Mknk1 (MAPK interacting serine/threonine kinase 1) - Rat Genome Database

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Gene: Mknk1 (MAPK interacting serine/threonine kinase 1) Ictidomys tridecemlineatus
Analyze
Symbol: Mknk1
Name: MAPK interacting serine/threonine kinase 1
RGD ID: 12484385
Description: ENCODES a protein that exhibits ATP binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN extrinsic apoptotic signaling pathway in absence of ligand (ortholog); intracellular signal transduction (ortholog); peptidyl-serine phosphorylation (ortholog); PARTICIPATES IN cyclooxygenase mediated pathway of arachidonic acid metabolism; p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; ASSOCIATED WITH genetic disease (ortholog); substance-related disorder (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: MAP kinase interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505861,743,543 - 61,786,599 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647427,568,325 - 27,611,315 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Mknk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505861,743,543 - 61,786,599 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647427,568,325 - 27,611,315 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MKNK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38146,557,407 - 46,604,268 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl146,557,407 - 46,616,843 (-)EnsemblGRCh38hg38GRCh38
GRCh37147,023,079 - 47,069,940 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36146,795,677 - 46,842,473 (-)NCBINCBI36Build 36hg18NCBI36
Celera145,310,474 - 45,357,318 (-)NCBICelera
Cytogenetic Map1p33NCBI
HuRef145,138,599 - 45,185,470 (-)NCBIHuRef
CHM1_1147,140,090 - 47,186,977 (-)NCBICHM1_1
T2T-CHM13v2.0146,434,628 - 46,481,501 (-)NCBIT2T-CHM13v2.0
Mknk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394115,695,140 - 115,736,453 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4115,696,395 - 115,736,447 (+)EnsemblGRCm39 Ensembl
GRCm384115,837,943 - 115,879,256 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4115,839,198 - 115,879,250 (+)EnsemblGRCm38mm10GRCm38
MGSCv374115,511,851 - 115,551,853 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364115,337,178 - 115,377,180 (+)NCBIMGSCv36mm8
Celera4114,578,978 - 114,618,975 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.06NCBI
Mknk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,554,881 - 134,594,392 (+)NCBIGRCr8
mRatBN7.25129,318,128 - 129,357,641 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,318,170 - 129,357,639 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5131,935,265 - 131,974,307 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05133,690,135 - 133,729,177 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05133,712,289 - 133,751,335 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05134,691,852 - 134,730,887 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5134,691,881 - 134,730,893 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05138,476,301 - 138,514,361 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45136,100,236 - 136,141,344 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5127,849,685 - 127,888,824 (+)NCBICelera
Cytogenetic Map5q35NCBI
Mknk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546411,707,614 - 11,750,562 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546411,697,946 - 11,750,258 (+)NCBIChiLan1.0ChiLan1.0
MKNK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21180,204,666 - 180,251,570 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11179,346,289 - 179,393,176 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,859,888 - 45,906,840 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1147,215,693 - 47,262,324 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl147,215,693 - 47,262,317 (-)Ensemblpanpan1.1panPan2
MKNK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11513,857,495 - 13,898,709 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1513,857,553 - 13,898,723 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1513,978,161 - 14,019,402 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01514,008,202 - 14,049,444 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,008,192 - 14,049,444 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11513,809,430 - 13,850,723 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01513,878,036 - 13,919,318 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01513,947,345 - 13,988,638 (+)NCBIUU_Cfam_GSD_1.0
MKNK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6164,887,748 - 164,933,521 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16164,887,707 - 164,933,526 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26152,376,955 - 152,423,383 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MKNK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12086,202,953 - 86,250,574 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2086,204,502 - 86,250,712 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603330,741,656 - 30,788,020 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mknk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249062,439,418 - 2,473,967 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249062,442,590 - 2,494,724 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_040289172   ⟹   XP_040145106
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505861,743,543 - 61,786,599 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040145106 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040145106   ⟸   XM_040289172


Additional Information

Database Acc Id Source(s)
NCBI Gene Mknk1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-16 Mknk1  MAPK interacting serine/threonine kinase 1    MAP kinase interacting serine/threonine kinase 1  Symbol and/or name change 5135510 APPROVED