kcne4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8987,674,264 - 87,699,088 (+)NCBIGRCr8
mRatBN7.2980,243,429 - 80,251,533 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl980,247,379 - 80,250,979 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx988,677,383 - 88,678,571 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0993,792,619 - 93,793,807 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0992,188,829 - 92,190,017 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0984,688,873 - 84,693,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl984,689,150 - 84,690,338 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0984,440,098 - 84,448,108 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4978,200,904 - 78,202,092 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1978,384,322 - 78,385,511 (+)NCBI
Celera977,752,308 - 77,753,496 (+)NCBICelera
Cytogenetic Map9q34NCBI
Kcne4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545310,822,977 - 10,826,191 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545310,822,977 - 10,826,191 (-)NCBIChiLan1.0ChiLan1.0
KCNE4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213125,664,293 - 125,668,275 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B125,679,381 - 125,683,243 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B110,291,194 - 110,294,996 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B228,869,393 - 228,873,101 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B228,869,393 - 228,873,101 (+)Ensemblpanpan1.1panPan2
KCNE4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13728,994,797 - 28,998,596 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3728,996,105 - 28,996,990 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3729,831,026 - 29,834,649 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03729,020,674 - 29,024,293 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13728,930,228 - 28,933,850 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03728,864,748 - 28,868,366 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03728,875,316 - 28,878,940 (+)NCBIUU_Cfam_GSD_1.0
KCNE4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15124,912,406 - 124,915,780 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115124,910,708 - 124,915,787 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215138,615,216 - 138,619,085 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNE4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110108,970,868 - 108,973,080 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604090,393,360 - 90,397,358 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcne4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248232,239,101 - 2,266,809 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248232,239,132 - 2,244,758 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005330541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000010992   ⟹   ENSSTOP00000009861
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365694,940,109 - 4,940,984 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000033184   ⟹   ENSSTOP00000025622
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365694,939,511 - 4,942,038 (+)Ensembl
RefSeq Acc Id: XM_005330541   ⟹   XP_005330598
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303178,596,335 - 178,599,723 (+)NCBI
SpeTri2.0NW_0049365694,939,477 - 4,942,096 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005330598 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000009861.2
  ENSSTOP00000025622.1
GenBank Protein KAG3275384 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005330598   ⟸   XM_005330541
- UniProtKB: A0A287CWE4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000009861   ⟸   ENSSTOT00000010992
Ensembl Acc Id: ENSSTOP00000025622   ⟸   ENSSTOT00000033184


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010997 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010992.2 UniProtKB/TrEMBL
  ENSSTOT00000033184.1 UniProtKB/TrEMBL
InterPro K_chnl_KCNE UniProtKB/TrEMBL
NCBI Gene Kcne4 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY E MEMBER 4 UniProtKB/TrEMBL
  PTHR15282 UniProtKB/TrEMBL
Pfam ISK_Channel UniProtKB/TrEMBL
PRINTS KCNECHANNEL UniProtKB/TrEMBL
UniProt A0A287CWE4 ENTREZGENE, UniProtKB/TrEMBL
  I3MGH0_ICTTR UniProtKB/TrEMBL