Cdc73 (cell division cycle 73) - Rat Genome Database

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Gene: Cdc73 (cell division cycle 73) Ictidomys tridecemlineatus
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Symbol: Cdc73
Name: cell division cycle 73
RGD ID: 12483007
Description: ENCODES a protein that exhibits RNA polymerase II complex binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); endodermal cell fate commitment (ortholog); histone H2B ubiquitination (ortholog); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription elongation pathway; ASSOCIATED WITH Breast Cancer, Familial (ortholog); Familial Cystic Parathyroid Adenomatosis (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN Cdc73/Paf1 complex (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: parafibromin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934480,662,470 - 80,779,375 (-)NCBI
SpeTri2.0NW_0049366381,365,457 - 1,482,497 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Cdc73
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934480,662,470 - 80,779,375 (-)NCBI
SpeTri2.0NW_0049366381,365,457 - 1,482,497 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC73
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1193,121,983 - 193,254,815 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1193,121,958 - 193,254,815 (+)EnsemblGRCh38hg38GRCh38
GRCh381193,122,031 - 193,254,815 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371193,091,161 - 193,223,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361191,357,784 - 191,487,679 (+)NCBINCBI36hg18NCBI36
Build 341189,822,817 - 189,952,713NCBI
Celera1166,200,694 - 166,333,560 (+)NCBI
Cytogenetic Map1q31.2NCBI
HuRef1164,326,911 - 164,459,852 (+)NCBIHuRef
CHM1_11194,512,977 - 194,645,669 (+)NCBICHM1_1
Cdc73
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391143,479,014 - 143,578,631 (-)NCBIGRCm39mm39
GRCm39 Ensembl1143,474,538 - 143,578,631 (-)Ensembl
GRCm381143,603,276 - 143,702,893 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1143,598,800 - 143,702,893 (-)EnsemblGRCm38mm10GRCm38
MGSCv371145,454,629 - 145,549,814 (-)NCBIGRCm37mm9NCBIm37
MGSCv361145,369,717 - 145,464,902 (-)NCBImm8
Celera1146,186,403 - 146,281,769 (-)NCBICelera
Cytogenetic Map1FNCBI
cM Map162.52NCBI
Cdc73
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21355,357,226 - 55,449,690 (-)NCBI
Rnor_6.0 Ensembl1360,403,771 - 60,496,511 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01360,403,771 - 60,496,511 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01365,392,579 - 65,485,175 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41357,441,674 - 57,534,385 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11357,455,753 - 57,548,465 (-)NCBI
Celera1355,444,707 - 55,537,113 (-)NCBICelera
Cytogenetic Map13q21NCBI
Cdc73
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540630,533,060 - 30,665,812 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540630,533,919 - 30,665,812 (+)NCBIChiLan1.0ChiLan1.0
CDC73
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11172,875,365 - 173,004,942 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1172,875,365 - 173,004,934 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01168,581,730 - 168,710,915 (+)NCBIMhudiblu_PPA_v0panPan3
CDC73
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1385,826,209 - 5,937,930 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl385,805,916 - 5,938,111 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha385,923,156 - 6,034,975 (-)NCBI
ROS_Cfam_1.0385,842,156 - 5,954,484 (-)NCBI
UMICH_Zoey_3.1385,841,710 - 5,953,973 (-)NCBI
UNSW_CanFamBas_1.0386,206,980 - 6,319,388 (-)NCBI
UU_Cfam_GSD_1.0386,435,831 - 6,547,946 (-)NCBI
CDC73
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl10575,074 - 667,434 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.110575,075 - 667,618 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2102,279,054 - 2,305,137 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDC73
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12536,167,482 - 36,302,918 (-)NCBI
ChlSab1.1 Ensembl2536,170,134 - 36,302,812 (-)Ensembl
Cdc73
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624814298,015 - 460,314 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005335354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010004404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005335354   ⟹   XP_005335411
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934480,662,470 - 80,779,375 (-)NCBI
SpeTri2.0NW_0049366381,365,457 - 1,482,497 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005335411 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005335411   ⟸   XM_005335354
- UniProtKB: I3N667 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
CDC73_C   CDC73_N


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000019765 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000019863 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000029990 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.11990 UniProtKB/TrEMBL
InterPro Cdc73/Parafibromin UniProtKB/TrEMBL
  CDC73_C UniProtKB/TrEMBL
  CDC73_C_sf UniProtKB/TrEMBL
  Cdc73_N UniProtKB/TrEMBL
NCBI Gene Cdc73 ENTREZGENE
PANTHER PTHR12466 UniProtKB/TrEMBL
Pfam CDC73_C UniProtKB/TrEMBL
  CDC73_N UniProtKB/TrEMBL
UniProt I3N667 ENTREZGENE, UniProtKB/TrEMBL