Tmprss2 (transmembrane serine protease 2) - Rat Genome Database

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Gene: Tmprss2 (transmembrane serine protease 2) Ictidomys tridecemlineatus
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Symbol: Tmprss2
Name: transmembrane serine protease 2
RGD ID: 12489641
Description: INVOLVED IN positive regulation of viral entry into host cell (ortholog); protein autoprocessing (ortholog); proteolysis (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Cancer Pain (ortholog); Coronavirus infectious disease (ortholog); FOUND IN nucleoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: transmembrane protease serine 2; transmembrane protease, serine 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497135,245,118 - 35,277,589 (-)NCBI
SpeTri2.0NW_0049365002,199,877 - 2,222,174 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Tmprss2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497135,245,118 - 35,277,589 (-)NCBI
SpeTri2.0NW_0049365002,199,877 - 2,222,174 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMPRSS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2141,464,300 - 41,531,116 (-)EnsemblGRCh38hg38GRCh38
GRCh382141,464,305 - 41,508,158 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372142,836,232 - 42,880,085 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362141,758,351 - 41,801,948 (-)NCBINCBI36hg18NCBI36
Build 342141,758,350 - 41,801,948NCBI
Celera2128,034,659 - 28,078,450 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2128,305,352 - 28,349,365 (-)NCBIHuRef
CHM1_12142,397,265 - 42,440,908 (-)NCBICHM1_1
Tmprss2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391697,365,882 - 97,460,741 (-)NCBIGRCm39mm39
GRCm39 Ensembl1697,365,882 - 97,412,395 (-)Ensembl
GRCm381697,564,682 - 97,659,541 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1697,564,682 - 97,611,195 (-)EnsemblGRCm38mm10GRCm38
MGSCv371697,786,289 - 97,832,802 (-)NCBIGRCm37mm9NCBIm37
MGSCv361697,719,598 - 97,766,111 (-)NCBImm8
Celera1698,625,511 - 98,672,561 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1657.53NCBI
Tmprss2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21136,934,306 - 36,973,779 (-)NCBI
Rnor_6.0 Ensembl1138,063,915 - 38,103,290 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01138,063,914 - 38,103,406 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01141,574,415 - 41,613,911 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,577,051 - 37,617,258 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11137,634,640 - 37,674,847 (-)NCBI
Celera1136,819,034 - 36,858,331 (-)NCBICelera
Cytogenetic Map11q12NCBI
Tmprss2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540740,957,122 - 40,976,644 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540740,958,562 - 40,985,415 (-)NCBIChiLan1.0ChiLan1.0
TMPRSS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12141,128,358 - 41,170,924 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2141,131,515 - 41,161,088 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02127,800,466 - 27,843,395 (-)NCBIMhudiblu_PPA_v0panPan3
TMPRSS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13135,933,082 - 35,968,732 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3135,087,922 - 35,123,133 (-)NCBI
ROS_Cfam_1.03135,451,094 - 35,486,696 (-)NCBI
UMICH_Zoey_3.13135,346,223 - 35,380,906 (-)NCBI
UNSW_CanFamBas_1.03135,325,381 - 35,360,709 (-)NCBI
UU_Cfam_GSD_1.03135,819,128 - 35,854,769 (-)NCBI
TMPRSS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13204,876,561 - 204,902,561 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113204,874,759 - 204,905,411 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213214,974,417 - 214,981,735 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMPRSS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1285,372,881 - 85,413,717 (-)NCBI
ChlSab1.1 Ensembl285,372,117 - 85,412,926 (-)Ensembl
Vero_WHO_p1.0NW_02366605413,228,416 - 13,267,943 (-)NCBI
Tmprss2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474528,565,515 - 28,593,102 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021725256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_021725256   ⟹   XP_021580931
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440497135,245,118 - 35,277,589 (-)NCBI
SpeTri2.0NW_0049365002,199,877 - 2,222,174 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021580931 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3284015 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_021580931   ⟸   XM_021725256
- Sequence:
Protein Domains
Peptidase S1   SRCR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000012868 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000011538 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000012873 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/TrEMBL
  3.10.250.10 UniProtKB/TrEMBL
  4.10.400.10 UniProtKB/TrEMBL
InterPro LDL_receptor-like_sf UniProtKB/TrEMBL
  LDLR_class-A_CS UniProtKB/TrEMBL
  LDrepeatLR_classA_rpt UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/TrEMBL
  Peptidase_S1_PA_chymotrypsin UniProtKB/TrEMBL
  Peptidase_S1A UniProtKB/TrEMBL
  SRCR UniProtKB/TrEMBL
  SRCR-like_dom UniProtKB/TrEMBL
  SRCR-like_dom_sf UniProtKB/TrEMBL
  Trypsin_dom UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
NCBI Gene Tmprss2 ENTREZGENE
Pfam Ldl_recept_a UniProtKB/TrEMBL
  SRCR_2 UniProtKB/TrEMBL
  Trypsin UniProtKB/TrEMBL
PRINTS CHYMOTRYPSIN UniProtKB/TrEMBL
PROSITE LDLRA_1 UniProtKB/TrEMBL
  LDLRA_2 UniProtKB/TrEMBL
  SRCR_2 UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/TrEMBL
  TRYPSIN_HIS UniProtKB/TrEMBL
  TRYPSIN_SER UniProtKB/TrEMBL
SMART LDLa UniProtKB/TrEMBL
  SM00202 UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/TrEMBL
Superfamily-SCOP SSF50494 UniProtKB/TrEMBL
  SSF56487 UniProtKB/TrEMBL
  SSF57424 UniProtKB/TrEMBL
UniProt I3MJY8_ICTTR UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-23 Tmprss2  transmembrane serine protease 2    transmembrane protease, serine 2  Symbol and/or name change 5135510 APPROVED