Marchf11 (membrane associated ring-CH-type finger 11)

Gene: Marchf11 (membrane associated ring-CH-type finger 11) Ictidomys tridecemlineatus

Analyze

Symbol:

Marchf11

Name:

membrane associated ring-CH-type finger 11

RGD ID:

12484504

Description:

ENCODES a protein that exhibits ubiquitin-protein transferase activity (inferred); zinc ion binding (inferred); INVOLVED IN protein ubiquitination (inferred); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

E3 ubiquitin-protein ligase MARCH11; E3 ubiquitin-protein ligase MARCHF11; March11

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	231,780,060 - 231,893,739 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936665	373,585 - 487,468 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936665	373,585 - 485,253 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein ubiquitination (IEA)

Cellular Component

membrane (IEA)

Molecular Function

ubiquitin-protein transferase activity (IEA)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Marchf11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	231,780,060 - 231,893,739 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936665	373,585 - 487,468 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936665	373,585 - 485,253 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MARCHF11
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	16,067,139 - 16,179,791 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	16,067,139 - 16,180,762 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	16,067,248 - 16,179,900 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	16,120,474 - 16,232,897 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	16,091,141 - 16,203,521 (-)	NCBI		Celera
Cytogenetic Map	5	p15.1	NCBI
HuRef	5	16,039,821 - 16,151,852 (-)	NCBI		HuRef
CHM1_1	5	16,067,446 - 16,179,865 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	16,006,508 - 16,119,114 (-)	NCBI		T2T-CHM13v2.0

Marchf11
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	26,309,134 - 26,409,672 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	26,309,134 - 26,409,662 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	26,309,048 - 26,409,586 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	26,309,048 - 26,409,576 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	26,238,827 - 26,339,328 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	26,253,773 - 26,257,096 (+)	NCBI		MGSCv36	mm8
Celera	15	27,066,431 - 27,166,981 (+)	NCBI		Celera
Cytogenetic Map	15	B1	NCBI
cM Map	15	9.77	NCBI

Marchf11
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	78,628,793 - 78,730,164 (+)	NCBI		GRCr8
mRatBN7.2	2	76,898,330 - 76,999,690 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	76,898,386 - 76,999,691 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	84,021,267 - 84,122,494 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	82,142,989 - 82,244,218 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	77,143,107 - 77,244,792 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	78,825,053 - 78,926,402 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	78,825,074 - 78,926,395 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	98,502,837 - 98,603,756 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	77,989,651 - 78,090,956 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	72,587,971 - 72,689,328 (+)	NCBI		Celera
Cytogenetic Map	2	q22	NCBI

Marchf11
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955426	5,161,797 - 5,278,267 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955426	5,161,960 - 5,279,739 (-)	NCBI	ChiLan1.0	ChiLan1.0

MARCHF11
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	16,292,990 - 16,407,484 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	14,446,601 - 14,561,088 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	16,365,004 - 16,477,440 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	16,202,913 - 16,316,144 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

MARCHF11
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	87,138,291 - 87,245,060 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	86,669,895 - 86,765,429 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	87,772,866 - 87,879,398 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	4	87,295,125 - 87,401,252 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	87,538,033 - 87,644,577 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	88,389,334 - 88,495,848 (+)	NCBI		UU_Cfam_GSD_1.0

MARCHF11
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	5,346,133 - 5,460,003 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	5,345,490 - 5,459,893 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	5,778,353 - 5,939,960 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MARCHF11
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	15,746,426 - 15,862,799 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	15,746,015 - 15,860,118 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666064	12,611,484 - 12,725,581 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Marchf11
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624751	12,949,527 - 13,076,340 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005336748	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010002273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000015945 ⟹ ENSSTOP00000014267

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936665	373,585 - 487,468 (+)	Ensembl

RefSeq Acc Id:

XM_005336748 ⟹ XP_005336805

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024407213	231,780,060 - 231,893,739 (+)	NCBI
SpeTri2.0	NW_004936665	373,585 - 485,253 (+)	NCBI

Sequence:

show sequence

GGCGGCGGCGGCGACCAACGCGCCGGGCACCAGCACCAGCATCACCAGCCCATCTGCAAGATCT
GCTTCCAGGGCGCGGAGCAGGGAGAGCTATTAAATCCCTGCCGATGTGATGGGTCAGTTCGGTA
CACACACCAACTGTGCCTGCTCAAGTGGATCAGTGAGAGAGGCTCCTGGACCTGCGAGCTCTGC
TGTTATAGATACCACGTGATAGCCATTAAGATGAAACAACCTTGCCAGTGGCAAAGCATTTCTA
TAACACTGGTTGAGAAAGTTCAGATGATTGCTGTAATCCTAGGATCCCTGTTCTTAATAGCGAG
TGTGACGTGGCTCCTCTGGTCAGCCTTCAGCCCTTATGCAGTGTGGCAGAGGAAGGACATCCTT
TTTCAGATCTGCTATGGAATGTATGGTTTTATGGATCTAGTGTGCATAGGTCTCATTGTCCATG
AAGGAGCTGCAGTTTACAGAGTGTTTAAACGCTGGAGAGCTGTGAATTTGCACTGGGATGTGTT
AAATTATGACAAAGCCACAGACATTGAAGAGAGCAGCCGGGGAGAGTCTTCCACGAGTAGGACT
TTATGGTTGCCACTGACGGCTCTGCGGAGCAGAAACTTGGTCCACCCAACGCAGCTCACCTCGC
CAAGGTTCCAGTGTGGCTACGTGCTCTTGCATCTCTTCAACCGGATGAGGCCCCAGGAGGATTT
GTCAGAAGATAACAGCTCGGGAGAGGTTGTGATGAGAGTGACTTCAGTGTGACAAACACATTTG
ATGATGCAGTGCGGACCACCCTGCACATTTCGGAATGTAATTGCAATGAATGGAGAAACCATAG
CACTTCTAAAAAAAAACACTCATCTATGAACTTTTTAAAATTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005336805	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000014267.2
GenBank Protein	KAG3266865	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005336805 ⟸ XM_005336748

- Sequence:

show sequence

GGGGDQRAGHQHQHHQPICKICFQGAEQGELLNPCRCDGSVRYTHQLCLLKWISERGSWTCELC
CYRYHVIAIKMKQPCQWQSISITLVEKVQMIAVILGSLFLIASVTWLLWSAFSPYAVWQRKDIL
FQICYGMYGFMDLVCIGLIVHEGAAVYRVFKRWRAVNLHWDVLNYDKATDIEESSRGESSTSRT
LWLPLTALRSRNLVHPTQLTSPRFQCGYVLLHLFNRMRPQEDLSEDNSSGEVVMRVTSV

hide sequence

RefSeq Acc Id:

ENSSTOP00000014267 ⟸ ENSSTOT00000015945

Protein Domains

RING-CH-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000015947	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000015945.3	UniProtKB/TrEMBL
Gene3D-CATH	3.30.40.10	UniProtKB/TrEMBL
InterPro	MARCHF4/9/11	UniProtKB/TrEMBL
	Znf_RING-CH	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
NCBI Gene	March11	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE MARCHF11	UniProtKB/TrEMBL
	PTHR46053	UniProtKB/TrEMBL
Pfam	RINGv	UniProtKB/TrEMBL
PROSITE	ZF_RING_CH	UniProtKB/TrEMBL
SMART	RINGv	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
UniProt	I3MQM3_ICTTR	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-07-16	Marchf11	membrane associated ring-CH-type finger 11	March11	membrane associated ring-CH-type finger 11	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar