Znf451 (zinc finger protein 451) - Rat Genome Database

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Gene: Znf451 (zinc finger protein 451) Ictidomys tridecemlineatus
Analyze
Symbol: Znf451
Name: zinc finger protein 451
RGD ID: 12488754
Description: ENCODES a protein that exhibits transcription corepressor activity (ortholog); transcription regulator inhibitor activity (ortholog); INVOLVED IN negative regulation of transcription initiation by RNA polymerase II (ortholog); negative regulation of transforming growth factor beta receptor signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); schizophrenia (ortholog); FOUND IN nucleus (ortholog); PML body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BCL2 associated athanogene 2; E3 SUMO-protein ligase ZNF451; Kiaa1586
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494659,691,337 - 59,827,796 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364764,133,803 - 4,268,834 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (ISO)
PML body  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Znf451
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494659,691,337 - 59,827,796 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049364764,133,803 - 4,268,834 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF451
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38657,090,188 - 57,170,305 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl657,086,844 - 57,170,305 (+)EnsemblGRCh38hg38GRCh38
GRCh37656,954,986 - 57,035,103 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36657,062,787 - 57,143,057 (+)NCBINCBI36Build 36hg18NCBI36
Build 34657,062,786 - 57,142,958NCBI
Celera658,617,929 - 58,698,197 (+)NCBICelera
Cytogenetic Map6p12.1NCBI
HuRef656,788,725 - 56,869,155 (+)NCBIHuRef
CHM1_1656,955,130 - 57,035,424 (+)NCBICHM1_1
T2T-CHM13v2.0656,929,190 - 57,009,330 (+)NCBIT2T-CHM13v2.0
Zfp451
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39133,800,622 - 33,854,683 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl133,800,626 - 33,853,676 (-)EnsemblGRCm39 Ensembl
GRCm38133,761,541 - 33,815,602 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl133,761,545 - 33,814,595 (-)EnsemblGRCm38mm10GRCm38
MGSCv37133,818,598 - 33,871,272 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36133,706,299 - 33,758,973 (-)NCBIMGSCv36mm8
Celera133,536,759 - 33,589,408 (-)NCBICelera
Cytogenetic Map1BNCBI
cM Map112.81NCBI
Zfp451
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8943,481,395 - 43,546,103 (-)NCBIGRCr8
mRatBN7.2935,985,441 - 36,040,991 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl935,985,443 - 36,040,652 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx944,482,359 - 44,537,564 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0949,613,545 - 49,668,749 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0947,895,463 - 47,950,664 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0938,395,464 - 38,451,585 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl938,396,449 - 38,451,656 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0938,077,865 - 38,133,122 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4932,506,481 - 32,561,688 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1932,493,198 - 32,563,138 (-)NCBI
Celera933,778,050 - 33,833,256 (-)NCBICelera
Cytogenetic Map9q21NCBI
Znf451
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555022,999,976 - 3,048,464 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555023,003,822 - 3,087,529 (-)NCBIChiLan1.0ChiLan1.0
ZNF451
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2571,526,373 - 71,640,442 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1667,439,104 - 67,521,873 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0656,647,589 - 56,728,231 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1658,279,387 - 58,358,935 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl658,279,387 - 58,358,935 (+)Ensemblpanpan1.1panPan2
ZNF451
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11224,260,862 - 24,350,890 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1224,260,917 - 24,350,559 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1224,190,937 - 24,281,090 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01224,800,454 - 24,890,532 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1224,759,097 - 24,889,668 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11224,297,632 - 24,387,762 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01224,398,988 - 24,489,097 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01224,530,360 - 24,620,506 (+)NCBIUU_Cfam_GSD_1.0
ZNF451
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl728,681,961 - 28,765,326 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1728,682,284 - 28,765,489 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2733,142,449 - 33,226,658 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZNF451
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11714,434,878 - 14,516,914 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1714,433,977 - 14,516,788 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605820,529,352 - 20,612,854 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf451
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475318,884,454 - 18,975,400 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475318,859,416 - 18,974,016 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005318528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005318529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021721789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021721790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021721791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021721792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021721793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021721794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021721795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021721796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021721797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021721798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_040282878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005318528   ⟹   XP_005318585
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,725,188 - 59,814,753 (+)NCBI
SpeTri2.0NW_0049364764,145,415 - 4,234,992 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005318529   ⟹   XP_005318586
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,725,182 - 59,744,254 (+)NCBI
SpeTri2.0NW_0049364764,215,950 - 4,235,705 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021721792   ⟹   XP_021577467
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,344 - 59,814,753 (+)NCBI
SpeTri2.0NW_0049364764,145,415 - 4,268,834 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021721793   ⟹   XP_021577468
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,343 - 59,814,753 (+)NCBI
SpeTri2.0NW_0049364764,145,415 - 4,268,834 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021721794   ⟹   XP_021577469
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,343 - 59,814,753 (+)NCBI
SpeTri2.0NW_0049364764,145,415 - 4,268,834 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021721798   ⟹   XP_021577473
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,337 - 59,701,233 (+)NCBI
SpeTri2.0NW_0049364764,260,123 - 4,268,834 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040282864   ⟹   XP_040138798
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,343 - 59,814,753 (+)NCBI
RefSeq Acc Id: XM_040282866   ⟹   XP_040138800
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,343 - 59,826,445 (+)NCBI
RefSeq Acc Id: XM_040282867   ⟹   XP_040138801
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,343 - 59,814,753 (+)NCBI
RefSeq Acc Id: XM_040282868   ⟹   XP_040138802
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,343 - 59,826,445 (+)NCBI
RefSeq Acc Id: XM_040282869   ⟹   XP_040138803
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,343 - 59,814,753 (+)NCBI
RefSeq Acc Id: XM_040282870   ⟹   XP_040138804
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,343 - 59,814,753 (+)NCBI
RefSeq Acc Id: XM_040282871   ⟹   XP_040138805
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,343 - 59,814,753 (+)NCBI
RefSeq Acc Id: XM_040282872   ⟹   XP_040138806
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,343 - 59,826,441 (+)NCBI
RefSeq Acc Id: XM_040282873   ⟹   XP_040138807
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,344 - 59,827,796 (+)NCBI
RefSeq Acc Id: XM_040282875   ⟹   XP_040138809
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,691,344 - 59,814,753 (+)NCBI
RefSeq Acc Id: XM_040282876   ⟹   XP_040138810
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,749,489 - 59,814,753 (+)NCBI
RefSeq Acc Id: XM_040282877   ⟹   XP_040138811
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,735,739 - 59,814,753 (+)NCBI
RefSeq Acc Id: XM_040282878   ⟹   XP_040138812
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494659,735,558 - 59,814,753 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005318585   ⟸   XM_005318528
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_005318586   ⟸   XM_005318529
- Peptide Label: isoform X13
- UniProtKB: A0A287D8B4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021577467   ⟸   XM_021721792
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021577469   ⟸   XM_021721794
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021577468   ⟸   XM_021721793
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021577473   ⟸   XM_021721798
- Peptide Label: isoform X12
- UniProtKB: A0A287CYE1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040138800   ⟸   XM_040282866
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040138802   ⟸   XM_040282868
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040138806   ⟸   XM_040282872
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040138798   ⟸   XM_040282864
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040138805   ⟸   XM_040282871
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040138804   ⟸   XM_040282870
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040138801   ⟸   XM_040282867
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040138803   ⟸   XM_040282869
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040138807   ⟸   XM_040282873
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040138809   ⟸   XM_040282875
- Peptide Label: isoform X7
RefSeq Acc Id: XP_040138812   ⟸   XM_040282878
- Peptide Label: isoform X11
RefSeq Acc Id: XP_040138811   ⟸   XM_040282877
- Peptide Label: isoform X10
RefSeq Acc Id: XP_040138810   ⟸   XM_040282876
- Peptide Label: isoform X9
Protein Domains
Lamina-associated polypeptide 2 alpha C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000025191 UniProtKB/TrEMBL
  ENSSTOG00000032091 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000030700.1 UniProtKB/TrEMBL
  ENSSTOT00000033053.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.3160 UniProtKB/TrEMBL
InterPro LAP2alpha_C UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/TrEMBL
NCBI Gene Znf451 ENTREZGENE
PANTHER E3 SUMO-PROTEIN LIGASE KIAA1586 UniProtKB/TrEMBL
  RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam LAP2alpha UniProtKB/TrEMBL
Superfamily-SCOP Ribonuclease H-like UniProtKB/TrEMBL
UniProt A0A287CYE1 ENTREZGENE, UniProtKB/TrEMBL
  A0A287D8B4 ENTREZGENE, UniProtKB/TrEMBL