Serpina10 (serpin family A member 10)

Gene: Serpina10 (serpin family A member 10) Ictidomys tridecemlineatus

Analyze

Symbol:

Serpina10

Name:

serpin family A member 10

RGD ID:

12489128

Description:

INVOLVED IN liver regeneration (ortholog); regulation of acrosome reaction (ortholog); PARTICIPATES IN coagulation cascade pathway; ASSOCIATED WITH achondrogenesis type IA (ortholog); DICER1 syndrome (ortholog); genetic disease (ortholog)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	11,337,053 - 11,345,124 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936733	2,121,875 - 2,129,988 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

achondrogenesis type IA (ISO)

DICER1 syndrome (ISO)

genetic disease (ISO)

nephrotic syndrome type 5 (ISO)

pleuropulmonary blastoma (ISO)

thrombophilia (ISO)

Venous Thrombosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

liver regeneration (ISO)

regulation of acrosome reaction (ISO)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

coagulation cascade pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Serpina10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	11,337,053 - 11,345,124 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936733	2,121,875 - 2,129,988 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SERPINA10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	94,280,460 - 94,293,268 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	94,280,460 - 94,293,268 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	94,746,797 - 94,759,605 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	93,819,403 - 93,829,349 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	93,819,404 - 93,829,114	NCBI
Celera	14	74,803,423 - 74,813,369 (-)	NCBI		Celera
Cytogenetic Map	14	q32.13	NCBI
HuRef	14	74,929,448 - 74,939,406 (-)	NCBI		HuRef
CHM1_1	14	94,687,457 - 94,697,415 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	88,507,743 - 88,520,553 (-)	NCBI		T2T-CHM13v2.0

Serpina10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	103,582,934 - 103,597,681 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	103,581,045 - 103,597,703 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	103,616,675 - 103,631,490 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	103,614,786 - 103,631,444 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	104,854,885 - 104,869,615 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	104,017,725 - 104,032,455 (-)	NCBI		MGSCv36	mm8
Celera	12	104,832,950 - 104,847,686 (-)	NCBI		Celera
Cytogenetic Map	12	E	NCBI
cM Map	12	52.97	NCBI

Serpina10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	128,520,894 - 128,529,332 (-)	NCBI		GRCr8
mRatBN7.2	6	122,756,106 - 122,764,544 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	122,756,108 - 122,764,544 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	122,896,632 - 122,905,075 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	123,191,904 - 123,200,347 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	122,528,769 - 122,537,212 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	127,500,014 - 127,508,470 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	127,500,016 - 127,508,452 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	6	129,004,240 - 129,010,271 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	136,718,786 - 136,727,224 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	127,887,684 - 127,896,122 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	127,891,432 - 127,899,869 (-)	NCBI
Celera	6	120,236,372 - 120,244,810 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

Serpina10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	16,335,544 - 16,345,094 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	16,335,201 - 16,345,093 (-)	NCBI	ChiLan1.0	ChiLan1.0

SERPINA10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	95,441,471 - 95,448,088 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	94,656,249 - 94,664,593 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	74,914,680 - 74,927,325 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	94,248,362 - 94,258,301 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	94,248,362 - 94,257,835 (-)	Ensembl	panpan1.1		panPan2

SERPINA10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	72,059,523 - 72,069,989 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	72,058,780 - 72,069,085 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	59,292,823 - 59,299,933 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Serpina10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	10,620,620 - 10,631,306 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	10,619,044 - 10,630,963 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021735862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_021735862 ⟹ XP_021591537

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	11,337,053 - 11,345,124 (+)	NCBI
SpeTri2.0	NW_004936733	2,121,875 - 2,129,988 (-)	NCBI

Sequence:

show sequence

ATGGCTAAACAGAGAAGAGAAGAAGGAAAAAGCGAATCTGGAGAGAGGGATGTGGCCCCAAGCC
TCCTGCTCTCTGTCCTCCTGGCGGAGATGAGGCTGGTGCCTGGCCTGGCCCTTAGTCCTGGGTC
ACCAGAAGCCCAGGCAGAGATGGACACTCTGGAGCCTCAGCCTCCTCAGAACCAGACTCGGGTG
GCGGGAGTGCAGGCTCCTACTGATGGGGAAGATGAGCTGGGGACAGAGGGGGCCCTGAGCCACA
CCACGCCCCTGCTCCTGCCTNCCCTCTTTAAGCTGATCAGAGAGACCCTCTCCNACCAGCTGGG
CCTTGCCCAGGGGAGTTTTGCTTTCATCCACAAGGATTTTGATTGCAAAGAGACCTTCCCCAAT
TCACCCAAGAGGTCCCTTGATAAAGCATATGCCTGTGAATTTTCACAGTGCCCTCAGGCCCAGG
GGCTCATGAATNNATTACACAAAGAGCCTCAGGGGGAAGTTCTCCAGCTATTTGATGAGATTAA
TNATCAAACCAAATTGATTCTTGTGGATCACATCTTGTTCTGAGGGACTTGGATCATGGAAGCG
GCTGGCCTCATGTGGCCCACCTTCACCAAAGCTGACACTTTCCACCTGGACAAGTCCAAGGCAG
TCAAGGTGCCGGTGATGTACAGGGCAGGCAAGTCTGCCTCCACCTTTGATAAGAAGGTTCACTG
CCATGTCCTCCCACTGCCCTACTGAGGAAACGCCACCATGCTGGTGGTCCTCATGGGGAACACA
GGTGACCACCTGGCCCTGGAAGGTGGTCTGACCACAGAGCTGGTGGAGACATGGCTCAGGAACA
GGTTTTTTCACTCAGTGATTGAAGCTGATGAGAAAGGCACTGAGGCAGTTGCAGGAACCCCGTC
AGAAATCACTNNGTATTTCCTGCCTCCGGTCACCAAGGTGCCCTGGCCATTCCATTTGAGGGTC
TACAAGGAAACCTCGAGGGTGCTCCTATTCCTGCAGGGCGGTGAATCCAATCTCCTGTGACCCA
CAACCGGCATGAGCTCTCAGTGTGACAGCAGGTGCTCA

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Protein Sequences


Protein RefSeqs	XP_021591537	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_021591537 ⟸ XM_021735862

- Sequence:

show sequence

MAKQRREEGKSESGERDVAPSLLLSVLLAEMRLVPGLALSPGSPEAQAEMDTLEPQPPQNQTRV
AGVQAPTDGEDELGTEGALSHTTPLLLPXLFKLIRETLSXQLGLAQGSFAFIHKDFDCKETFPN
SPKRSLDKAYACEFSQCPQAQGLMNXLHKEPQGEVLQLFDEINXQTKLILVDHILFXGTWIMEA
AGLMWPTFTKADTFHLDKSKAVKVPVMYRAGKSASTFDKKVHCHVLPLPYXGNATMLVVLMGNT
GDHLALEGGLTTELVETWLRNRFFHSVIEADEKGTEAVAGTPSEITXYFLPPVTKVPWPFHLRV
YKETSRVLLFLQGGESNLL

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Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Serpina10	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations