P2rx5 (purinergic receptor P2X 5) - Rat Genome Database

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Gene: P2rx5 (purinergic receptor P2X 5) Ictidomys tridecemlineatus
Analyze
Symbol: P2rx5
Name: purinergic receptor P2X 5
RGD ID: 12478005
Description: ENCODES a protein that exhibits ATP-gated ion channel activity (ortholog); extracellularly ATP-gated monoatomic cation channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN chloride transport (ortholog); excitatory postsynaptic potential (ortholog); monoatomic cation transmembrane transport (ortholog); ASSOCIATED WITH Canavan disease (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: P2X purinoceptor 5; purinergic receptor P2X 5, transcript variant X1; purinergic receptor P2X 5, transcript variant X2; purinergic receptor P2X 5, transcript variant X3; purinergic receptor P2X, ligand-gated ion channel, 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560255,515,339 - 55,530,836 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936677370,138 - 385,649 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936677370,141 - 385,669 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
membrane  (IEA)
plasma membrane  (IEA)
postsynapse  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
P2rx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560255,515,339 - 55,530,836 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936677370,138 - 385,649 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936677370,141 - 385,669 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
P2RX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38173,673,227 - 3,696,155 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl173,672,199 - 3,696,240 (-)EnsemblGRCh38hg38GRCh38
GRCh37173,576,521 - 3,599,449 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36173,523,270 - 3,546,332 (-)NCBINCBI36Build 36hg18NCBI36
Build 34173,523,272 - 3,546,332NCBI
Celera173,590,263 - 3,611,320 (-)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef173,468,232 - 3,490,048 (-)NCBIHuRef
CHM1_1173,587,157 - 3,608,787 (-)NCBICHM1_1
T2T-CHM13v2.0173,562,283 - 3,584,749 (-)NCBIT2T-CHM13v2.0
P2rx5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391173,029,164 - 73,063,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1173,051,247 - 73,063,511 (+)EnsemblGRCm39 Ensembl
GRCm381173,155,389 - 73,172,687 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1173,160,421 - 73,172,685 (+)EnsemblGRCm38mm10GRCm38
MGSCv371172,974,032 - 72,986,189 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361172,976,720 - 72,988,880 (+)NCBIMGSCv36mm8
Celera1180,697,612 - 80,709,777 (+)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.25NCBI
P2rx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81058,276,329 - 58,291,108 (+)NCBIGRCr8
mRatBN7.21057,777,737 - 57,789,426 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1057,777,819 - 57,789,423 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1062,433,638 - 62,445,218 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01061,922,089 - 61,933,678 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01057,421,249 - 57,432,831 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01059,725,438 - 59,737,126 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1059,725,398 - 59,737,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01059,464,489 - 59,476,098 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41060,036,074 - 60,047,683 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11060,049,703 - 60,061,303 (+)NCBI
Celera1056,901,047 - 56,912,634 (+)NCBICelera
Cytogenetic Map10q24NCBI
P2rx5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546713,126,116 - 13,139,768 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546713,125,710 - 13,140,031 (+)NCBIChiLan1.0ChiLan1.0
P2RX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21911,281,816 - 11,307,884 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11713,247,323 - 13,273,351 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0173,722,117 - 3,745,833 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1173,720,232 - 3,735,656 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl173,719,457 - 3,739,709 (-)Ensemblpanpan1.1panPan2
P2RX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1947,500,593 - 47,516,790 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha946,662,847 - 46,679,019 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0948,345,924 - 48,362,108 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl948,345,926 - 48,362,078 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1947,123,686 - 47,139,818 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0947,412,831 - 47,428,998 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0947,468,460 - 47,484,856 (-)NCBIUU_Cfam_GSD_1.0
P2RX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1249,778,800 - 49,796,110 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11249,780,241 - 49,796,287 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21251,643,316 - 51,649,939 (-)NCBISscrofa10.2Sscrofa10.2susScr3
P2RX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,173,215 - 3,198,262 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,180,595 - 3,196,341 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605918,597,921 - 18,612,118 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
P2rx5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247866,327,419 - 6,342,980 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247866,327,132 - 6,343,040 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000028726   ⟹   ENSSTOP00000014936
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936677370,138 - 385,649 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000041176   ⟹   ENSSTOP00000031044
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936677370,138 - 385,649 (-)Ensembl
RefSeq Acc Id: XM_005337309   ⟹   XP_005337366
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560255,515,349 - 55,530,836 (+)NCBI
SpeTri2.0NW_004936677370,141 - 385,669 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013363785   ⟹   XP_013219239
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560255,515,339 - 55,530,836 (+)NCBI
SpeTri2.0NW_004936677370,141 - 385,669 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040269548   ⟹   XP_040125482
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560255,515,457 - 55,526,599 (+)NCBI
RefSeq Acc Id: XM_040269549   ⟹   XP_040125483
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560255,515,472 - 55,526,599 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005337366   ⟸   XM_005337309
- Peptide Label: isoform X3
- UniProtKB: A0A287DBZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013219239   ⟸   XM_013363785
- Peptide Label: isoform X4
- UniProtKB: I3MS41 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040125482   ⟸   XM_040269548
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040125483   ⟸   XM_040269549
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000031044   ⟸   ENSSTOT00000041176
RefSeq Acc Id: ENSSTOP00000014936   ⟸   ENSSTOT00000028726


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000025783 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000028726.2 UniProtKB/TrEMBL
  ENSSTOT00000041176.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.490.10 UniProtKB/TrEMBL
  atp-gated p2x4 ion channel UniProtKB/TrEMBL
InterPro P2X5_purnocptor UniProtKB/TrEMBL
  P2X_extracellular_dom_sf UniProtKB/TrEMBL
  P2X_purnocptor UniProtKB/TrEMBL
NCBI Gene P2rx5 ENTREZGENE
PANTHER P2X PURINOCEPTOR UniProtKB/TrEMBL
  PTHR10125:SF12 UniProtKB/TrEMBL
Pfam P2X_receptor UniProtKB/TrEMBL
PIRSF P2X_purinoceptor UniProtKB/TrEMBL
PRINTS P2X5RECEPTOR UniProtKB/TrEMBL
  P2XRECEPTOR UniProtKB/TrEMBL
UniProt A0A287DBZ3 ENTREZGENE, UniProtKB/TrEMBL
  I3MS41 ENTREZGENE, UniProtKB/TrEMBL