Grm2 (glutamate metabotropic receptor 2) - Rat Genome Database

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Gene: Grm2 (glutamate metabotropic receptor 2) Ictidomys tridecemlineatus
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Symbol: Grm2
Name: glutamate metabotropic receptor 2
RGD ID: 12485564
Description: ENCODES a protein that exhibits group II metabotropic glutamate receptor activity (ortholog); scaffold protein binding (ortholog); INVOLVED IN behavioral response to nicotine (ortholog); cellular response to stress (ortholog); gene expression (ortholog); ASSOCIATED WITH amphetamine abuse (ortholog); Binge Drinking (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN astrocyte projection (ortholog); axon (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: metabotropic glutamate receptor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560266,281,725 - 66,293,182 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365293,042,248 - 3,053,673 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365293,042,220 - 3,053,670 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Grm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560266,281,725 - 66,293,182 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365293,042,248 - 3,053,673 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365293,042,220 - 3,053,670 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38351,707,068 - 51,718,613 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl351,707,068 - 51,718,613 (+)EnsemblGRCh38hg38GRCh38
GRCh37351,741,084 - 51,752,629 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36351,718,004 - 51,727,669 (+)NCBINCBI36Build 36hg18NCBI36
Build 34351,718,037 - 51,727,168NCBI
Celera351,718,848 - 51,731,506 (+)NCBICelera
Cytogenetic Map3p21.2NCBI
HuRef351,802,839 - 51,816,142 (+)NCBIHuRef
CHM1_1351,693,893 - 51,705,447 (+)NCBICHM1_1
T2T-CHM13v2.0351,738,578 - 51,751,605 (+)NCBIT2T-CHM13v2.0
Grm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,521,733 - 106,533,308 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9106,520,294 - 106,533,281 (-)EnsemblGRCm39 Ensembl
GRCm389106,644,534 - 106,656,109 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,643,095 - 106,656,082 (-)EnsemblGRCm38mm10GRCm38
MGSCv379106,546,865 - 106,558,440 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369106,546,755 - 106,558,434 (-)NCBIMGSCv36mm8
Celera9106,265,562 - 106,277,130 (-)NCBICelera
Cytogenetic Map9F1NCBI
cM Map957.98NCBI
Grm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88116,158,810 - 116,171,857 (-)NCBIGRCr8
mRatBN7.28107,280,099 - 107,293,159 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8107,280,099 - 107,293,146 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8112,903,031 - 112,916,129 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08111,102,213 - 111,115,309 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08108,944,991 - 108,958,085 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08115,344,999 - 115,358,628 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,344,999 - 115,358,046 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,705,123 - 114,718,193 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48111,837,086 - 111,850,133 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18111,857,819 - 111,869,581 (-)NCBI
Celera8106,592,051 - 106,605,096 (-)NCBICelera
Cytogenetic Map8q32NCBI
Grm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555323,309,028 - 3,320,966 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555323,309,034 - 3,320,954 (+)NCBIChiLan1.0ChiLan1.0
GRM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2251,694,559 - 51,707,434 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1351,699,333 - 51,712,208 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0351,639,792 - 51,652,779 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1352,873,144 - 52,884,401 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl352,873,144 - 52,884,395 (+)Ensemblpanpan1.1panPan2
GRM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,915,178 - 37,926,276 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,915,665 - 37,924,296 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,895,193 - 37,906,256 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02038,264,331 - 38,275,394 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2038,264,304 - 38,275,372 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,627,888 - 37,638,953 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02038,036,604 - 38,047,669 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02038,321,755 - 38,332,818 (-)NCBIUU_Cfam_GSD_1.0
GRM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1333,926,804 - 33,938,269 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11333,924,303 - 33,938,279 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,130,553 - 37,141,351 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,044,974 - 13,056,469 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,046,641 - 13,056,453 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,898,374 - 153,910,372 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247305,419,896 - 5,431,361 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247305,419,892 - 5,431,268 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Sequence


Ensembl Acc Id: ENSSTOT00000024816   ⟹   ENSSTOP00000019116
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365293,042,248 - 3,053,673 (+)Ensembl
Ensembl Acc Id: ENSSTOT00000039107   ⟹   ENSSTOP00000024848
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365293,044,319 - 3,053,182 (+)Ensembl
RefSeq Acc Id: XM_005326974   ⟹   XP_005327031
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560266,281,725 - 66,293,182 (+)NCBI
SpeTri2.0NW_0049365293,042,220 - 3,053,670 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040269778   ⟹   XP_040125712
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560266,281,726 - 66,293,182 (+)NCBI
RefSeq Acc Id: XM_040269779   ⟹   XP_040125713
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560266,284,140 - 66,293,182 (+)NCBI
RefSeq Acc Id: XM_040269780   ⟹   XP_040125714
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560266,281,725 - 66,293,182 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005327031 (Get FASTA)   NCBI Sequence Viewer  
  XP_040125712 (Get FASTA)   NCBI Sequence Viewer  
  XP_040125713 (Get FASTA)   NCBI Sequence Viewer  
  XP_040125714 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019116.1
  ENSSTOP00000024848.1
GenBank Protein KAG3270584 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005327031   ⟸   XM_005326974
- Peptide Label: isoform X1
- UniProtKB: I3N420 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040125714   ⟸   XM_040269780
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040125712   ⟸   XM_040269778
- Peptide Label: isoform X1
- UniProtKB: I3N420 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040125713   ⟸   XM_040269779
- Peptide Label: isoform X2
Ensembl Acc Id: ENSSTOP00000024848   ⟸   ENSSTOT00000039107
Ensembl Acc Id: ENSSTOP00000019116   ⟸   ENSSTOT00000024816
Protein Domains
G-protein coupled receptors family 3 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000027783 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024816.2 UniProtKB/TrEMBL
  ENSSTOT00000039107.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.50.30 UniProtKB/TrEMBL
  3.40.50.2300 UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/TrEMBL
  GPCR_3 UniProtKB/TrEMBL
  GPCR_3_9-Cys_dom UniProtKB/TrEMBL
  GPCR_3_9-Cys_sf UniProtKB/TrEMBL
  GPCR_3_C UniProtKB/TrEMBL
  GPCR_3_CS UniProtKB/TrEMBL
  GPCR_3_mtglu_rcpt UniProtKB/TrEMBL
  GPCR_3_mtglu_rcpt_2 UniProtKB/TrEMBL
  mGluR UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
NCBI Gene Grm2 ENTREZGENE
PANTHER METABOTROPIC GLUTAMATE RECEPTOR UniProtKB/TrEMBL
  METABOTROPIC GLUTAMATE RECEPTOR 2 UniProtKB/TrEMBL
Pfam 7tm_3 UniProtKB/TrEMBL
  ANF_receptor UniProtKB/TrEMBL
  NCD3G UniProtKB/TrEMBL
PRINTS GPCRMGR UniProtKB/TrEMBL
  MTABOTROPC2R UniProtKB/TrEMBL
  MTABOTROPICR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F3_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_2 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F3_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF53822 UniProtKB/TrEMBL
UniProt A0A287CUA3_ICTTR UniProtKB/TrEMBL
  I3N420 ENTREZGENE, UniProtKB/TrEMBL